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| Strain Information | Strain Name |
Sendai virus
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|---|---|---|---|---|---|---|---|---|---|
| Strain Family |
Paramyxoviridae
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| RNA Binding Site |
5'UTR - 3'UTR
|
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| Virus Information | Virus Name |
Sendai virus (SV)
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| Taxonomy ID | 11191 | ||||||||
Full list of proteins interacting with the 5'UTR - 3'UTR of this Strain
| Protein Name | Uniprot ID | Host Species | Pro Info | Detection Method | Infection Cell | Cell ID | Cell Originated Tissue | Infection Time | Interaction Score | Fold Change |
|---|---|---|---|---|---|---|---|---|---|---|
| Antiviral innate immune response receptor RIG-I | O95786 | Homo sapiens | Pro Info | . | B95a Cells (Marmoset lymphoblastoid cell line) | . | . | . | . | . |
| Antiviral innate immune response receptor RIG-I | O95786 | Homo sapiens | Pro Info | . | B95a Cells (Marmoset lymphoblastoid cell line) | . | . | . | . | . |
| Interferon-inducible protein 4 | P55265 | Homo sapiens | Pro Info | . | B95a Cells (Marmoset lymphoblastoid cell line) | . | . | . | . | . |
Functional Go Enrichment analysis of those proteins interacting with the 5'UTR - 3'UTR of this Strain
| GO Term | GO Category | GO ID | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|---|
| Double-Stranded RNA Binding | Molecular Function |
GO:0003725
|
0.000135198 | 39870 | 457457.1177 |
| tRNA-specific Adenosine Deaminase Activity | Molecular Function |
GO:0008251
|
0.003899128 | 3332 | 24205.66527 |
| Adenosine Deaminase Activity | Molecular Function |
GO:0004000
|
0.003899128 | 2498.75 | 17524.58157 |
| Ubiquitin-Protein Transferase Activator Activity | Molecular Function |
GO:0097027
|
0.005197947 | 1332.2 | 8576.898814 |
| Single-Stranded RNA Binding | Molecular Function |
GO:0003727
|
0.010776907 | 475.1428571 | 2589.626019 |
| RNA Binding | Molecular Function |
GO:0003723
|
0.010776907 | 37178 | 197174.9945 |
| GTP Binding | Molecular Function |
GO:0005525
|
0.036518153 | 98.99 | 387.2543977 |
| Guanyl Ribonucleotide Binding | Molecular Function |
GO:0032561
|
0.036518153 | 87.88 | 333.5444626 |
| Ubiquitin Protein Ligase Binding | Molecular Function |
GO:0031625
|
0.03729925 | 73.06666667 | 264.1360897 |
| Ubiquitin-Like Protein Ligase Binding | Molecular Function |
GO:0044389
|
0.03729925 | 68.4375 | 243.0315772 |
| Zinc Ion Binding | Molecular Function |
GO:0008270
|
0.039957204 | 57.81764706 | 195.8283924 |
| Transition Metal Ion Binding | Molecular Function |
GO:0046914
|
0.047034498 | 42.95164835 | 133.1197518 |
| Purine Ribonucleoside Triphosphate Binding | Molecular Function |
GO:0035639
|
