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| Strain Information | Strain Name |
Japanese encephalitis virus
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| Strain Family |
Flaviviridae
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| RNA Binding Site |
5'UTR - 3'UTR
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| Virus Information | Virus Name |
Japanese encephalitis virus (JEV)
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| Taxonomy ID | 11072 | ||||||||
Full list of proteins interacting with the 5'UTR - 3'UTR of this Strain
| Protein Name | Uniprot ID | Host Species | Pro Info | Detection Method | Infection Cell | Cell ID | Cell Originated Tissue | Infection Time | Interaction Score | Fold Change |
|---|---|---|---|---|---|---|---|---|---|---|
| Antiviral innate immune response receptor RIG-I | O95786 | Homo sapiens | Pro Info | . | B95a Cells (Marmoset lymphoblastoid cell line) | . | . | . | . | . |
| Antiviral innate immune response receptor RIG-I | O95786 | Homo sapiens | Pro Info | . | B95a Cells (Marmoset lymphoblastoid cell line) | . | . | . | . | . |
| Helicase with 2 CARD domains | Q9BYX4 | Homo sapiens | Pro Info | . | B95a Cells (Marmoset lymphoblastoid cell line) | . | . | . | . | . |
| Interferon-induced 56 kDa protein | Q64282 | Mus musculus | Pro Info | RNA immunoprecipitation assays (RIP) | Primary Mouse Embryo Fibroblasts (MEFs) | . | . | 24 h | . | . |
Functional Go Enrichment analysis of those proteins interacting with the 5'UTR - 3'UTR of this Strain
| GO Term | GO Category | GO ID | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|---|
| Single-Stranded RNA Binding | Molecular Function |
GO:0003727
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0.000175843 | 973.4634146 | 10913.3726 |
| Double-Stranded RNA Binding | Molecular Function |
GO:0003725
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0.000202374 | 632.8253968 | 6566.953388 |
| RNA Binding | Molecular Function |
GO:0003723
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0.001518593 | 55767 | 443699.4499 |
| Zinc Ion Binding | Molecular Function |
GO:0008270
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0.002794173 | 115.9764012 | 818.6628334 |
| Transition Metal Ion Binding | Molecular Function |
GO:0046914
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0.003616177 | 86.09251101 | 557.9477881 |
| Purine Ribonucleoside Triphosphate Binding | Molecular Function |
GO:0035639
