Host Protein General Information

  Protein Name
Thrombospondin-1
  Gene Name
THBS1
  Host Species
Homo sapiens
  Uniprot Entry Name
TSP1_HUMAN
  Protein Families
Thrombospondin family
  Subcellular Location
Secreted
  External Link
NCBI Gene ID
7057
Uniprot ID
P07996
Ensembl ID
ENSG00000137801
HGNC ID
11785
  Related KEGG Pathway
Malaria hsa05144            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
Proteoglycans in cancer hsa05205            Pathway Map 
MicroRNAs in cancer hsa05206            Pathway Map 
Bladder cancer hsa05219            Pathway Map 
p53 signaling pathway hsa04115            Pathway Map 
Focal adhesion hsa04510            Pathway Map 
Rap1 signaling pathway hsa04015            Pathway Map 
PI3K-Akt signaling pathway hsa04151            Pathway Map 
TGF-beta signaling pathway hsa04350            Pathway Map 
ECM-receptor interaction hsa04512            Pathway Map 
Phagosome hsa04145            Pathway Map 
  3D Structure
PDB ID: 1LSL 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ABT-510 . 6918562  D0G4MB  DGIdb
CAMPTOTHECIN . 24360  D09YDM  DGIdb
CORTICOTROPIN . 16132265  D0R4HQ  DGIdb
LOVASTATIN . 53232  D06WTZ  DGIdb
PIOGLITAZONE . 4829  D03OFF  DGIdb
SIMVASTATIN . 54454  D0H0ND  DGIdb
VESNARINONE . 5663  D0L0ZF  DGIdb

Protein Sequence Information

MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDP
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