0.047034498 | 41.10105263 | 125.640737 |
| Bicellular Tight Junction | Cellular Component |
GO:0005923
|
0.035240227 | 248.975 | 1199.537771 |
| Tight Junction | Cellular Component |
GO:0070160
|
0.035240227 | 216.3695652 | 1012.621293 |
| Apical Junction Complex | Cellular Component |
GO:0043296
|
0.035240227 | 189.4571429 | 861.9428221 |
| Actin Cytoskeleton | Cellular Component |
GO:0015629
|
0.08108323 | 60.34355828 | 206.8921049 |
| Cytoskeleton | Cellular Component |
GO:0005856
|
0.109258005 | 32.44147157 | 91.81411946 |
| Nucleolus | Cellular Component |
GO:0005730
|
0.109258005 | 24.97142857 | 64.47858177 |
| Nuclear Lumen | Cellular Component |
GO:0031981
|
0.109258005 | 24.67137356 | 63.42314699 |
| Intracellular Non-Membrane-Bounded Organelle | Cellular Component |
GO:0043232
|
0.144915546 | 15.74874372 | 33.93456932 |
| Nucleus | Cellular Component |
GO:0005634
|
0.442639311 | 3.457868926 | 3.182486159 |
| Intracellular Membrane-Bounded Organelle | Cellular Component |
GO:0043231
|
0.450557627 | 2.865094704 | 2.28425203 |
| Detection Of Virus | Biological Process |
GO:0009597
|
0.007058577 | 4998.5 | 37993.74861 |
| Adenosine To Inosine Editing | Biological Process |
GO:0006382
|
0.007058577 | 3998.6 | 29664.54247 |
| RIG-I Signaling Pathway | Biological Process |
GO:0039529
|
0.007058577 | 3998.6 | 29664.54247 |
| Positive Regulation Of Dendritic Cell Cytokine Production | Biological Process |
GO:0002732
|
0.007058577 | 2855.857143 | 20365.3975 |
| Positive Regulation Of Myeloid Leukocyte Mediated Immunity | Biological Process |
GO:0002888
|
0.007058577 | 1817 | 12220.65208 |
| Positive Regulation Of Granulocyte Macrophage Colony-Stimulating Factor Production | Biological Process |
GO:0032725
|
0.007058577 | 1665.5 | 11068.4336 |
| Cellular Response To Exogenous dsRNA | Biological Process |
GO:0071360
|
0.007058577 | 1537.307692 | 10102.6154 |
| Positive Regulation Of Response To Cytokine Stimulus | Biological Process |
GO:0060760
|
0.007058577 | 1537.307692 | 10102.6154 |
| Regulation Of Granulocyte Macrophage Colony-Stimulating Factor Production | Biological Process |
GO:0032645
|
0.007058577 | 1427.428571 | 9282.083306 |
| Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response | Biological Process |
GO:0061081
|
0.007058577 | 1332.2 | 8576.898814 |
| Regulation Of Response To Cytokine Stimulus | Biological Process |
GO:0060759
|
0.007058577 | 1332.2 | 8576.898814 |
| Cellular Response To dsRNA | Biological Process |
GO:0071359
|
0.007058577 | 1248.875 | 7964.758454 |
| Base Conversion Or Substitution Editing | Biological Process |
GO:0016553
|
0.007058577 | 1248.875 | 7964.758454 |
| Positive Regulation Of Interferon-Alpha Production | Biological Process |
GO:0032727
|
0.008095803 | 998.9 | 6159.553285 |
| Cytosolic Pattern Recognition Receptor Signaling Pathway | Biological Process |