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0.003616177 | 82.37552743 | 526.834975 |
| Ubiquitin-Protein Transferase Activator Activity | Molecular Function |
GO:0097027
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0.004453723 | 666.0666667 | 4018.416231 |
| Adenyl Nucleotide Binding | Molecular Function |
GO:0030554
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0.007544816 | 332.7833333 | 1787.845974 |
| GTP Binding | Molecular Function |
GO:0005525
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0.043115657 | 49.4925 | 173.7975592 |
| Guanyl Ribonucleotide Binding | Molecular Function |
GO:0032561
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0.043575786 | 43.93777778 | 149.1959056 |
| Ubiquitin Protein Ligase Binding | Molecular Function |
GO:0031625
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0.045639603 | 36.53148148 | 117.495948 |
| Ubiquitin-Like Protein Ligase Binding | Molecular Function |
GO:0044389
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0.045639603 | 34.21701389 | 107.8824533 |
| Adenyl Ribonucleotide Binding | Molecular Function |
GO:0032559
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0.045639603 | 31.96266234 | 98.66808196 |
| Bicellular Tight Junction | Cellular Component |
GO:0005923
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0.026360888 | 124.48125 | 549.514823 |
| Tight Junction | Cellular Component |
GO:0070160
|
0.026360888 | 108.1793478 | 462.6710098 |
| Apical Junction Complex | Cellular Component |
GO:0043296
|
0.026360888 | 94.72380952 | 392.7911748 |
| Actin Cytoskeleton | Cellular Component |
GO:0015629
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0.060318183 | 30.1702454 | 91.45401568 |
| Cytoskeleton | Cellular Component |
GO:0005856
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0.087189794 | 16.21989967 | 39.57117011 |
| Cellular Response To Exogenous dsRNA | Biological Process |
GO:0071360
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1.61E-08 | 59958 | 1320372.925 |
| Cellular Response To dsRNA | Biological Process |
GO:0071359
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1.61E-08 | 59949 | 1282709.491 |
| Response To Exogenous dsRNA | Biological Process |
GO:0043330
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1.03E-07 | 59895 | 1145927.374 |
| Antiviral Innate Immune Response | Biological Process |
GO:0140374
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1.79E-07 | 59862 | 1094934.565 |
