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| Strain Information | Strain Name |
West Nile Virus (strain EG101)
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| Strain Family |
Flaviviridae
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| RNA Binding Site |
3'UTR
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| Virus Information | Virus Name |
West Nile Virus (WNV)
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| Taxonomy ID | 11082 | ||||||||
Full list of proteins interacting with the 3'UTR of this Strain
| Protein Name | Uniprot ID | Host Species | Pro Info | Detection Method | Infection Cell | Cell ID | Cell Originated Tissue | Infection Time | Interaction Score | Fold Change |
|---|---|---|---|---|---|---|---|---|---|---|
| Elongation factor 1-alpha 1 | P62629 | Cricetulus griseus | Pro Info | Coimmunoprecipitation (Co-IP) and western blotting (WB) | BHK-21 Cells (Small hamster kidney fibroblast); BHK-WI2 Cells (Small hamster kidney fibroblast) | . | Kidney | 24 h | . | . |
| Nucleolysin TIA-1 | P52912 | Mus musculus | Pro Info | Co-immunoprecipitation assays (Co-IP) | BHK-21 Cells (Small hamster kidney fibroblast) | . | Kidney | 1 h | . | . |
| Nucleolysin TIA-1 isoform p40 | P31483 | Homo sapiens | Pro Info | Competition gel mobility shift assays and UV cross-linking (UVX) | BHK Cells (Small hamster kidney fibroblast) | . | Kidney | . | . | . |
| Nucleolysin TIAR | Q01085 | Homo sapiens | Pro Info | Competition gel mobility shift assays and UV cross-linking (UVX) | BHK Cells (Small hamster kidney fibroblast) | . | Kidney | . | . | . |
| Nucleolysin TIAR | P70318 | Mus musculus | Pro Info | Co-immunoprecipitation assays (Co-IP) | BHK-21 Cells (Small hamster kidney fibroblast) | . | Kidney | 1 h | . | . |
Functional Go Enrichment analysis of those proteins interacting with the 3'UTR of this Strain
| GO Term | GO Category | GO ID | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|---|
| mRNA 3'-UTR Binding | Molecular Function |
GO:0003730
|
0.000831684 | 437.4945055 | 4224.887763 |
| RNA Binding | Molecular Function |
GO:0003723
|
0.002277889 | 55767 | 443699.4499 |
| mRNA Binding | Molecular Function |
GO:0003729
|
0.002551385 | 140.8357143 | 1047.459405 |
| poly Binding | Molecular Function |
GO:0008143
|
0.012071706 | 416.1041667 | 2324.863325 |
| Poly-Purine Tract Binding | Molecular Function |
GO:0070717
|