GO:0002753
|
0.008253522 | 908 | 5516.475891 |
| Response To dsRNA | Biological Process |
GO:0043331
|
0.008253522 | 832.25 | 4986.91018 |
| Regulation Of Interferon-Alpha Production | Biological Process |
GO:0032647
|
0.008253522 | 798.92 | 4755.879686 |
| Positive Regulation Of Defense Response To Virus By Host | Biological Process |
GO:0002230
|
0.008394191 | 739.6666667 | 4348.372853 |
| Response To Exogenous dsRNA | Biological Process |
GO:0043330
|
0.00950558 | 587.1764706 | 3320.986753 |
| Positive Regulation Of Interferon-Beta Production | Biological Process |
GO:0032728
|
0.00950558 | 570.3714286 | 3209.886145 |
Functional KEGG Enrichment analysis of those proteins interacting with the 5'UTR - 3'UTR of this Strain
| Pathways | Category | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|
| Cytosolic DNA-sensing pathway | KEGG Pathway | 0.022835104 | 321.5483871 | 1629.854581 |
| Measles | KEGG Pathway | 0.022835104 | 143.9130435 | 615.8516139 |
| Influenza A | KEGG Pathway | 0.022835104 | 115.9473684 | 471.5739863 |
| Coronavirus disease | KEGG Pathway | 0.023065852 | 85.57142857 | 322.5531146 |
Virus RNA Sequence Information
|
>AB039658.1 Sendai virus genomic RNA, complete genome
ACCAAACAAGAGAAGAAACTTGTTTGGAATATATAATGAAGTTAGACAGGATTTTAGGGTCAAAGTATCC
ACCCTGAAGAGCAGGTTCCAGACCCTTAACTTTGCTGCCAAAGTTCACGATGGCTGGGTTGTTGAGCACC
TTCGACACGTTTAGCTCTAGGAGGAGTGAGAGTATTAATAAGTCAGGAGGAGGTGCTGTTATCCCCGGCC
AGAGGAGCACAGTCTCAGTGTTCGTACTAGGCCCAAGTGTGACTGATGATGCAGACAAGTTATTCATTGC
AACCACCTTCTTAGCTCACTCATTAGACACAGATAAGCAGCACTCTCAGAGAGGAGGGTTCCTAGTCTCC
CTACTTGCCATGGCTTACAGTAGTCCAGAATTATACTTGACAACAAATGGAGTAAATGCCGATGTTAAGT
ACGTGATCTACAACATAGAGAAGGACCCTAAGAGGACGAAGACGGATGGATTCATTGTGAAGACAAGGGA
CATGGAATATGAGAGGACCACAGAGTGGCTGTTTGGACCTATGGTCAACAAGAGTCCGCTTTTCCAGGGG
CAACGAGATGCTGCAGACCCTGATACGCTCCTTCAAATCTATGGGTATCCGGCATGCCTAGGGGCAATTA
TTGTCCAGGTCTGGATTGTGCTGGTGAAGGCAATCACGAGTAGTGCCGGCCTAAGGAAAGGATTTTTCAA
TAGATTAGAGGCTTTCAGACAAGATGGCACTGTGAAAGGTGCCTTAGTTTTCACTGGGGAGACAGTTGAG
GGGATAGGCTCGGTCATGCGATCCCAGCAAAGCTTGGTATCTCTCATGGTTGAGACCCTTGTGACTATGA
ACACTGCGAGGTCCGATCTCACTACACTAGAGAAGAACATCCAGATCGTTGGGAACTACATCCGAGATGC
AGGACTAGCCTCTTTCATGAATACCATCAAATATGGGGTAGAGACAAAGATGGCGGCCTTAACGCTGTCA
AACCTGAGGCCCGACATCAACAAGCTGAGAAGCCTCATAGACACCTACCTGTCAAAAGGACCCAGGGCTC
CTTTTATTTGTATCCTAAAGGACCCTGTCCATGGTGAGTTTGCACCAGGCAACTATCCAGCACTCTGGAG
CTATGCAATGGGAGTCGCCGTTGTACAGAACAAGGCGATGCAGCAGTACGTCACAGGGAGAACATACCTT
GATATGGAGATGTTCTTACTAGGACAAGCTGTAGCAAAGGACGCTGAGTCCAAGATCAGCAGTGCTCTGG
AGGACGAGCTAGGAGTGACAGATACGGCTAAGGAGAGGCTCAGACATCATTTGGCAAATCTGTCCGGTGG
GGATGGCGCGTACCACAAGCCAACAGGCGGCGGTGCAATCGAGGTAGCTCTAGACAATGCCGACATAGAC
CTGGAGCCTGAAGCTCACACAGATCAGGACGCCAGAGGTTGGGGTGGGGATAGCGGTGACAGATGGGCTC
GCTCGACGAGTAGTGGCCACTTTATCACACTACATGGGGCAGAACGGTTGGAGGAGGAGACCAATGATGA