| Defense Response To Symbiont | Biological Process |
GO:0140546
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5.00E-06 | 59556 | 877805.6963 |
| Defense Response To Virus | Biological Process |
GO:0051607
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8.72E-06 | 59433 | 832127.8833 |
| Positive Regulation Of Response To Cytokine Stimulus | Biological Process |
GO:0060760
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1.23E-05 | 3330.833333 | 44982.2155 |
| Regulation Of Response To Cytokine Stimulus | Biological Process |
GO:0060759
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1.42E-05 | 2854.714286 | 37762.80057 |
| Positive Regulation Of Interferon-Alpha Production | Biological Process |
GO:0032727
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2.20E-05 | 2102.947368 | 26641.75291 |
| Cytosolic Pattern Recognition Receptor Signaling Pathway | Biological Process |
GO:0002753
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2.39E-05 | 1902.47619 | 23747.75571 |
| Regulation Of Interferon-Alpha Production | Biological Process |
GO:0032647
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2.79E-05 | 1664.416667 | 20359.49794 |
| Positive Regulation Of Interferon-Beta Production | Biological Process |
GO:0032728
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4.96E-05 | 1174.294118 | 13587.33897 |
| Regulation Of Interferon-Beta Production | Biological Process |
GO:0032648
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8.89E-05 | 831.2083333 | 9065.264276 |
| Negative Regulation Of Viral Genome Replication | Biological Process |
GO:0045071
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9.29E-05 | 782.1960784 | 8438.749293 |
| Pattern Recognition Receptor Signaling Pathway | Biological Process |
GO:0002221
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9.68E-05 | 738.6296296 | 7886.7062 |
| Negative Regulation Of Viral Process | Biological Process |
GO:0048525
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0.000107871 | 675.8644068 | 7100.033934 |
| Positive Regulation Of Type I Interferon Production | Biological Process |
GO:0032481
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0.000111834 | 643.0645161 | 6693.282857 |
| Regulation Of Viral Genome Replication | Biological Process |
GO:0045069
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0.000115826 | 613.2923077 | 6326.837238 |
| Positive Regulation Of Interleukin-6 Production | Biological Process |