0.012071706 | 332.7833333 | 1787.845974 |
| tRNA Binding | Molecular Function |
GO:0000049
|
0.016533405 | 199.47 | 972.5284118 |
| GTP Binding | Molecular Function |
GO:0005525
|
0.051944711 | 49.4925 | 173.7975592 |
| Guanyl Ribonucleotide Binding | Molecular Function |
GO:0032561
|
0.051944711 | 43.93777778 | 149.1959056 |
| GTPase Activity | Molecular Function |
GO:0003924
|
0.051944711 | 37.37310606 | 121.0283454 |
| Ribonucleoside Triphosphate Phosphatase Activity | Molecular Function |
GO:0017111
|
0.051944711 | 36.66914498 | 118.0724335 |
| Kinase Binding | Molecular Function |
GO:0019900
|
0.074711636 | 21.2832244 | 57.39430108 |
| Purine Ribonucleoside Triphosphate Binding | Molecular Function |
GO:0035639
|
0.074711636 | 20.54947368 | 54.72955385 |
| Protein Kinase Binding | Molecular Function |
GO:0019901
|
0.074711636 | 19.10490196 | 49.56039732 |
| Cytoplasmic Stress Granule | Cellular Component |
GO:0010494
|
0.000810248 | 538.4594595 | 5418.307392 |
| Nuclear Stress Granule | Cellular Component |
GO:0097165
|
0.007123399 | 2499.125 | 17982.859 |
| Cytoplasmic Side Of Lysosomal Membrane | Cellular Component |
GO:0098574
|
0.011393513 | 908.4545455 | 5741.921288 |
| Cortical Actin Cytoskeleton | Cellular Component |
GO:0030864
|
0.031282261 | 232.0232558 | 1165.417706 |
| Cortical Cytoskeleton | Cellular Component |
GO:0030863
|
0.035739719 | 160.766129 | 749.9503377 |
| Nucleus | Cellular Component |
GO:0005634
|
0.035739719 | 46539 | 208688.8874 |
| Cytoplasmic Vesicle Lumen | Cellular Component |
GO:0060205
|
0.038712569 | 87.20614035 | 354.550257 |
| Intracellular Membrane-Bounded Organelle | Cellular Component |
GO:0043231
|
0.038712569 | 44475 | 180395.7789 |
| Ficolin-1-Rich Granule Lumen | Cellular Component |
GO:1904813
|
0.038712569 | 81.45491803 | 325.7223629 |
| Ficolin-1-Rich Granule | Cellular Component |
GO:0101002
|
0.05196127 | 54.13661202 | 194.8436501 |
| Lytic Vacuole | Cellular Component |
GO:0000323
|
0.057137941 | 44.53828829 | 151.8234808 |
| Secretory Granule Lumen | Cellular Component |
GO:0034774
|
0.070525876 | 31.24126984 | 95.75231449 |
| Actin Cytoskeleton | Cellular Component |
GO:0015629
|
0.070525876 | 30.1702454 | 91.45401568 |
| Lysosomal Membrane | Cellular Component |
GO:0005765
|
0.071192264 | 27.66478873 | 81.54895757 |
| Lysosome | Cellular Component |
GO:0005764
|
0.09319076 | 19.41733068 | 50.66943668 |
| Nucleolus | Cellular Component |
