Host Protein General Information

  Protein Name
Aldo-keto reductase family 1 member C4
  Gene Name
AKR1C4
  Host Species
Homo sapiens
  Uniprot Entry Name
AK1C4_HUMAN
  Protein Families
Aldo/keto reductase family
  EC Number
1.1.1.-; 1.1.1.2.9; 1.1.1.21.; 1.1.1.225; 1.1.1.357; 1.1.1.51; 1.1.1.53; 1.1.1.62
  Subcellular Location
Cytoplasm; cytosol
  External Link
NCBI Gene ID
1109
Uniprot ID
P17516
Ensembl ID
ENSG00000122966
HGNC ID
387
  Related KEGG Pathway
Primary bile acid biosynthesis hsa00120            Pathway Map 
Steroid hormone biosynthesis hsa00140            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
  3D Structure
PDB ID: 2FVL 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Hepatitis E virus 3'UTR RNA Info RNA-protein interaction detection (RaPID) assay coupled to liquid chromatography with tandem mass spectrometry (LC-MS/MS) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
DAUNORUBICIN . 30323  D01XWG  DGIdb
EXEMESTANE . 60198  D0D2VS  DGIdb
indomethacin . 3715  D0R1RS  DrugCentral

Protein Sequence Information

MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPFSDEY
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