GO:0032755
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0.000134793 | 538.4594595 | 5418.307392 |
| Positive Regulation Of Response To Stimulus | Biological Process |
GO:0048584
|
0.000134793 | 531.2533333 | 5331.831421 |
Functional KEGG Enrichment analysis of those proteins interacting with the 5'UTR - 3'UTR of this Strain
| Pathways | Category | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|
| RIG-I-like receptor signaling pathway | KEGG Pathway | 0.035811795 | 144.4057971 | 658.4676625 |
| Measles | KEGG Pathway | 0.035811795 | 71.95289855 | 278.9842061 |
| Hepatitis C | KEGG Pathway | 0.035811795 | 63.59294872 | 238.8835479 |
| Hepatitis B | KEGG Pathway | 0.035811795 | 61.60248447 | 229.4906395 |
| Influenza A | KEGG Pathway | 0.035811795 | 57.97076023 | 212.5179211 |
| Coronavirus disease | KEGG Pathway | 0.040132614 | 42.78354978 | 144.1684391 |
| Herpes simplex virus 1 infection | KEGG Pathway | 0.072858688 | 19.61770624 | 51.38335336 |
Virus RNA Sequence Information
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>NC_001437.1 Japanese encephalitis virus, genome
AGAAGTTTATCTGTGTGAACTTCTTGGCTTAGTATCGTTGAGAAGAATCGAGAGATTAGTGCAGTTTAAA
CAGTTTTTTAGAACGGAAGATAACCATGACTAAAAAACCAGGAGGGCCCGGTAAAAACCGGGCTATCAAT
ATGCTGAAACGCGGCCTACCCCGCGTATTCCCACTAGTGGGAGTGAAGAGGGTAGTAATGAGCTTGTTGG
ACGGCAGAGGGCCAGTACGTTTCGTGCTGGCTCTTATCACGTTCTTCAAGTTTACAGCATTAGCCCCGAC
CAAGGCGCTTTTAGGCCGATGGAAAGCAGTGGAAAAGAGTGTGGCAATGAAACATCTTACTAGTTTCAAA
CGAGAACTTGGAACACTCATTGACGCCGTGAACAAGCGGGGCAGAAAACAAAACAAAAGAGGAGGAAATG
AAGGCTCAATCATGTGGCTCGCAAGCTTGGCAGTTGTCATAGCTTACGCAGGAGCAATGAAGTTGTCGAA
TTTCCAGGGGAAGCTTTTGATGACCATCAACAACACGGACATTGCAGACGTTATCGTGATTCCCACCTCA
AAAGGAGAGAACAGATGCTGGGTCCGGGCAATAGACGTCGGCTACATGTGTGAGGACACTATCACGTACG
AATGTCCTAAGCTCACCATGGGCAATGATCCAGAGGATGTGGATTGCTGGTGTGACAACCAAGAAGTCTA
CGTCCAATATGGACGGTGCACGCGGACCAGGCATTCCAAGCGAAGCAGGAGATCCGTGTCGGTCCAAACA
CATGGGGAGAGTTCACTAGTGAATAAAAAAGAGGCTTGGCTGGATTCAACGAAAGCCACACGGTATCTCA
TGAAAACTGAGAACTGGATCATAAGGAATCCTGGCTATGCTTTCCTGGCGGCGACACTTGGCTGGATGCT
TGGCAGTAACAACGGTCAACGCGTGGTATTTACCATCCTCCTGCTGTTGGTCGCTCCGGCTTACAGTTTT
AATTGTCTGGGAATGGGCAATCGTGACTTCATAGAAGGAGCCAGTGGAGCCACTTGGGTGGACTTGGTGC
TAGAAGGAGATAGCTGCTTGACAATCATGGCAAACGACAAACCAACATTGGACGTCCGCATGATTAACAT
CGAAGCTAGCCAACTTGCTGAGGTCAGAAGTTACTGCTATCATGCTTCAGTCACTGACATCTCGACGGTG
GCTCGGTGCCCCACGACTGGAGAAGCTCACAACGAGAAGCGAGCTGATAGTAGCTATGTGTGCAAACAAG
GCTTCACTGATCGTGGGTGGGGCAACGGATGTGGACTTTTCGGGAAGGGAAGCATTGACACATGTGCAAA