GO:0005730
|
0.125736862 | 12.48506494 | 27.416445 |
| Nuclear Lumen | Cellular Component |
GO:0031981
|
0.125736862 | 12.33504493 | 26.94947775 |
| Intracellular Organelle Lumen | Cellular Component |
GO:0070013
|
0.129821127 | 11.19415205 | 23.45919201 |
| Intracellular Non-Membrane-Bounded Organelle | Cellular Component |
GO:0043232
|
0.168760683 | 7.873953099 | 14.00991724 |
| Regulation Of Chaperone-Mediated Autophagy | Biological Process |
GO:1904714
|
0.011694499 | 1665.916667 | 11427.00155 |
| Protein Localization To Cytoplasmic Stress Granule | Biological Process |
GO:1903608
|
0.011694499 | 1665.916667 | 11427.00155 |
| Positive Regulation Of miRNA-mediated Gene Silencing | Biological Process |
GO:2000637
|
0.011694499 | 1249.3125 | 8255.546445 |
| Positive Regulation Of Hippo Signaling | Biological Process |
GO:0035332
|
0.011694499 | 1249.3125 | 8255.546445 |
| Positive Regulation Of Post-Transcriptional Gene Silencing By RNA | Biological Process |
GO:1900370
|
0.011694499 | 1110.444444 | 7220.954199 |
| Regulation Of miRNA-mediated Gene Silencing | Biological Process |
GO:0060964
|
0.014195537 | 713.6785714 | 4351.685757 |
| Positive Regulation By Host Of Viral Process | Biological Process |
GO:0044794
|
0.014195537 | 624.40625 | 3729.253306 |
| Modulation By Host Of Viral Genome Replication | Biological Process |
GO:0044827
|
0.014340222 | 499.425 | 2877.37169 |
| Stress Granule Assembly | Biological Process |
GO:0034063
|
0.014340222 | 434.2173913 | 2443.769793 |
| Regulation Of Hippo Signaling | Biological Process |
GO:0035330
|
0.014340222 | 416.1041667 | 2324.863325 |
| Cellular Response To Epidermal Growth Factor Stimulus | Biological Process |
GO:0071364
|
0.014340222 | 384.0576923 | 2116.293582 |
| Response To Epidermal Growth Factor | Biological Process |
GO:0070849
|
0.014603598 | 344.2758621 | 1860.860041 |
| Regulation Of mRNA Processing | Biological Process |
GO:0050684
|
0.01572303 | 293.5735294 | 1541.625367 |
| Translational Elongation | Biological Process |
GO:0006414
|
0.017513828 | 243.3658537 | 1233.68694 |
| Regulation Of Alternative mRNA Splicing, Via Spliceosome | Biological Process |
GO:0000381
|
0.020616068 | 191.7788462 | 927.6718551 |
| Negative Regulation Of Amide Metabolic Process | Biological Process |
GO:0034249
|
0.031131645 | 108.1793478 | 462.6710098 |
| Regulation Of mRNA Splicing, Via Spliceosome | Biological Process |