AGATGTCTCCGACATAGAGAGAAGAATAGCTAGGAGGCTTGCAGAGAGACGGCAAGAGGACGCTACAACC
CACGAAGACGAAGGCCGTAATAACGGTGTTGATCATGACGAAGAGGATGATGCCGCGGCAGCAGCTGGGA
TGGGAGGAATCTAAGATCACACGAGGATTTAGGATACATGACCCGTAGTAAGAAAAACTTAGGGTGAAAG
CTCATCCACCGATCCGCCCAGACCAGGCCACATCCAACTCCATTGACTACGCCCAGCAGTCCAGACAACC
ACGGCTTCGGCTACACTTCCCGCATGGATCAAGATGCCCTCATTTCTAAAGAAGATTCTGAAGTTGAGAG
GGAGGCGTCAGGAGGACGAGAGTCGCTCTCGGATGTTATCGGATTCCTCGACGCAGTCCTATCAAGTGAA
CCAACTGACATCGGAGGAGACAGAAGCTGGCTCCACAATACCATCAACACCCTCCAAAGGCCAGGCTCTA
CCCACAGAGCCAAAGGTGAGGGCGAGGGAGAAGTCTCGACATCGTCGACCCAAGATAATCGATCAGGTGA
GGAGAGTAGAGTCTCTGGGGGAACAAGCGAGCCAGAGGCAGAAGCACATGCTAGAAACGTTGATAAACAA
AATATACACTGGGCCACTGGGAGAGGAGCTAGTACAGACTCTGTACCTCAGGATCTGGGCAATGGAAGAG
ACTCCGGAATCCTTGAAGATCCTCCAAATGAGGGAGGATATCCGAGATCAGGTGCTGAAGATGAAAACCG
AGAGATGGCTGCGAACCCTGATAAGAGGGGAGAAGACCAAGCTGAAGGACTTCCAGAAGAGATACGAAGA
AGTGCACCCCTACCTGATGAAGGAGAAGGTAGAGCAGATAATAATGGAAGAGGCGTGGAGTCTGGCAGCC
CACATAGTGCAAGAGTGACTGGAGTCTTGGTGATCCCCAGTCCTGAGCTCGAAGAGGCCGTGCTACAAAG
GAACAAGAGACGACCCGCCAACAGCGGGTCCAGATCTCTCACCCCAGTGGTCGTGCCTAGCACTCGGTCT
CCACCACCGGACCATGACAATAGTACAAGGTCACCACCAAGGAAACCCCCAACCACGCAGGATGAGCACA
CCAACCCCAGGAACACCCCCGCCGTCAGGATCAAGGATCGGAGACCCCCAACAGGGACTCGCTCCGCCCC
AGACCGCCCGACCGACGGCTATCCAACCCACCCAGGTCCAGAGACCGACGCAACAAAAAAGGGCATAGGA
GAGAACACATCATCTATGAAAGAGATGGCTACATTGTTAACGAGTCTTGGTGTAATCCAGTCTGCTCAAG
AATTCGAGTCATCTCGAGACGCGAGTTATGTGTTTGCAAGGCGTGCCCTAAAATCTGCAAACTATGCAGA
GATGACATTTAATGTATGCGGCTTGATCCTTTCTGCTGAGAAATCTTTCGCCAATAGAGTAGACGAGAAT
AAACAGCTGCTTAAACAGATCCAAGAAAGTGTAGAGTCATTTCGGGACATATACAAGAGATTCTCTGAGT
ATCAGAAGGAACAGAACTCACTGCTGATGTCTAACCTATCTACACTTCATATTATCACAGACAGAGGTGG
CAAGACTGACAATCCAGATTCTCCCACAAGGTCCCCCTCTGTTTTTGCAAAAACAAAAGAGAACAAGACC
AAAGCAACTAGGTTTGACCCGTCTATGGAGACCATGGGGGATATGAAGTATAAACCAGACCTACTCCGAG
AGGATGAATTTAGAGATGAGATCCGCAACCCGGTGTACCAGGAAAGAGATACCGAACCCAGAGCATCCAA
TGCATCACGTCTGCTTCCATCAAGAGAGAAGCCTACAATACACTCCCTCAGGCTCGTCATAGAGAGCAGT
CCCCTAAGCAGAGCTGAAAAGGCAGCATATGTGAAATCATTATCCAAATGCAAGACAGACCAAGAGGTTA
AGGCAGTCATGGAGCTTGTAGAAGAAGACATAGAATCACTGACTAATTAAGAACTAGGTGAGGCATCTAA
TCATCCTCAGTAGTGGAGCGACCTAATTCATCATTAGCATCAGCCAGTAGAGATTAAGAAAAACTTAGGG
TGAAAGAAATTTCACCTAATAAGATACAATGGCCGACATCTATAGATTCCCCAAGTTCTCATATGAGGAT
AACGGTACTGTAGAGCCTCTGCCTCTGAGAACTGGTCCGGATAAGAAGGCCATCCCTCATATCAGGATTG
TCAAGGTAGGAGACCCTCCAAAGCATGGAGTGAGATACCTAGATTTATTGCTCTTAGGCTTCTTTGAGAC
GCCGAAGCAAACGGCCAGCTTAGGGAGTGTGTCCGACCTGACAGAGCACACCGGCTACTCAATCTGTGGC
TCCGGATCGTTACCCATAGGTGTAGCTAAATACCACGGGTCTGATCAGGAACTCTTAAAGGCCTGCACTG
ATCTCAGAATTACAGTGAGGAGGACTGTTCGAGCAGGGGAGATGATAGTATACATGGTGGATTCGATCGG
TGCTCCACTCCTACCATGGTCGGGCAGGCTGAGACAGGGAATGATATTTAATGCCAACAAGGTCGCGCTT
GCCCCCCAGTGCCTCCCGGTGGACAAGGACATAAGATTCAGAGTGGTGTTTGTCAATGGGACATCCCTGG
GGGCGATCACTATAGCCAAGATCCCAAAGACTCTTGCAGACCTTGCATTGCCTAATTCTATCTCTGTTAA
CCTACTAGTGACACTCAAGACCGGGATCCCCACGGAGCAAAAGGGGGTACTCCCAGTACTCGATGATCAA