ATTCTCCTGCACCAGCAAAGCGATTGGAAGAACAATCCAGCCAGAAAACATCAAATACGAAGTTGGCATT
TTTGTGCATGGAACCACCACTTCGGAAAACCATGGGAATTATTCAGCGCAAGTTGGGGCGTCCCAGGCGG
CAAAGTTTACAATAACACCCAATGCTCCTTCGATAACCCTCAAACTTGGTGACTACGGAGAAGTCACGCT
GGACTGTGAGCCAAGGAGTGGACTGAACACTGAAGCGTTTTACGTCATGACCGTGGGGTCAAAGTCATTT
CTGGTCCATAGGGAATGGTTTCATGACCTCGCTCTCCCCTGGACGTCCCCTTCGAGCACAGCGTGGAGAA
ACAGAGAACTCCTCATGGAATTTGAAGAGGCGCACGCCACAAAACAGTCCGTTGTTGCTCTTGGGTCACA
GGAAGGAGGCCTCCATCAGGCGTTGGCAGGAGCCATCGTGGTGGAGTACTCAAGCTCAGTGAAGTTAACA
TCAGGCCACCTGAAATGTAGGCTGAAAATGGACAAACTGGCTCTGAAAGGCACAACCTATGGCATGTGTA
CAGAAAAATTCTCGTTCGCGAAAAATCCGGCGGACACTGGCCACGGAACAGTTGTCATTGAACTATCCTA
CTCTGGGAGTGATGGCCCCTGCAAAATTCCGATTGTCTCCGTTGCGAGCCTCAATGACATGACCCCCGTT
GGGCGGCTGGTGACAGTGAACCCTTTCGTCGCGACTTCCAGTGCCAACTCAAAGGTGCTGGTCGAGATGG
AACCCCCCTTCGGAGACTCCTACATCGTGGTTGGGAGGGGAGACAAGCAGATCAACCACCATTGGCACAA
AGCTGGAAGCACGCTAGGCAAGGCCTTTTCAACAACTTTGAAGGGAGCTCAAAGACTGGCAGCGTTGGGC
GACACAGCCTGGGACTTTGGCTCCATTGGAGGGGTCTTCAACTCCATAGGAAAAGCCGTTCACCAAGTGT
TTGGTGGTGCCTTCAGAACACTCTTTGGGGGAATGTCTTGGATCACACAAGGGCTAATGGGTGCCCTACT
ACTCTGGATGGGCGTCAACGCACGAGACCGATCAATTGCTTTGGCCTTCTTAGCCACAGGAGGTGTGCTC
GTGTTCTTAGCGACCAATGTGCATGCTGACACTGGATGTGCCATTGACATCACAAGAAAAGAGATGAGAT
GTGGAAGTGGCATCTTTGTGCACAACGACGTGGAAGCCTGGGTGGACAGGTATAAATACTTGCCAGAAAC
GCCCAGATCCCTAGCGAAGATCGTCCACAAAGCGCACAAGGAAGGCGTGTGCGGAGTCAGATCTGTCACT
AGATTGGAGCACCAAATGTGGGAAGCCGTACGGGACGAATTGAACGTCCTGCTCAAAGAGAATGCAGTGG
ACCTCAGTGTGGTTGTGAACAAGCCCGTGGGAAGATATCGCTCAGCCCCTAAACGCCTATCCATGACGCA
AGAGAAGTTTGAAATGGGCTGGAAAGCATGGGGAAAAAGCATTCTCTTTGCCCCGGAATTGGCTAACTCC
ACATTTGTCGTAGATGGACCTGAGACAAAGGAATGCCCTGATGAGCATAGAGCTTGGAACAGCATGCAAA
TCGAAGACTTCGGCTTTGGCATCACATCAACCCGTGTGTGGCTGAAAATTAGAGAGGAGAGCACTGACGA
GTGTGATGGAGCGATCATAGGCACGGCTGTCAAAGGACATGTGGCAGTCCATAGTGACTTGTCGTACTGG
ATTGAGAGTCGCTACAACGACACATGGAAACTTGAGAGGGCAGTCTTTGGAGAGGTCAAATCTTGCACTT
GGCCAGAGACACACACCCTTTGGGGAGATGGTGTTGAGGAAAGTGAACTCATCATTCCGCATACCATAGC
CGGACCAAAAAGCAAGCACAATCGGAGGGAAGGGTATAAGACACAAAACCAGGGACCTTGGGATGAGAAT
GGCATAGTCTTGGACTTTGACTATTGCCCAGGGACGAAAGTCACCATTACAGAGGACTGTGGCAAGAGAG
GCCCTTCGGTCAGAACCACTACTGACAGTGGAAAGTTGATTACTGACTGGTGCTGTCGCAGTTGCTCCCT
TCCGCCCCTACGATTCCGGACAGAAAATGGCTGCTGGTACGGAATGGAAATCAGACCTGTCAGGCATGAT
GAAACAACACTCGTTAGATCACAGGTTGATGCTTTCAATGGTGAAATGGTTGACCCTTTTCAGCTGGGCC
TTCTGGTGATGTTTCTGGCCACCCAGGAGGTCCTTCGCAAGAGGTGGACGGCCAGATTGACCATTCCTGC
GGTTTTGGGGGCCCTACTTGTGCTGATGCTTGGGGGCATCACTTACACTGATTTGGCGAGGTATGTGGTG