GO:0048024
|
0.031131645 | 107.0107527 | 456.5339024 |
| Negative Regulation Of Macromolecule Biosynthetic Process | Biological Process |
GO:0010558
|
0.031131645 | 102.5773196 | 433.3656574 |
| Regulation Of RNA Splicing | Biological Process |
GO:0043484
|
0.031131645 | 98.4950495 | 412.1983924 |
| Negative Regulation Of Translation | Biological Process |
GO:0017148
|
0.031131645 | 93.8254717 | 388.1897375 |
Functional KEGG Enrichment analysis of those proteins interacting with the 3'UTR of this Strain
| Pathways | Category | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|
| Legionellosis | KEGG Pathway | 0.017259077 | 178.0446429 | 848.3179948 |
| Leishmaniasis | KEGG Pathway | 0.017259077 | 131.0592105 | 585.1639325 |
| RNA transport | KEGG Pathway | 0.027642526 | 53.54594595 | 192.1442664 |
Virus RNA Sequence Information
|
>M12294.2 West Nile virus RNA, complete genome
AGTAGTTCGCCTGTGTGAGCTGACAAACTTAGTAGTGTTTGTGAGGATTAACAACAATTAACACAGTGCG
AGCTGTTTCTTGGCACGAAGATCTCGATGTCTAAGAAACCAGGAGGGCCCGGTAAAAACCGGGCTGTCAA
TATGCTAAAACGCGGTATGCCCCGCGGATTGTCCTTGATAGGACTAAAGAGGGCTATGCTGAGTCTGATT
GACGGGAAGGGCCCAATACGTTTCGTGTTGGCTCTTTTGGCGTTTTTCAGATTCACTGCAATCGCTCCGA
CTCGTGCGGTGCTGGACAGATGGAGAGGCGTCAACAAACAAACAGCAATGAAGCATCTCTTGAGTTTCAA
GAAAGAACTAGGAACTCTGACCAGTGCCATCAACCGCCGGAGCACAAAACAAAAGAAAAGAGGAGGCACA
GCGGGCTTTACTATCTTGCTTGGGCTGATCGCCTGTGCTGGAGCTGTGACCCTCTCGAACTTCCAGGGCA
AAGTGATGATGACAGTCAATGCAACCGATGTCACTGACGTGATTACCATTCCAACAGCTGCTGGGAAAAA
CCTGTGCATCGTAAGGGCTATGGACGTAGGATACCTTTGTGAGGATACTATCACTTATGAATGTCCGGTC
CTAGCTGCTGGAAATGACCCTGAAGACATTGACTGCTGGTGCACGAAATCATCTGTTTACGTGCGCTATG
GAAGATGCACAAAAACTCGGCATTCCCGTCGAAGCAGAAGGTCTCTGACAGTCCAGACACATGGAGAAAG
TACACTGGCCAACAAGAAAGGAGCTTGGTTGGACAGCACAAAAGCCACGAGATATCTGGTGAAGACAGAA
TCATGGATACTGAGAAACCCGGGCTACGCCCTCGTTGCAGCTGTCATTGGATGGATGCTAGGAAGCAACA
CAATGCAACGCGTCGTGTTTGCCATTCTATTGCTCCTGGTGGCACCAGCATACAGCTTCAACTGTTTAGG
AATGAGTAACAGAGACTTCCTGGAGGGAGTGTCTGGAGCTACATGGGTTGATCTGGTACTGGAAGGCGAT
AGTTGTGTGACCATAATGTCAAAAGACAAGCCAACCATTGATGTCAAAATGATGAACATGGAAGCAGCCA
ACCTCGCAGATGTGCGCAGTTACTGTTACCTAGCTTCGGTCAGTGACTTGTCAACAAGAGCTGCGTGTCC
AACCATGGGTGAAGCCCACAACGAGAAAAGAGCTGACCCCGCCTTCGTTTGCAAGCAAGGCGTTGTGGAC
AGAGGATGGGGAAATGGCTGCGGACTGTTTGGAAAGGGGAGCATTGACACATGTGCGAAGTTTGCCTGTA
CAACCAAAGCAACTGGATGGATCATCCAGAAGGAAAACATCAAGTATGAGGTTGCCATATTTGTGCATGG
CCCGACGACCGTTGAATCTCATGGCAAGATAGGGGCCACCCAGGCTGGAAGATTCAGTATAACTCCATCG