GGAGAGAAGAAGCTCAATTTTATGGTGCATCTTGGGTTGATCAGAAGAAAAGTCGGGAAGATATACTCCG
TTGAGTACTGCAAGAGCAAGATCGAGAGGATGCGGCTGATCTTCTCACTTGGGTTAATTGGCGGCATAAG
CTTCCATGTCCAGGTCACTGGGACCCTATCTAAGACATTCATGAGCCAGCTCGCATGGAAAAGAGCGGTC
TGCTTCCCATTGATGGACGTGAATCCTCATATGAACCTGGTGATTTGGGCGGCGTCTGTTGAGATCACAG
ACGTTGATGCGGTTTTCCAGCCGGCCATCCCTCGTGATTTCCGCTACTACCCTAATGTCGTGGCAAAGAA
CATAGGGAGGATCAGGAAGCTGTAAATGTGCATCCATCAGGGACCTACGACAATGCCTAGAGCAGACACC
ACTTGGCAGCCGGAGCCATAGCATTGCTCTTTGTATTAAGTAAGAAAAACTTAGGGATAAAGTCCCTTGC
GCGTGCCCTGTCGTAGAACTTTCCTTTTGGGGAAAATGGCGACTTATATCCAGAGGGTACAGTGCATATC
TGCATTATTGTCAGTTGTGCTCACAACACTGGTCTCGTGTCAAATTCCTAGAGATAGGCTCTCTAATATA
GGGGTCATAGTCGACGAAGGGAAATCACTGAAGATTGCCGGGTCCCACGAATCTAGGTACATCGTATTAA
GTCTGGTCCCAGGGGTAGACCTCGAAAATGGGTGCGGAACAGCTCAGGTTATCCAGTATAAGAGCCTACT
GAACCGGTTGTTAATCCCATTGAGAGATGCCTTAGATCTTCAGGAGGCTCTGATAACTGTCACTAATGAC
ACGATGACCAGTGCTGATGTCCCACAGTCAAGATTCTTCGGCGCCGTGATTGGGACCATAGCACTTGGAG
TGGCAACATCAGCACAGATAACCGCAGGGATCGCGCTAGCTGAGGCGAGGGAGGCCAAGAGAGACATAGC
ACTCATAAAAGAATCAATGACAAAGACACACAAATCTATAGAACTGCTGCAAAACGCTGTGGGGGAACAA
ATTCTTGCTCTAAAGACGCTCCAGGATTTCGTGAATGATGAGATCAAACCCGCGATAAGCGAATTGGGTT
GTGAGACTGCCGCTTTAAGACTGGGGATAAAACTGACACAACATTACTCCGAGCTGCTGACTGCATTTGG
CTCTAACTTTGGAACCATCGGAGAGAAGAGCCTCACACTGCAGGCACTGTCTTCACTCTACTCTGCTAAC
ATCACTGAGATTATGACCACGATCAGGACAGGGCAGTCCAACATCTATGACGTCATTTATACGGAGCAGA
TCAAGGGAACTGTGATTGATGTAGATCTAGAGAGATACATGGTTACCCTGTCTGTGAAAATCCCCATTCT
TTCTGAAGTTCCAGGTGTGCTTATACACAAGGCATCGTCTATTTCTTACAATATAGACGGGGAGGAGTGG
TATGTGACTGTCCCCAGTCACATACTCAGTCGTGCCTCCTTCCTGGGGGGTGCAAACATAGCTGATTGTG
TAGAGTCCAGATTGACCTACATATGCCCTAGGGATCCTGCACAATTGATACCTGACAGCCAGCAAAAATG
TATCTTGGGGGACACAACAAGGTGTCCTGTCACAAAGGTTGTGGATAACCTCATCCCCAAATTTGCCTTT
GTAAATGGAGGTGTCGTCGCGAACTGCATAGCATCCACATGTACCTGCGGGACAGGCCGAAGGCCAATCA
GTCAGGATCGCTCTAAAGGTGTAGTATTCTTAACTCATGATAACTGTGGACTCATAGGAGTCAATGGGAT
AGAATTGTATGCTAATAGGAAAGGGCATGATGCCACTTGGGGGGTCCAGAATTTGACAGTCGGTCCTGCA
ATCGCTATCAGACCCGTGGACATTTCTCTCAACCTTGCCGCTGCTACTGACTTCCTGCAAGACTCTAGAG
CTGAACTTGAGAAGGCACGAAAAATCCTCTCTGAAGTAGGTAGATGGTACAATTCAGGGGCGACTTTGAT
TACGATCATAGTAGTCATGATTGTAGTATTGGTGGTCATTATAGTGATTGTCATTGTGCTCTACAGACTC
AGGAGATCAATGCTAATGAGTAATCCAGCCGGTCGGATATCAAGAGACACATATACATTAGAGCCGAAGA
TAAGGCATATGTATACTAACGGTGGGTTCGATGCTATGACTGAGAAAAGATGACCATAACTCTTGTTAGA
TATTTGGTAAAGCAGGTATGGTATTTGCTGAGGTCTGTACATAATAAGAAAAACTTAGGGTGAAAGTTAG
GTTGCTCACCACTATAGCTTTCACCTCAAATAAGTACAGATCATGGATGGTGACAGAAGCAAGCGGGACT
CGTACTGGTCTACCTCCCCTGGTGGTAGCACTACAAAATTGGTGTCAGACTCAGAGAGGTCAGGTAAAGT
TGATACCTGGCTATTGATTCTCGCATTCACCCAATGGGCTTTGTCAATTGCCACGGTTATCATTTGCATC
GTAATCGCTGCTAGGCAAGGGTATAGTATGGAAAGATATTCAATGACCGTGGAGGCACTAAACACAAGCA
ACAAAGAAGTGAAGGAGTCACTCACTAGTCTAATAAGGCAAGAGGTTATCACTAGAGCCGTTAACATTCA
GAGTTCTGTGCAAACCGGGATCCCAGTCTTGTTGAACAAGAACAGCAGAGATGTCATCCAGCTGATTGAA