CTAGTCGCTGCCGCTTTCGCAGAGGCCAACAGTGGAGGAGACGTCCTGCATCTTGCTTTGATTGCCGTTT
TTAAGATCCAACCAGCGTTTCTAGTGATGAACATGCTTAGCACGAGATGGACGAACCAAGAAAACGTGGT
CCTGGTCCTAGGGGCTGCCTTGTTTCAACTGGCCTCAGTAGATCTGCAAATAGGAGTCCACGGAATCCTG
AATGCCGCCGCTATAGCATGGATGATTGTCCGAGCGATCACCTTCCCCACAACCTCCTCCGTCACCATGC
CAGTCTTAGCGCTTCTAACCCCGGGAATGAGGGCTCTATACCTAGACACTTACAGAATCATCCTCCTCGT
CATAGGGATTTGCTCCCTGCTGCAAGAGAGGAAAAAGACCATGGCAAAAAAGAAAGGAGCTGTACTCTTG
GGCTTAGCGCTCACATCCACTGGATGGTTCTCGCCCACCACTATAGCTGCCGGACTAATGGTCTGCAACC
CAAACAAGAAGAGAGGGTGGCCAGCCACTGAGTTTTTGTCGGCAGTTGGATTGATGTTTGCCATCGTAGG
TGGCTTGGCCGAGTTGGATATTGAATCCATGTCAATACCCTTCATGCTGGCAGGTCTCATGGCAGTGTCC
TACGTGGTGTCAGGAAAAGCAACAGATATGTGGCTTGAACGGGCCGCCGACATCAGCTGGGAGATGGATG
CTGCAATCACAGGAAGTAGTCGGAGGCTGGATGTGAAACTGGATGATGACGGAGATTTTCACTTGATTGA
TGATCCCGGTGTTCCATGGAAGGTCTGGGTCCTGCGCATGTCTTGTATTGGCTTAGCCGCCCTCACGCCT
TGGGCCATCGTTCCCGCCGCTTTCGGTTATTGGCTCACTTTAAAAACAACAAAAAGAGGGGGCGTGTTTT
GGGACACGCCATCCCCAAAACCTTGCTCAAAAGGAGACACTACTACAGGAGTCTACCGAATTATGGCTAG
AGGGATTCTTGGCACTTACCAGGCCGGCGTCGGAGTCATGTACGAGAATGTTTTCCACACACTATGGCAC
ACAACTAGAGGAGCAGCCATTATGAGTGGAGAAGGAAAATTGACGCCATACTGGGGTAGTGTGAAAGAAG
ACCGCATAGCTTACGGAGGCCCATGGAGGTTTGACCGAAAATGGAATGGAACAGATGACGTGCAAGTGAT
CGTGGTAGAACCGGGGAAGGCTGCAGTAAACATCCAGACAAAACCAGGAGTGTTTCGGACTCCCTTCGGG
GAGGTTGGGGCTGTTAGTCTGGATTACCCGCGAGGAACATCCGGCTCACCCATTCTGGATTCTAATGGAG
ACATCATAGGCCTATACGGCAATGGAGTTGAGCTTGGCGATGGCTCATACGTCAGCGCCATCGTGCAGGG
TGACCGTCAGGAGGAACCAGTCCCAGAAGCTTACACCCCAAACATGTTGAGAAAGAGACAGATGACTGTG
CTAGATTTGCACCCTGGCTCAGGGAAGACCAGGAAAATTCTGCCACAGATAATCAAGGACGCCATCCAGC
AGCGCCTAAGAACAGCTGTGCTGGCACCGACGCGGGTGGTAGCAGCAGAAATGGCAGAAGCTTTGAGAGG
GCTCCCAGTGCGATATCAAACTTCAGCAGTGCAGAGAGAGCACCAAGGGAATGAAATAGTGGATGTGATG
TGCCACGCCACTCTGACCCATAGACTGATGTCACCGAACAGAGTGCCCAACTACAACCTATTTGTCATGG
ATGAAGCTCATTTCACTGACCCAGCCAGCATAGCCGCACGAGGATACATTGCTACCAAGGTGGAATTAGG
GGAGGCAGCAGCCATCTTCATGACAGCGACCCCGCCTGGAACCACGGATCCTTTTCCTGACTCAAATGCC
CCAATCCATGATTTGCAAGATGAGATACCAGACAGGGCATGGAGCAGTGGATACGAATGGATCACAGAAT
ATGCGGGCAAAACCGTGTGGTTTGTGGCGAGCGTAAAAATGGGGAATGAGATTGCAATGTGCCTCCAAAG
AGCGGGGAAAAAGGTCATCCAACTCAACCGCAAGTCCTATGATACAGAATACCCAAAATGTAAGAATGGA
GACTGGGACTTTGTCATTACCACCGACATCTCTGAAATGGGGGCCAACTTCGGTGCGAGCAGGGTCATCG
ACTGTAGAAAGAGCGTGAAACCCACCATCTTAGAAGAGGGAGAAGGCAGAGTCATCCTCGGAAACCCATC
TCCCATAACCAGTGCAAGCGCAGCTCAACGGAGGGGCAGAGTAGGCAGAAACCCCAACCAAGTTGGAGAT
GAATATCACTATGGGGGGGCTACCAGTGAAGATGACAGTAACCTAGCCCATTGGACAGAGGCAAAGATCA
TGTTAGACAACATACACATGCCCAATGGACTGGTGGCCCAGCTCTATGGACCAGAGAGGGAAAAGGCTTT