GCGCCATCTTACACGCTAAAGTTGGGTGAGTATGGTGAGGTTACGGTTGATTGTGAGCCACGGTCAGGAA
TAGACACCAGCGCCTATTACGTTATGTCAGTTGGTGAGAAGTCCTTCCTGGTTCACCGAGAATGGTTTAT
GGATCTGAACCTGCCATGGAGCAGTGCTGGAAGCACCACGTGGAGGAACCGGGAAACACTGATGGAGTTT
GAAGAACCTCATGCCACCAAACAATCTGTTGTGGCTCTAGGGTCGCAGGAAGGTGCGTTGCACCAAGCTC
TGGCCGGAGCGATTCCTGTTGAGTTCTCAAGCAACACTGTGAAGTTGACATCAGGACATCTGAAGTGTCG
GGTGAAGATGGAGAAGTTGCAGCTGAAGGGAACAACATATGGAGTATGTTCAAAAGCGTTCAAATTCGCT
AGGACTCCCGCTGACACTGGCCACGGAACGGTGGTGTTGGAACTGCAATATACCGGAACAGACGGTCCCT
GCAAAGTGCCCATTTCTTCCGTAGCTTCCCTGAATGACCTCACACCTGTTGGAAGACTGGTGACCGTGAA
TCCATTTGTGTCTGTGGCCACAGCCAACTCGAAGGTTTTGATTGAACTCGAACCCCCGTTTGGTGACTCT
TACATCGTGGTGGGAAGAGGAGAACAGCAGATAAACCATCACTGGCACAAATCTGGGAGCAGCATTGGAA
AGGCCTTTACCACCACACTCAGAGGAGCTCAACGACTCGCAGCTCTTGGAGATACTGCTTGGGATTTTGG
ATCAGTTGGAGGGGTTTTCACCTCAGTGGGGAAAGCCATACACCAAGTCTTTGGAGGAGCTTTTAGATCA
CTCTTTGGAGGGATGTCCTGGATCACACAGGGACTTCTGGGAGCTCTTCTGTTGTGGATGGGAATCAATG
CCCGTGACAGGTCAATTGCTATGACGTTTCTTGCGGTTGGAGGAGTTTTGCTCTTCCTTTCGGTCAACGT
CCATGCTGACACAGGCTGTGCCATTGATATTGGCAGGCAAGAGCTCCGGTGCGGAAGTGGAGTGTTTATC
CACAACGATGTGGAAGCCTGGATGGATCGTTACAAGTTCTACCCGGAGACGCCACAGGGCCTAGCAAAAA
TTATCCAGAAAGCACATGCAGAAGGAGTCTGCGGCTTGCGTTCCGTTTCCAGACTCGAGCACCAAATGTG
GGAAGCCATTAAGGATGAGCTGAACACCCTGTTGAAAGAGAATGGAGTCGACTTGAGTGTCGTGGTGGAA
AAACAGAATGGGATGTACAAAGCAGCACCAAAACGTTTGGCTGCCACCACCGAAAAACTGGAGATGGGTT
GGAAGGCTTGGGGCAAGAGTATCATCTTTGCGCCAGAACTAGCTAACAACACCTTTGTCATCGACGGTCC
TGAGACTGAGGAATGCCCAACGGCCAACCGAGCATGGAACAGTATGGAGGTAGAGGACTTTGGATTTGGA
CTGACAAGCACTCGCATGTTCCTGAGGATTCGGGAAACGAACACAACGGAATGCGACTCGAAGATCATAG
GAACCGCCGTCAAGAACAACATGGCTGTGCATAGTGATCTATCATACTGGATAGAGAGCGGACTCAACGA
CACCTGGAAGCTTGAGAGGGCGGTTCTAGGAGAAGTCAAATCATGCACCTGGCCAGAAACCCACACTCTG
TGGGGTGATGGAGTTCTGGAAAGTGATCTCATCATACCCATCACCTTGGCAGGACCCAGAAGCAACCACA
ACAGGAGACCAGGGTACAAAACTCAGAACCAAGGCCCATGGGATGAGGGGCGCGTCGAGATTGACTTTGA
CTATTGCCCAGGAACAACAGTAACTATAAGTGACAGTTGCGAACACCGTGGACCTGCGGCACGCACAACC
ACTGAGAGTGGGAAGCTCATCACAGACTGGTGCTGCAGAAGTTGCACCCTCCCTCCACTGCGCTTCCAGA
CTGAGAATGGCTGTTGGTATGGAATGGAAATTCGACCTACGCGGCACGACGAAAAGACCCTCGTGCAATC
GAGAGTGAATGCATACAACGCCGACATGATTGATCCTTTTCAGTTGGGCCTTATGGTCGTGTTCTTGGCC
ACCCAGGAGGTCCTTCGCAAGAGGTGGACGGCCAAGATCAGCATTCCAGCTATCATGCTTGCACTCCTAG
TCCTAGTGTTTGGGGGTATTACGTACACTGATGTCCTGCGATATGTCATTCTCGTCGGCGCCGCGTTTGC
TGAAGCAAACTCAGGAGGAGACGTCGTGCACTTGGCACTTATGGCTACATTCAAGATTCAACCAGTCTTT
CTGGTGGCTTCCTTTTTGAAGGCAAGGTGGACCAACCAAGAGAGTATTTTGCTCATGCTTGCAGCTGCTT
