Host Protein General Information

  Protein Name
Steroid 17-alpha-hydroxylase/17,20 lyase
  Gene Name
CYP17A1
  Host Species
Homo sapiens
  Uniprot Entry Name
CP17A_HUMAN
  Protein Families
Cytochrome P450 family
  EC Number
1.14.14.19; 1.14.14.32
  Subcellular Location
Endoplasmic reticulum membrane
  External Link
NCBI Gene ID
1586
Uniprot ID
P05093
Ensembl ID
ENSMUSG00000034459
HGNC ID
2593
  Related KEGG Pathway
Steroid hormone biosynthesis hsa00140            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Ovarian steroidogenesis hsa04913            Pathway Map 
Prolactin signaling pathway hsa04917            Pathway Map 
Cortisol synthesis and secretion hsa04927            Pathway Map 
Cushing syndrome hsa04934            Pathway Map 
  3D Structure
PDB ID: 3RUK 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ABIRATERONE . 132971  D02STN  DGIdb
ABIRATERONE ACETATE . 9821849  D06CNP  DGIdb
abiraterone acetate . 9821849  D06CNP  DrugCentral
bifonazole . 2378  D0AA2D  DrugCentral
clotrimazole . 2812  D09GOS  DrugCentral
econazole . 3198  D0EV8E  DrugCentral
GALETERONE . 11188409  D0U0BU  DGIdb
isoconazole . 3760  D0GJ7J  DrugCentral
ketoconazole . 456201  D0B4IF  DrugCentral
levoketoconazole . 47576  D0ES9U  .
miconazole . 4189  D00AXJ  DrugCentral
ORTERONEL . 9883029  D0X3OI  DGIdb
SEVITERONEL . 78357816  D0Q9KR  DGIdb
testosterone propionate . . . DrugCentral
tioconazole . 5482  D0CA6J  DrugCentral
ZYTIGA . 9821849  D06CNP  DGIdb

Protein Sequence Information

MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQAEGST
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