TACAATGGATGGTGAATACCGTCTCAGAGGTGAAGAAAAGAAAAACTTCTTGGAGCTGCTTAGGACGGCT
GACCTCCCGGTGTGGCTGGCCTACAAGGTGGCGTCCAATGGCATTCAGTACACCGACAGAAGGTGGTGTT
TTGATGGGCCGCGCACGAATGCCATACTGGAGGACAACACCGAGGTAGAGATAGTCACCCGGATGGGTGA
GAGGAAAATCCTCAAGCCGAGATGGCTTGATGCAAGAGTTTATGCAGATCACCAAGCCCTCAAGTGGTTC
AAAGACTTTGCAGCAGGGAAGAGATCAGCCATTAGCTTCATAGAGGTGCTCGGTCGCATGCCTGAGCATT
TCATGGGAAAGACGCGGGAAGCTTTAGACACCATGTACTTGGTTGCAACGGCTGAGAAAGGCGGGAAAGC
ACACCGAATGGCTCTCGAAGAGCTGCCAGATGCACTGGAAACCATCACACTTATTGTTGCCATTACTGTG
ATGACAGGAGGATTCTTCCTACTAATGATGCAGCGAAAGGGTATAGGGAAGATGGGTCTTGGAGCTCTGG
TGCTCACGCTAGCTACCTTCTTCCTGTGGGCGGCAGAGGTTCCTGGAACTAAAATAGCAGGGACCCTGCT
GATCGCCCTGCTGCTGATGGTGGTGCTCATCCCAGAACCGGAAAAACAGAGGTCACAGACAGATAACCAA
CTGGCGGTGTTTCTCATCTGCGTCTTGACCGTGGTTGGAGTGGTGGCAGCAAACGAGTACGGGATGCTAG
AGAAAACCAAAGCAGATCTCAAGAGCATGTTTGTCGGAAAGACGCAGGCATCAGGGCTGACTGGATTGCC
AAGCATGGCACTGGACCTGCGTCCAGCCACAGCCTGGGCACTGTATGGGGGGAGCACAGTCGTGCTAACC
CCTCTTCTGAAACACCTGATCACGTCGGAATACGTCACCACATCGCTAGCCTCAATTAACTCACAAGCTG
GCTCATTATTCGTCTTGCCACGAGGCGTGCCTTTTACCGACCTAGACTTGACCGTTGGCCTCGTCTTCCT
TGGCTGTTGGGGTCAAATCACCCTTACAACGTTTCTGACAGCCATGGTTCTGGCGACACTTCATTATGGG
TACATGCTCCCTGGATGGCAAGCAGAAGCACTCAGGGCTGCCCAGAGAAGGACAGCGGCTGGAATAATGA
AGAATGCCGTTGTTGACGGAATGGTCGCCACTGATGTGCCTGAACTGGAAAGGACCACCCCTCTGATGCA
AAAGAAAGTCGGACAGGTGCTCCTCATAGGGGTAAGCGTAGCAGCGTTCCTCGTCAACCCTAATGTCACC
ACTGTGAGAGAAGCAGGGGTATTGGTGACGGCGGCTACGCTCACTTTGTGGGACAATGGAGCCAGTGCCG
TCTGGAATTCCACCACAGCCACGGGACTCTGCCATGTTATGCGAGGTAGCTACCTGGCTGGAGGTTCCAT
TGCTTGGACTCTCATCAAGAACGCGGATAAGCCCTCCTTGAAAAGGGGAAGGCCCGGGGGCAGGACGCTA
GGGGAGCAATGGAAGGAAAAACTAAACGCTATGAGCAGAGAAGAGTTTTTTAAATACCGAAGAGAGGCCA
TAATCGAGGTGGACCGCACTGAAGCACGCAGGGCTAGACGTGAAAACAACATAGTGGGAGGACATCCGGT
TTCGCGAGGCTCAGCAAAACTCCGTTGGCTCGTGGAGAAAGGATTTGTCTCGCCAATAGGAAAAGTCATT
GATCTAGGGTGTGGGCGTGGAGGATGGAGCTACTACGCAGCAACCCTGAAGAAGGTCCAGGAAGTCAGAG
GATACACGAAAGGTGGGGCGGGACATGAAGAACCGATGCTCATGCAGAGCTATGGCCGGAATCTGGTCTC
CTTGAAAAGTGGAGTGGACGTGTTTTACAAACCTTCAGAACCCAGTGACACCCTGTTCTGTGACATAGGG
GAATCCTCTCCAAGTCCAGAAGTAGAAGAACAACGCACACTACGCGTCCTAGAGATGACATCTGACTGGT
TGCACCGAGGACCTAGAGAGTTCTGCATAAAAGTTCTCTGCCCTTACATGCCCAAGGTTATAGAAAAAAT
GGAAGTTCTGCAGCGCCGCTTCGGAGGTGGGCTAGTGCGTCTCCCCCTGTCCCGGAACTCCAATCACGAG
ATGTATTGGGTTAGTGGAGCCGCTGGCAATGTGGTGCACGCTGTGAACATGACCAGCCAGGTACTACTGG
GGCGAATGGATCGCACAGTGTGGAGAGGGCCAAAGTATGAGGAAGATGTCAACCTAGGGAGCGGAACAAG
AGCCGTGGGAAAGGGAGAAGTCCATAGCAATCAGGAGAAAATCAAGAAGAGAATCCAGAAGCTCAAAGAA
GAATTCGCCACAACGTGGCACAAAGACCCTGAGCATCCATACCGCACTTGGACATACCATGGAAGCTATG