AAGTCGTGCAATAGACAGGAGCTCACGCAACTTTGCGATAGCACAATTGCAGTCCATCATGCTGAGGGAA
TTGCCCCACTTGAACCGCATAGCTTCTGGAGATGCCCTGCAGGAGAACCGTATCTAAGTTCAGACCCTGA
AGTCTCATTGCTGCCTGGCCCAAGCCTGTTGTCTGGTTCGACAACGATCTCTGGATGTGTTAGGCTCCCT
TCACTCTCAATTGGTGAGGCGATCTATGCCTATTCGTCAAATCTCATTACACAAGGCTGTGCTGACATAG
GGAAGTCATATCAGGTCCTGCAGCTAGGGTATATATCACTAAATTCAGATATGTTTCCTGACCTTAACCC
CGTAGTGTCCCACACTTATGACATCAACGACAACCGGAAATCGTGCTCGGTAGTGGCAACCGGGACCAGG
GGTTATCAGCTCTGCTCCATGCCGACTGTAGACGAAAGAACTGACTACTCGAGTGATGGTATCGAAGATT
TGGTCCTTGACATTCTGGATCTTAAAGGGAGGACTAAATCTCATCGGTATAGCAACAGTGAGATAGATCT
TGACCACCCGTTTTCTGCATTATACCCTAGTGTGGGCAGCGGCATTGCAACAGAGGGTTCACTGATATTC
CTTGGGTATGGTGGGCTAACCACCCCGCTACAAGGTGATACGAAATGTAGGATCCAAGGATGCCAACAGG
TGTCGCAAGACACATGCAATGAAGCTCTGAAGATTACATGGCTGGGCGGGAAACAGGTAGTCAGTGTGCT
CATCCAGGTTAATGATTATCTTTCAGAGAGACCAAGAATAAGAGTCACAACCGTTCCAATCACTCAGAAC
TACCTCGGAGCAGAAGGCAGATTACTAAAATTGGGTGATCAAGTGTACATCTACACGAGATCATCAGGTT
GGCATTCCCAACTGCAGATAGGGGTACTTGATGTCAGCCACCCTCTGACTATCAGCTGGACACCCCATGA
AGCCTTGTCTAGGCCAGGAAACGAAGACTGCAATTGGTACAATACTTGTCCGAAGGAATGCATATCAGGT
GTATATACCGACGCTTATCCCCTGTCTCCTGATGCAGCTAATGTAGCCACCGTTACGTTGTATGCCAACA
CTTCACGCGTCAATCCAACAATCATGTATTCCAACACCACTAACATTATAAATATGTTAAGGATAAAAGA
TGTCAAATTAGAGGCTGCATATACCACGACATCATGTATCACGCACTTTGGCAAAGGCTACTGTTTCCAC
ATCATCGAGATCAACCAAAAGAGCTTGAACACCCTGCAACCTATGCTCTTTAAGACCAGCATTCCGAAGT
TATGCAAGGCCGAGTCGTGAATTTCACCGATCAACAGGCTAGTCGGCTCTGCCGACACAGGGGTCATCAC
TGGATACCCACAACATCTCCTAGTCTCTCACATTCTCCACAGTATTAAGAAAAACCCAGGGTGAATGGGA
AGCCTGTCATTGGCTATGGACGGGCAAGAGTCCTCCCAAAACCCTTCTGACATACTCTATCCAGAATGTC
ACCTGAACTCCCCTATAGTGAGGGGAAAGATAGCACAATTACACGTTTTGTTAGATGTTAACCAGCCCTA
CATTCTGAAAGACGACAGTATAATTAATATCACAAAGCACAAAATCAGGAATGGGGGTTTGTCCCCTCGT
CAGATTAAGATCAGATCTCTAGGCAAGGCTCTTCAACGCACAATAAAGGATCTAGACCGGTACACGTTTG
AACCGTACCCAACCTACTCCCAGGAGTTACTTAGGCTCGATATACCAGAGATATGTGACAAGATCCGATC
TGTTTTCGCGGTCTCGGATCGGCTGACTAAGGAGCTGTCTAATGGGTTCCAGGATCTCTGGTTGAATATC
TTTAAGCAACTAGGTAACATAGAAGGGAGAGAGGGGTACGACCCATTGCAGGATATTAGCACCATCCCAG
AGATAACTGAGAGGTATAGCAGGAACAAATGGTATAGGCCATTCCTAACTTGGTTCAGTATCAAATATGA
TATGCGGTGGATGCAGAAAACTAGACCAGGGGGACCTCTAGATACCTCTAACTCACATAACCTTCTAGAA
TGCAAATCATACACTCTAGTAACATATGGAGACCTTGTCATGATACTGAACAAGTTGACATTGACAGGGT
ATATCCTAACACCTGAGCTGGTTCTGATGTATTGTGATGTTGTGGAAGGGAGGTGGAATATGTCTGCTGC
AGGGCAGTTAGATAAAAGGTCTACTGGGATAACAAGCAAAGGAGAGGAGTTATGGGAGTTAGTGGATTCC
CTCTTTTCGAGTCTCGGGGAGGAAATATACAATGTCATCGCATTACTCGAGCCTCTATCACTTGCTCTCA
TACAATTAAGTGATCCTGTTATACCTCTACGTGGAGCATTTATGAGGCATGTGTTGACAGAGCTACAGAC
TGTTTTGACGAGTAAAGACGTGTATACGGACCCGGAGGCAGATGCTATTGTGGAGTCGTTACTAGCTATA
TTTCATGGGACTTCTATTGATGAGAAAGCAGAGATCTTTTCATTCTTTCGGACATTCGGTCATCCTAGCT
TGGAAGCTGTCACCGCTGCCGACAAGGTGAGAGCTCATATGTATGCACAAAAGGCAATAAAGCTTAAGAC
CCTACACGAGTGTCATGCAGTGTTCTGCACAATCATCATAAATGGATATAGAGAGAGGCATGGCGGGCAG
TGGCCCCCTTGCGACTTCCCTGATCACGTGTGCCTGGAACTTAGAAATGCTCAAGGGTCCAATACGGCCA