TCTTCCAAATGGCTTACTATGACGCCAAGAATGTTCTGTCATGGGAAGTGCCTGACGTTTTGAACTCTCT
CTCCGTTGCGTGGATGATTCTCAGAGCTATAAGCTTCACCAACACTTCAAATGTGGTGGTGCCGCTGCTG
GCCCTTTTGACACCTGGATTGAAATGCTTAAACCTTGATGTGTACAGAATTTTGCTACTCATGGTTGGAG
TTGGAAGCCTCATCAAAGAAAAAAGGAGCTCTGCAGCAAAAAAGAAAGGAGCTTGCCTCATCTGCCTAGC
GCTGGCGTCTACAGGAGTGTTCAATCCAATGATACTTGCAGCTGGGCTAATGGCTTGCGACCCCAACCGC
AAGCGGGGCTGGCCTGCTACAGAAGTGATGACTGCAGTTGGACTCATGTTTGCCATCGTTGGGGGTCTGG
CAGAACTTGACATAGATTCTATGGCTATCCCCATGACCATCGCCGGACTTATGTTCGCGGCATTTGTCAT
CTCTGGAAAGTCAACAGACATGTGGATTGAGAGGACGGCTGACATTACTTGGGAGAGTGATGCTGAAATC
ACAGGCTCTAGCGAAAGAGTAGATGTGAGGCTGGATGATGATGGAAATTTTCAACTGATGAATGACCCCG
GGGCACCATGGAAAATTTGGATGCTTAGGATGGCCTGCCTGGCGATAAGTGCCTACACACCTTGGGCAAT
TCTCCCCTCGGTCATCGGATTCTGGATAACCCTTCAGTACACAAAGAGAGGAGGTGTTCTTTGGGACACA
CCATCACCCAAGGAGTACAAGAAGGGTGATACCACCACTGGCGTTTACAGAATCATGACTCGAGGTCTGC
TTGGCAGTTACCAAGCTGGAGCCGGAGTGATGGTAGAGGGGGTGTTCCACACACTATGGCACACCACTAA
GGGAGCTGCTCTCATGAGTGGTGAGGGACGTCTGGATCCCTACTGGGGGAGCGTGAAAGAGGACCGACTT
TGCTATGGGGGGCCATGGAAACTCCAACATAAATGGAATGGACATGATGAGGTCCAAATGATTGTCGTGG
AGCCAGGGAAAAATGTGAAAAACGTCCAGACCAAGCCCGGAGTGTTTAAGACACCAGAAGGAGAAATTGG
GGCAGTTACGCTAGACTATCCTACCGGAACGTCAGGTTCCCCCATTGTAGACAAAAATGGAGATGTGATT
GGATTGTATGGGAACGGCGTCATCATGCCTAATGGTTCATACATAAGCGCCATTGTGCAAGGAGAGAGAA
TGGAAGAACCGGCACCAGCTGGCTTCGAACCTGAAATGTTGAGGAAGAAACAGATCACTGTCCTTGATCT
GCACCCCGGAGCAGGAAAGACACGCAAGATACTTCCCCAAATCATCAAGGAGGCCATCAACAAAAGATTG
AGGACGGCTGTGCTGGCACCCACCAGGGTCGTTGCTGCTGAGATGTCTGAGGCCCTGAGAGGACTTCCCA
TTCGGTACCAAACCTCAGCAGTGCACAGAGAGCACAGTGGAAATGAGATCGTTGATGTCATGTGCCATGC
CACCCTCACACACAGGCTGATGTCTCCACACAGAGTCCCCAACTACAACCTGTTCATAATGGATGAAGCC
CATTTCACGGATCCAGCGAGCATCGCAGCCAGAGGATACATAGCAACCAAGGTTGAATTGGGCGAAGCCG
CCGCGATTTTCATGACGGCAACGCCACCCGGGACTTCTGACCCCTTTCCAGAGTCTAATGCTCCTATCTC
GGACATGCAAACAGAGATCCCAGACAGAGCCTGGAACACTGGATATGAATGGATAACTGAGTATGTTGGA
AAGACCGTTTGGTTTGTTCCAAGTGTGAAAATGGGAAATGAGATTGCCCTCTGTCTGCAACGGGCGGGGA
AGAAGGTTATCCAGCTGAACAGAAAGTCCTATGAGACAGAGTACCCCAAGTGTAAGAACGATGATTGGGA
TTTTGTCATCACCACAGACATATCAGAAATGGGAGCCAACTTCAAGGCGAGCAGAGTGATCGACAGCCGC
AAAAGCGTGAAACCCACCATCATTGAGGAAGGTGATGGAAGAGTCATCCTGGGGGAACCCTCAGCCATCA
CGGCTGCCAGCGCTGCTCAGCGGAGAGGACGCATAGGAAGAAACCCATCACAAGTTGGTGATGAGTATTG
CTATGGAGGGCACACAAATGAGGATGATTCCAACTTTGCTCACTGGACAGAGGCTCGCATCATGCTAGAC
AACATCAACATGCCGAATGGTCTGGTGGCTCAACTATATCAGCCTGAGCGCGAGAAGGTGTACACCATGG
ACGGGGAATACAGGCTCAGAGGGGAAGAACGGAAGAACTTCCTTGAATTCCTGAGAACAGCTGATTTACC