AAGTGAAGGCTACTGGCTCAGCCAGCTCTCTCGTCAACGGAGTGGTGAAGCTCATGAGCAAACCTTGGGA
CGCCATTGCCAACGTCACCACCATGGCCATGACTGACACCACCCCTTTTGGACAGCAAAGAGTCTTCAAG
GAGAAAGTTGACACGAAGGCTCCTGAGCCACCAGCTGGAGCCAAGGAAGTGCTCAACGAGACCACCAACT
GGCTGTGGGCCCACTTGTCACGGGAAAAAAGACCCCGCTTGTGCACCAAGGAAGAATTTATAAAGAAAGT
CAACAGCAACGCGGCTCTTGGAGCAGTGTTCGCTGAACAGAATCAATGGAGCACGGCTCGTGAGGCTGTG
GATGACCCGCGGTTCTGGGAGATGGTTGATGAAGAGAGGGAAAACCATCTGCGAGGAGAGTGTCATACAT
GTATCTACAACATGATGGGAAAAAGAGAGAAGAAGCCTGGAGAGTTTGGAAAAGCTAAAGGAAGCAGGGC
CATTTGGTTCATGTGGCTTGGAGCACGGTATCTAGAGTTTGAAGCTTTGGGGTTCCTGAATGAAGACCAT
TGGCTGAGCCGAGAGAATTCAGGAGGTGGAGTGGAAGGCTCAGGCGTCCAAAAGCTGGGATACATCCTCC
GTGACATAGCAGGAAAGCAAGGAGGGAAAATGTACGCTGATGACACCGCCGGATGGGACACTAGAATTAC
CAGAACTGATTTAGAAAATGAAGCCAAGGTGCTGGAGCTCCTAGACGGTGAACACCGCATGCTCGCTCGA
GCCATAATTGAACTGACTTACAGGCACAAAGTGGTCAAGGTCATGAGACCTGCAGCAGAAGGAAAGACCG
TAATGGACGTGATATCAAGAGAAGATCAAAGGGGGAGTGGACAGGTGGTCACTTATGCCCTTAACACTTT
CACGAACATTGCTGTCCAGCTCGTCAGGCTGATGGAGGCTGAGGGGGTCATTGGACCACAACACTTGGAA
CAGCTACCTAGAAAAACCAAGATAGCTGTCAGGACCTGGCTCTTTGAGAATGGAGAGGAGAGAGTGACCA
GGATGGCGATCAGCGGAGATGACTGTGTCGTCAAGCCGCTGGATGACAGATTCGCCACAGCCCTCCACTT
CCTCAACGCAATGTCAAAGGTCAGAAAAGACATCCAGGAATGGAAGCCTTCGCATGGCTGGCACGACTGG
CAGCAAGTTCCCTTCTGCTCTAACCATTTTCAGGAGATTGTGATGAAAGATGGAAGGAGCATAGTTGTCC
CGTGCAGAGGACAGGATGAGCTGATAGGCAGGGCTCGCATCTCTCCAGGAGCTGGATGGAATGTGAAGGA
CACAGCTTGTCTGGCCAAAGCATATGCACAGATGTGGCTACTCCTATACTTCCATCGTAGGGACTTGCGT
CTCATGGCAAATGCGATTTGCTCAGCAGTGCCAGTGGATTGGGTGCCCACAGGCAGGACGTCCTGGTCAA
TACACTCGAAAGGAGAGTGGATGACCACGGAAGACATGCTGCAGGTCTGGAACAGAGTCTGGATTGAAGA
AAATGAATGGATGATGGACAAGACTCCAATCACAAGCTGGACAGACGTTCCGTATGTGGGAAAGCGTGAG
GACATCTGGTGTGGTAGCCTCATCGGAACGCGATCCAGAGCAACCTGGGCTGAGAACATCTATGCGGCGA
TAAACCAGGTCAGAGCTGTCATAGGGAAAGAAAATTATGTTGACTACATGACCTCACTCAGGAGATACGA
AGACGTCCTGATCCAGGAAGACAGGGTCATCTAGTGTGATTTAAAGTAGAAAAGTAGACTATGTAAATAA
TGTAAATGAGAAAATGCATGCATATGGAGTCAGGCCAGCAAAAGCTGCCACCGGATACTGGGTAGACGGT
GCTGTCTGCGTCTCAGTCCCAGGAGGACTGGGTTAACAAATCTGACAACAGAAAGTGAGAAAGCCCTCAG
AACCGTCTCGGAAGTAGGTCCCTGCTCACTGGAAGTTGAAAGACCAACGTCAGGCCACAAATTTGTGCCA
CCCCGCTAGGGGGTGCGGCCTGCGCAGCCCCAGGAGGACTGGGTTACCAAAGCCGTTGAGCCCCCACGGC
CCAAGCCTCGTCTAGGATGCAATAGACGAGGTGTAAGGACTAGAGGTTAGAGGAGACCCCGTGGAAACAA
CAATATGCGGCCCAAGCCCCCTCGAAGCTGTAGAGGAGGTGGAAGGACTAGAGGTTAGAGGAGACCCCGC
ATTTGCATCAAACAGCATATTGACACCTGGGAATAGACTGGGAGATCTTCTGCTCTATCTCAACATCAGC
TACTAGGCACAGAGCGCCGAAGTATGTAGCTGGTGGTGAGGAAGAACACAGGATCT
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