TCTCTTACGAGTGTGCAGTAGACAACTATACAAGTTTCATAGGCTTCAAGTTTCGGAAGTTTATAGAACC
ACAACTGGATGAAGATCTCACGATATATATGAAGGACAAAGCATTATCGCCCAGGAAGGAAGCGTGGGAC
TCTGTGTATCCAGACAGTAACCTGTACTATAAAGTTCCAGAGTCTGAAGAGACCAGGAGGCTCATCGAAG
TGTTCATAAATGATGAGAATTTCAACCCAGAAGACATCATCGATTACGTGGAGTCAGGAGACTGGTTAAA
AGATGAGAAGTTCAACATCTCGTATAGTTTGAAAGAGAAAGAGATCAAGCAAGAGGGCCGTCTGTTCGCA
AAGATGACTTACAAAATGCGAGCTGTACAGGTCCTAGCAGAGACACTGTTGGCGAAAGGAATAGGAGAGT
TGTTCAGCGAAAATGGAATGGTGAAAGGAGAGATAGACTTACTTAAAAGACTAACTACTCTCTCTGTCTC
AGGAGTTCCTAGGACTGATTCAGTGTACAATAATCCTAGATCATCAGAGAAGAGAAATGAAGGCATGAAG
AAGAGAAACTCAAAAGGGTACTGGGACGAAAAGAAGAGGTCGAGACATGAATTTAAAGCAACAGATTCAT
CCACAGACGGTTATGAGACGTTAAGTTGCTTCCTAACAACAGACCTCAAGAAGTACTGCTTAAATTGGAG
ATTTGAGAGCACTGCACTTTTCGGGCAGAGGTGCAACGAGATATTTGGCTTCAAGACCTTTTTCAATTGG
ATGCATCCAGTCCTTGAAAAGTGTACAATATATGTTGGAGACCCTTACTGTCCGGTCGCCGACAGGATGC
ATCGACAACTGCAAGATCATGCAGACTCTGGTATTTTCATACACAATCCTAGGGGAGGAATAGAAGGTTA
TTGCCAGAAACTATGGACCTTAATCTCAATCAGTGCGATCCACCTAGCAGCTGTGAGGGTAGGTGTCAGG
GTCTCTGCAATGGTTCAAGGCGACAATCAAGCTATAGCAGTAACATCAAGAGTACCCGTAGCCCAGACTT
ACAAGCAGAAGAAAAATCATGTCTATGAAGAGATCACTCGTTATTTCGGTGCTCTAAGACATGTCATGTT
TGATATAGGACATGAGCTAAAATTGAACGAGACCATCATTAGTAGTAAAATGTTTGTCTATAGTAAAAGG
ATATATTATGATGGAAAGATCCTACCGCAATGTCTGAAGGCCTTGACTAGATGTGTATTCTGGTCCGAGA
CATTGGTTGATGAGAACAGATCTGCTTGTTCCAATATCTCAACATCCATAGCAAAGGCCATCGAGAATGG
GTATTCTCCTATACTAGGCTACTGCATTGCGTTGTACAAGACCTGTCAGCAAGTGTGTATATCATTAGGG
ATGACTATAAATCCAACAATCAGCCCGACCGTAAGAGATCAATACTTTAAGGGTAAAAATTGGCTGAGAT
GTGCAGTGTTAATTCCGGCCAATGTTGGGGGATTCAACTACATGTCTACATCTAGGTGCTTTGTCAGGAA
TATTGGGGATCCGGCAGTCGCAGCCCTAGCTGATCTCAAGAGATTCATCAGAGCAGATCTTCTAGATAAA
CAGGTGTTGTATAGGGTCATGAATCAAGAGCCTGGTGATTCTAGTTTTCTAGATTGGGCTTCAGATCCTT
ATTCATGCAACCTTCCGCACTCTCAGAGTATAACTACAATTATAAAGAATATCACTGCTAGGTCTGTGCT
GCAGGAATCTCCGAATCCTCTACTGTCTGGTCTTTTTACAGAGACCAGTGGCGAAGAGGATCTCAACCTG
GCCTCGTTTCTTATGGACCGGAAAGTCATCCTACCTAGAGTGGCTCATGAGATCTTGGGTAATTCCTTAA
CAGGGGTTAGAGAAGCAATTGCAGGGATGCTTGATACAACCAAGTCTCTAGTGAGAGCGAGTGTTAAGAG
GGGAGGATTGTCATATGGGATATTGAGGAGACTTGTCAATTATGATCTGTTGCAGTACGAGACACTGACT
AGGACTCTCAGGAAGCCGGTGAAAGACAACATTGAGTATGAGTATATGTGCTCAGTTGAGCTGGCTGTCG
GTTTAAGGCAGAAGATGTGGATCCACCTGACGTATGGGAGACCTATACACGGGCTAGAAACACCAGACCC
TTTAGAGCTCTTGAGGGGAACATTTATTGAAGGCTCAGAGGTGTGTAAGCTTTGCAGGTCTGAGGGAGCG
GACCCCATCTATACATGGTTTTACCTCCCAGACAATATAGACCTGGATACACTTACAAACGGGAGTCCAG
CTATACGGATTCCCTATTTTGGATCAGCAACTGATGAAAGATCAGAAGCTCAACTCGGATATGTAAGGAA
TCTGAGTAAACCAGCAAAGGCGGCTATACGGATAGCTATGGTGTACACGTGGGCTTACGGGACCGATGAG
ATATCGTGGATGGAAGCTGCTCTCATAGCCCAGACAAGGGCTAATCTGAGCTTAGAAAATCTAAAGCTGC
TGACTCCTGTTTCAACATCAACTAATCTCTCTCATAGGTTAAAAGACACGGCAACCCAGATGAAGTTCTC
CAGTGCAACACTAGTCCGTGCAAGTCGGTTCATAACAATATCAAATGACAACATGGCACTCAAAGAAGCA
GGGGAGTCGAAGGACACTAATCTCGTATATCAGCAGATTATGCTCACTGGGCTAAGCTTGTTTGAGTTCA
ATATGAGGTATAAGAAAGGTTCCTTAGAGAAGCCACTGATATTACACCTACATCTTAATAACGGGTGCTG