AGTCTGGCTCGCTTACAAAGTGGCAGCAGCAGGAATATCATACCATGACCGGAAATGGTGCTTTGATGGA
CCTCGAACCAACACGATTCTTGAAGACAACAATGAAGTTGAAGTCATCACGAAGTTGGGTGAGAGAAAGA
TCCTAAGACCCAGGTGGGCAGATGCTAGAGTGTACTCAGACCATCAAGCTCTAAAGTCCTTCAAAGATTT
TGCATCGGGGAAACGATCACAAATCGGGCTCGTTGAGGTGCTCGGGAGAATGCCTGAACACTTCATGGTG
AAAACTTGGGAGGCATTGGACACGATGTATGTGGTGGCGACCGCTGAAAAAGGAGGCCGAGCTCACAGGA
TGGCTCTTGAGGAGCTACCGGACGCCCTTCAGACAATAGTTTTGATTGCACTATTGAGTGTGATGTCCTT
AGGTGTGTTTTTTCTACTCATGCAAAGGAAGGGCATTGGTAAGATTGGCTTGGGAGGAGTAATCTTAGGA
GCTGCCACATTCTTCTGCTGGATGGCTGAAGTCCCAGGAACGAAAATAGCAGGCATGCTCCTGCTTTCCC
TGCTGCTCATGATTGTTTTGATTCCGGAGCCGGAAAAGCAGCGCTCACAGACTGATAACCAGCTCGCCGT
GTTCTTGATCTGTGTGCTCACACTGGTCGGCGCCGTGGCTGCCAATGAAATGGGCTGGCTGGACAAGACC
AAGAATGACATTGGCAGCCTGTTGGGGCACAGGCCAGAAGCTAGAGAGACGACCCTGGGAGTTGAGAGCT
TCTTACTTGATCTGCGGCCGGCCACGGCATGGTCGCTCTATGCCGTAACGACAGCCGTTCTCACCCCTTT
GCTGAAGCATCTAATCACGTCAGACTACATCAACACTTCGTTGACCTCAATAAACGTCCAAGCCAGCGCG
TTGTTCACTTTGGCCAGAGGCTTCCCTTTTGTGGACGTTGGTGTGTCAGCTCTCTTGCTGGCGGTCGGGT
GCTGGGGTCAGGTGACTCTGACTGTGACTGTGACTGCAGCTGCTCTGCTCTTTTGCCACTATGCTTACAT
GGTGCCAGGCTGGCAAGCGGAAGCCATGCGATCTGCCCAGCGGCGGACAGCTGCTGGCATCATGAAAAAT
GTAGTGGTGGATGGGATCGTGGCCACTGATGTACCTGAACTTGAACGAACAACTCCAGTCATGCAGAAAA
AAGTTGGACAGATCATATTGATCTTGGTATCAATGGCCGCGGTGGTCGTCAATCCATCAGTGAGAACCGT
CAGAGAGGCCGGAATTCTGACTACAGCAGCAGCAGTCACCCTATGGGAGAATGGTGCTAGTTCAGTGTGG
AATGCAACGACAGCTATTGGCCTTTGTCACATCATGCGAGGAGGATGGCTCTCGTGTCTCTCCATCATGT
GGACTCTCATCAAAAACATGGAGAAACCAGGCCTCAAGAGGGGTGGAGCCAAAGGACGCACGCTAGGGGA
AGTTTGGAAGGAGAGACTCAACCACATGACGAAGGAAGAATTTACCAGATACAGAAAAGAAGCCATCACT
GAAGTTGACCGCTCCGCAGCAAAACATGCTAGGAGAGAGGGAAACATCACTGGAGGCCACCCAGTCTCAC
GGGGAACCGCGAAATTACGGTGGTTAGTGGAAAGGCGTTTCCTCGAGCCAGTGGGAAAGGTTGTGGATCT
CGGGTGTGGTAGAGGCGGCTGGTGCTATTACATGGCTACCCAGAAGAGGGTACAGGAAGTGAAAGGGTAC
ACGAAAGGAGGACCTGGCCATGAAGAACCACAACTGGTGCAGAGCTATGGTTGGAATATTGTTACCATGA
AGAGTGGAGTCGACGTCTTCTACAGACCATCAGAAGCGAGCGACACACTGCTCTGTGACATTGGAGAGTC
ATCGTCAAGTGCCGAGGTAGAAGAACACCGCACCGTCCGTGTCCTGGAGATGGTGGAAGATTGGTTGCAC
AGAGGACCGAAGGAATTCTGCATCAAAGTGCTATGCCCTTACATGCCCAAAGTGATTGAGAAGATGGAAA
CACTCCAAAGGCGATATGGAGGTGGCCTTATAAGAAACCCCCTTTCACGCAACTCTACCCATGAGATGTA
CTGGGTGAGCCACGCTTCAGGCAATATCGTCCACTCCGTCAACATGACAAGCCAGGTGCTTCTGGGGAGG
ATGGAAAAGAAAACATGGAAGGGACCCCAGTTTGAGGAAGATGTCAACTTGGGAAGTGGAACGCGGGCAG
TAGGGAAGCCTCTCCTCAATTCTGATACTAGCAAGATCAAGAACCGAATTGAGAGGCTGAAGAAAGAATA
CAGCTCCACATGGCACCAGGATGCGAACCACCCCTACAGGACCTGGAACTACCACGGAAGCTATGAAGTG
