Host Protein General Information

  Protein Name
C-C chemokine receptor type 5
  Gene Name
CCR5
  Host Species
Homo sapiens
  Uniprot Entry Name
CCR5_HUMAN
  Protein Families
G-protein coupled receptor 1 family
  Subcellular Location
Cell membrane
  External Link
NCBI Gene ID
1234
Uniprot ID
P51681
Ensembl ID
ENSG00000153944
HGNC ID
1606
  Related KEGG Pathway
Viral life cycle - HIV-1 hsa03250            Pathway Map 
Virion - Human immunodeficiency virus hsa03260            Pathway Map 
Chemokine signaling pathway hsa04062            Pathway Map 
Toxoplasmosis hsa05145            Pathway Map 
Human cytomegalovirus infection hsa05163            Pathway Map 
Kaposi sarcoma-associated herpesvirus infection hsa05167            Pathway Map 
Human immunodeficiency virus 1 infection hsa05170            Pathway Map 
Cytokine-cytokine receptor interaction hsa04060            Pathway Map 
Viral protein interaction with cytokine and cytokine receptor hsa04061            Pathway Map 
Endocytosis hsa04144            Pathway Map 
Viral carcinogenesis hsa05203            Pathway Map 
  3D Structure
PDB ID: 2L87 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Human immunodeficiency virus type 1 (strain JR-CSF) 5'UTR - 3'UTR RNA Info Genome-wide CRISPR screen strategy GXRCas9 Cells (Human acute lymphoid leukemia T lymphoid cell line) . Lymph . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
abametapir . 15664  D5IS6V  DrugCentral
ANCRIVIROC . 9574343  D0G6JE  DGIdb
APLAVIROC . 3001322  D0G6SZ  DGIdb
APLAVIROC HYDROCHLORIDE . 3001322  D0G6SZ  DGIdb
AZD5672 . 11614352  D07GIB  DGIdb
CENICRIVIROC . 11285792  D0YQ7U  DGIdb
disulfiram . 3117  D0X5SD  DrugCentral
INCB-9471 . 49871007  D0Y7NA  DGIdb
MARAVIROC . 3002977  D0NR6S  DGIdb
maraviroc . 3002977  D0NR6S  DrugCentral
PF-04634817 . 46198579  D0D9HA  DGIdb
PF-232798 . 53316710  D0F7PZ  DGIdb
terfenadine . 5405  D08SOF  DrugCentral
VICRIVIROC . 3009355  D09JLI  DGIdb

Protein Sequence Information

MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
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