TATAATGGAATCTCCACAGGAAGCAAATATCCCCCCAAGATCCACTTTGGATTTGGAAATCACACAAGAA
AACAACAAATTGATCTATGATCCCGATCCACTCAGGGATGTAGACCTAGAGCTATTTAGCAAGGTCAGAG
ATGTCGTACATACAGTTGACATGACCTATTGGTCAGACGATGAAGTTATCAGGGCTACTAGTATATGTAC
TGCAATGACAATAGCTGATACAATGTCTCAATTAGATAGAGACAACTTAAAGGAGATGATAGCACTGGTA
AATGATGATGATGTCAACAGCCTGATTACTGAGTTTATGGTGATTGATGTTCCTCTATTTTGCTCAACAT
TCGGAGGTATCCTAGTCAATCAGTTTGCATACTCACTCTACGGCTTGAATATCAGAGGAAGGGAAGAAAT
ATGGGGACACGTAGTCCGGATTCTGAAAGATACCTCCCACGCAGTCTTGAAAGTCTTATCCAATGCTCTG
TCCCATCCCAAGATCTTCAAACGATTCTGGAATGCAGGTGTTGTAGAACCTGTGTATGGGCCTAACCTTT
CAAATCAGGATAAGACACTACTAGCCCTCTCTGTATGTGAGTATTCTGTGGACCTATTCATGCACGACTG
GCAAGGAGGTGTACCGCTTGAGGTCTTTATCTGTGATAATGACCCAGATGTGGCTGACATGAGGAGGTCC
TCTTTCTTGGCTAGACACCTTGCATACCTGTGCAGCTTGGCAGAGATATCTAGGGATGGGCCAAGACTAG
AGTCAATGAACTCTCTTGAGAGGCTAGAGACATTAAAGAGTTATCTGGAACTCACGTTCCTTGATGACCC
TGTACTGAGGTACAGTCAATTGACTGGCTTAGTCATCAAAGTATTCCCGTCAACTTTGACCTACATCCGG
AAGTCATCTATAAAGGTATTAAGAACAAGAGGAATAGGAGTCCCCGAAGTTTTAGAAGATTGGGACCCCG
AGGCGGATAATGCACTGCTAGACGGCATCGCAGCAGAAATACAACAGAATATTCCCTTAGGACATCAGAC
TAGAGCCCCTTTTTGGGGGCTGAGGGTATCCAAGTCACAGGTACTGCGTCTCCGGGGGTACGAGGAGATC
ACAAGAGGTGAGGTAGGCAGATCAGGTGTTGGTCTGACGTTACCATTCGATGGAAGGTATCTATCTCACC
AGCTGAGGCTCTTTGGTGTTAACAGTACTAGCTGCTTAAAAGCACTTGAACTTACCTACTTATTAAGCCC
CTTGGTTGACAAGGATAAGGATAGGCTGTTTTTAGGGGAAGGAGCTGGGGCTATGCTCTCCTGTTATGAC
GCTACTCTTGGCCCATGCATCAACTATTATAACTCGGGGGTATACTCTTGTGATGTCAATGGGCAGAGAG
AGTTAAATATATATCCTGCTGAAGTGGCATTAGTGGGAAAGAAATTAAATAATGTTACCAGTCTAGGTCA
GAGGGTTAAGGTGTTGTTCAACGGGAATCCTGGCTCGACATGGATCGGGAATGATGAATGTGAGGCTTTG
ATTTGGAATGAACTACAGAATAGTTCGATAGGCCTAGTCCACTGTGACATGGAAGGAGGAGATCATAAGG
ATGATCAAGTTGTACTGCATGAGCATTACAGTGTGATCAGGATTGCGTATCTGGTGGGGGATAGAGACGT
TGTGCTGATAAGTAAGATTGCTCCCAGGCTGGGCACAGATTGGACCAGGCAGCTTAGCCTTTACCTGAGG
TACTGGGATGAGGTCAACCTGGTAGTGCTTAAAACATCTAATCCTGCTTCTACAGAGATGTATCTCCTCT
CAAGGCATCCCAAATCTGACATCATAGAAGATAGCAAGACAGTGCTGGCCAGTCTTCACCCTCTGTCAAA
GGAAGACAGCATCAAGATAGAAAAGTGGATCTTGATAGAGAAAGCAAAGGCTCACGAATGGGTTACCCGG
GAGTTGAGAGAAGGAAGCTCGTCGTCAGGGATGCTTAGACCTTACCACCAGGCACTGCAGACGTTTGGTT
TTGAACCCAATTTATATAAACTGAGCAGGGATTTCCTGTCCACTATGAACATAGCTGACACTCACAACTG
CATGACAGCCTTCAACAGAGTTTTAAAGGATACAATCTTTGAGTGGGCTAGAATAACCGAGTCAGACAAA
AGGCTCAAACTAACTGGTAAGTATGACCTGTACCCTGTTAGAGACTCAGGCAAGTTGAAGACAATTTCTA
GAAGACTTGTACTGTCTTGGGTATCATTATCTATGTCTACAAGACTGGTAACTGGGTCTTTCCCCGACCA
AAAGTTTGAGGCAAGACTCCAATTAGGGATAGTTTCACTGTCATCTCGTGAAATCAGGAACCTGAGGGTT
ATCACAAAAACTATATTAGATAGGTTTGAGAATACTATACATAGTATAACATATAGATTTCTCACCAAAG
AAATAAAGATTTTGATGAAGATTTTAGGAGCTGTCAAGATGTTCGGGGCTAGGCAGAATGAATACACAAC
CGTGGTTGATGATGGATCATTAGATGACATCGAGCCATATGACAGCTTGTGATAAGTAATCATTATCATG
CAGGGTTATTTAAAATTCACGGTGTCTAGAAGTCTTGGACTTATCCATATGGCAATAGTAAGAAAAACTT
ACAAGGAGACAAGAAAATTTGAAAGAATAAATATCTCTTAAACTCTTGTCTGGT
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