Host Protein General Information

  Protein Name
Histone deacetylase 2
  Gene Name
HDAC2
  Host Species
Homo sapiens
  Uniprot Entry Name
HDAC2_HUMAN
  Protein Families
Histone deacetylase family, HD type 1 subfamily
  EC Number
3.5.1.-; 3.5.1.98
  Subcellular Location
Nucleus
  External Link
NCBI Gene ID
3066
Uniprot ID
Q92769
Ensembl ID
ENSG00000196591
HGNC ID
4853
  Related KEGG Pathway
Neutrophil extracellular trap formation hsa04613            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
Epstein-Barr virus infection hsa05169            Pathway Map 
Longevity regulating pathway - multiple species hsa04213            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Transcriptional misregulation in cancer hsa05202            Pathway Map 
Viral carcinogenesis hsa05203            Pathway Map 
MicroRNAs in cancer hsa05206            Pathway Map 
Chronic myeloid leukemia hsa05220            Pathway Map 
Cell cycle hsa04110            Pathway Map 
Thyroid hormone signaling pathway hsa04919            Pathway Map 
Huntington disease hsa05016            Pathway Map 
Notch signaling pathway hsa04330            Pathway Map 
TGF-beta signaling pathway hsa04350            Pathway Map 
Amphetamine addiction hsa05031            Pathway Map 
Alcoholism hsa05034            Pathway Map 
  3D Structure
PDB ID: 3MAX 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 4 (strain DENV-4/SG/06K2270DK1/2005) 3'UTR RNA Info RNA chromatography and quantitative mass spectrometry HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 24 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
7-ETHYL-10-HYDROXYCAMPTOTHECIN . 104842  D0B6YB  DGIdb
ABEXINOSTAT . 11749858  D0V0SL  DGIdb
AN-9 . 60748  D0MP2U  DGIdb
APICIDIN . 6918328  D0W1PV  DGIdb
AR-42 . 6918848  D07KDI  DGIdb
atorvastatin . 60823  D01QIN  DrugCentral
BELINOSTAT . 6918638  D0XT6W  DGIdb
belinostat . 6918638  D0XT6W  DrugCentral
bendamustine . . . DrugCentral
BUTANOIC ACID . 264  D0T4JQ  DGIdb
CHIDAMIDE . . . DGIdb
chidamide . . . DrugCentral
CITARINOSTAT . 53340426  D01WKZ  DGIdb
CUDC-101 . 24756910  D0Z4RC  DGIdb
DACINOSTAT . 6445533  D0B3FV  DGIdb
DAUNORUBICIN . 30323  D01XWG  DGIdb
DEPAKOTE . 23663956  D03LGY  DGIdb
ENTINOSTAT . 4261  D0M8FD  DGIdb
FIMEPINOSTAT . 54575456  D0E6UZ  DGIdb
GIVINOSTAT . 9804992  D0GH3Q  DGIdb
HINOKITIOL . 3611  D0H4YW  DGIdb
LARGAZOLE . 24757913  D0Z8PX  DGIdb
lovastatin . 53232  D06WTZ  DrugCentral
MOCETINOSTAT . 9865515  D00FHR  DGIdb
PANOBINOSTAT . 6918837  D0E3SH  DGIdb
panobinostat . 6918837  D0E3SH  DrugCentral
PAZOPANIB . . . DGIdb
PHENYLBUTANOIC ACID . . . DGIdb
phenylbutanoic acid . . . DrugCentral
PHENYLBUTYRYLHYDROXAMIC ACID . 279980  D02NWS  DGIdb
PRACINOSTAT . 49855250  D0L2UQ  DGIdb
PSAMMAPLIN A . 6400741  D0N0TS  DGIdb
RESMINOSTAT . 11609955  D01UXJ  DGIdb
ROMIDEPSIN . 5352062  D0L7LC  DGIdb
romidepsin . 5352062  D0L7LC  DrugCentral
SCRIPTAID . 5186  D0J8OC  DGIdb
SUBEROHYDROXAMIC ACID . 5173  D07YZZ  DGIdb
TACEDINALINE . 2746  D0W9NH  DGIdb
TRICHOSTATIN . 444732  D0NF6F  DGIdb
VALPROIC ACID . . . DGIdb
valproic acid . . . DrugCentral
VORINOSTAT . 5311  D0E7PQ  DGIdb
vorinostat . 5311  D0E7PQ  DrugCentral

Protein Sequence Information

MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP
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