AAACCAACCGGCTCAGCCAGCTCCCTTGTGAATGGGGTAGTCAGATTACTCTCAAAACCATGGGACACTA
TCACCAATGTGACCACGATGGCCATGACAGACACCACTCCTTTCGGTCAACAACGAGTGTTCAAGGAAAA
GGTGGACACAAAGGCTCCAGAGCCTCCAGAAGGAGTCAAATACGTCCTCAATGAGACCACGAACTGGCTG
TGGGCTTTTTTAGCCCGCGATAAGAAACCCAGGATGTGTTCCCGGGAGGAATTTATTGGAAAAGTCAACA
GTAATGCCGCCCTAGGAGCGATGTTTGAAGAACAGAACCAATGGAAGAACGCCCGGGAAGCTGTAGAGGA
TCCAAAGTTTTGGGAGATGGTGGATGAGGAGCGTGAAGCGCATCTCCGTGGAGAATGCAACACCTGCATC
TACAACATGATGGGAAAGAGAGAGAAGAAGCCTGGAGAGTTCGGCAAAGCTAAAGGCAGCAGAGCCATCT
GGTTCATGTGGCTGGGGGCCCGCTTCCTGGAGTTTGAAGCTCTCGGATTCCTCAATGAAGACCACTGGCT
GGGTAGGAAGAACTCAGGAGGAGGAGTTGAAGGCTTAGGACTGCAGAAGCTCGGGTACATCTTGAAGGAA
GTTGGAACAAAGCCTGGAGGAAAGGTTTACGCTGATGATACCGCAGGCTGGGACACACGCATCACCAAAG
CTGACCTCGAGAATGAAGCGAAGGTTCTTGAACTGCTGGATGGAGAACATCGACGTTTAGCGCGGTCCAT
CATCGAGCTCACATACCGACACAAAGTCGTGAAAGTGATGAGGCCAGCGGCCGACGGGAAAACTGTGATG
GACGTCATCTCTAGAGAGGATCAGAGAGGAAGCGGTCAGGTAGTGACTTACGCCCTGAACACCTTCACCA
ATCTAGCAGTTCAGCTGGTCAGAATGATGGAGGGGGAGGGGGTCATTGGACCCGATGATGTTGAAAAACT
GGGAAAAGGAAAAGGCCCTAAGGTCAGAACCTGGCTGTTTGAGAATGGCGAGGAGCGTCTCAGTCGCATG
GCCGTCAGCGGTGATGACTGCGTGGTGAAACCTTTGGACGACCGCTTCGCCACATCACTACACTTCCTAA
ATGCTATGTCAAAGGTCCGCAAAGACATCCAGGAATGGAAACCCTCGACGGGGTGGTATGACTGGCAGCA
GGTTCCATTCTGTTCAAACCATTTCACGGAACTGATCATGAAGGACGGCAGGACGCTGGTGGTCCCGTGT
CGTGGACAAGACGAGTTGATTGGACGTGCCAGGATCTCTCCAGGGGCTGGATGGAATGTGCGCGACACCG
CCTGCCTGGCGAAGTCATACGCGCAGATGTGGCTGCTGCTTTATTTCCACCGTAGAGACCTGAGATTGAT
GGCCAATGCCATCTGTTCCGCTGTGCCTGCCAACTGGGTTCCCACAGGGCGTACCACTTGGTCGATCCAC
GCAAAAGGAGAATGGATGACGACGGAAGACATGCTCGCAGTCTGGAACAGAGTGTGGATTGAGGAGAATG
AGTGGATGGAAGACAAAACACCAGTTGAGAGGTGGAGTGATGTTCCATACTCTGGAAAGAGAGAGGACAT
TTGGTGTGGCAGTTTGATCGGCACACGAACCCGCGCCACTTGGGCTGAAAATATCCATGTGGCAATCAAT
CAGGTCCGTTCAGTGATTGGAGAAGAGAAGTATGTGGATTACATGAGCTCCTTGAGGAGGTATGAAGACA
CCATTGTAGTGGAGGACACTGTTTTGTAAAAGATAGTATTATAGTTAGTTTAGTGTAAATAGGATTTATT
GAGAATGGAAGTCAGGCCAGATTAATGCTGCCACCGGAAGTTGAGTAGACGGTGCTGCCTGCGGCTCAAC
CCCAGGAGGACTGGGTGACCAAAGCTGCGAGGTGATCCACGTAAGCCCTCAGAACCGTCTCGGAAGGAGG
ACCCCACGTGCTTTAGCCTCAAAGCCCAGTGTCAGACCACACTTTAATGTGCCACTCTGCGGAGAGTGCA
GTCTGCGATAGTGCCCCAGGTGGACTGGGTTAACAAAGGCAAAACATCGCCCCACGCGGCCATAACCCTG
GCTATGGTGTTAACCAGGGAGAAGGGACTAGAGGTTAGAGGAGACCCCGCGTAAAAAAGTGCACGGCCCA
ACTTGGCTGAAGCTGTAAGCCAAGGGAAGGACTAGAGGTTAGAGGAGACCCCGTGCCAAAAACACCAAAA
GAAACAGCATATTGACACCTGGGATAGACTAGGGGATCTTCTGCTCTGCACAACCAGCCACACGGCACAG
TGCGCCGACATAGGTGGCTGGTGGTGCTAGAACACAGGATCT
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