Host Protein General Information

  Protein Name
Fumarate hydratase
  Gene Name
FH
  Host Species
Homo sapiens
  Uniprot Entry Name
FUMH_HUMAN
  Protein Families
Class-II fumarase/aspartase family, Fumarase subfamily
  EC Number
4.2.1.2
  Subcellular Location
Mitochondrion
  External Link
NCBI Gene ID
2271
Uniprot ID
P07954
Ensembl ID
ENSG00000091483
HGNC ID
3700
  Related KEGG Pathway
Pathways in cancer hsa05200            Pathway Map 
Renal cell carcinoma hsa05211            Pathway Map 
Citrate cycle (TCA cycle) hsa00020            Pathway Map 
Pyruvate metabolism hsa00620            Pathway Map 
Cushing syndrome hsa04934            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Carbon metabolism hsa01200            Pathway Map 
  3D Structure
PDB ID: 3.00E+04 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 5'UTR - 3'UTR RNA Info Genome-wide RNA interference (RNAi) screen HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
DITIOCARB . . . DGIdb

Protein Sequence Information

MYRALRLLARSRPLVRAPAAALASAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK
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