Host Protein General Information

  Protein Name
Muscarinic acetylcholine receptor M3
  Gene Name
CHRM3
  Host Species
Homo sapiens
  Uniprot Entry Name
ACM3_HUMAN
  Protein Families
G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM3 sub-subfamily
  Subcellular Location
Cell membrane
  External Link
NCBI Gene ID
1131
Uniprot ID
P20309
Ensembl ID
ENSG00000185567
HGNC ID
1952
  Related KEGG Pathway
Calcium signaling pathway hsa04020            Pathway Map 
Neuroactive ligand-receptor interaction hsa04080            Pathway Map 
Cholinergic synapse hsa04725            Pathway Map 
Taste transduction hsa04742            Pathway Map 
Regulation of actin cytoskeleton hsa04810            Pathway Map 
Insulin secretion hsa04911            Pathway Map 
Salivary secretion hsa04970            Pathway Map 
Gastric acid secretion hsa04971            Pathway Map 
Pancreatic secretion hsa04972            Pathway Map 
Alzheimer disease hsa05010            Pathway Map 
Pathways of neurodegeneration - multiple diseases hsa05022            Pathway Map 
  3D Structure
PDB ID: 2CSA 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
4-DAMP . 3014059  D0A2KT  DGIdb
ACECLIDINE . 1979  D0R7WU  DGIdb
aceclidine . 1979  D0R7WU  DrugCentral
ACETYLCHOLINE . 187  D0Q9HF  DGIdb
acetylcholine . 187  D0Q9HF  DrugCentral
ACLIDINIUM . 11434515  D0VP1V  DGIdb
ACLIDINIUM BROMIDE . 11519741  D07KHH  DGIdb
aclidinium bromide . 11519741  D07KHH  DrugCentral
AFACIFENACIN . 10188853  D05OTZ  DGIdb
ALCURONIUM . 21158560  D0L1OY  DGIdb
alcuronium . 21158560  D0L1OY  DrugCentral
amiodarone . 2157  D0L5WM  DrugCentral
AMITRIPTYLINE . 2160  D0Y5UG  DGIdb
amitriptyline . 2160  D0Y5UG  DrugCentral
amoxapine . 2170  D09IOI  DrugCentral
ANISOTROPINE METHYLBROMIDE . 657201  D07CNL  DGIdb
ARECOLINE . 2230  D07EFM  DGIdb
aripiprazole . 60795  D0H3HM  DrugCentral
asenapine . 3036780  D00JRA  DrugCentral
ASM-024 . 117587641  D08NYZ  DGIdb
astemizole . 2247  D0Y2HR  DrugCentral
ATROPINE . 174174  D0RG3O  DGIdb
atropine . 174174  D0RG3O  DrugCentral
ATROPINE SULFATE . 174174  D0RG3O  DGIdb
benzatropine . 1201549  D0HQ6N  DrugCentral
benzethonium . . . DrugCentral
BENZQUINAMIDE . 2342  D02DKD  DGIdb
betamethasone phosphate . . . DrugCentral
BETHANECHOL . 2370  D07ZTO  DGIdb
bethanechol . 2370  D07ZTO  DrugCentral
bietamiverine . . . DrugCentral
BIPERIDEN . 2381  D0B4TN  DGIdb
biperiden . 2381  D0B4TN  DrugCentral
bromperidol . 2448  D00SHQ  DrugCentral
BRUCINE . 442021  D0H2UT  DGIdb
CARBACHOL . 5831  D0U7BW  DGIdb
carbachol . 5831  D0U7BW  DrugCentral
carbenicillin . 20824  D02TBI  DrugCentral
CEVIMELINE . 83898  D0Q4CS  DGIdb
cevimeline . 83898  D0Q4CS  DrugCentral
CEVIMELINE HYDROCHLORIDE . 83898  D0Q4CS  DGIdb
CHEMBL523685 . 3008304  D0JV2S  DGIdb
chloroquine . 2719  D09EGZ  DrugCentral
chlorpromazine . 2726  D01ZII  DrugCentral
chlorprothixene . 667467  D0B0CP  DrugCentral
cinnarizine . 1547484  D0Q3YO  DrugCentral
clemastine . 26987  D0C5XC  DrugCentral
CLIDINIUM . 2784  D0Q1BT  DGIdb
clidinium . 2784  D0Q1BT  DrugCentral
clomifene . 1548953  D0CT9Y  DrugCentral
clomipramine . 2801  D0ZS8P  DrugCentral
clotrimazole . 2812  D09GOS  DrugCentral
clozapine . 135398737  D0Z1RV  DrugCentral
cyamemazine . 62865  D0G7NW  DrugCentral
cyclizine . 6726  D08HRJ  DrugCentral
cyclobenzaprine . 2895  D01KHH  DrugCentral
cyclopentolate . 2905  D0B1EV  DrugCentral
cyproheptadine . 2913  D00TLN  DrugCentral
danazol . 28417  D09IPV  DrugCentral
DARIFENACIN . 444031  D0Y5AM  DGIdb
darifenacin . 444031  D0Y5AM  DrugCentral
desipramine . 2995  D01UTL  DrugCentral
desloratadine . 124087  D01GBY  DrugCentral
dexchlorpheniramine . . . DrugCentral
dexfenfluramine . 66265  D0F9SG  DrugCentral
dicloxacillin . 18381  D0R2KJ  DrugCentral
DICYCLOMINE . 3042  D07XJM  DGIdb
dicycloverine . 3042  D07XJM  DrugCentral
diethylstilbestrol . 448537  D0Y2NE  DrugCentral
dimenhydrinate . 10660  D0U8UV  DrugCentral
dimetindene . 21855  D08CTT  DrugCentral
diphemanil . 6126  D0OK5Q  DrugCentral
DIPHEMANIL METHYLSULFATE . 6126  D0OK5Q  DGIdb
diphenhydramine . 3100  D01FGR  DrugCentral
DIPHENIDOL . 3055  D0W9VB  DGIdb
diphenidol . 3055  D0W9VB  DrugCentral
disopyramide . 3114  D0M4YC  DrugCentral
dosulepin . 5282426  D0Q2MN  DrugCentral
DOTHIEPIN . 5282426  D0Q2MN  DGIdb
DOXEPIN . 667477  D06FES  DGIdb
doxepin . 667477  D06FES  DrugCentral
ebastine . . . DrugCentral
eburnamonine . 71203  D0S4DT  DrugCentral
econazole . 3198  D0EV8E  DrugCentral
femoxetine . 3012003  D08OJE  DrugCentral
fenfluramine . 3337  D09WNK  DrugCentral
FESOTERODINE . . . DGIdb
fesoterodine . . . DrugCentral
FESOTERODINE FUMARATE . 9849808  D00BLL  DGIdb
flunarizine . 941361  D05CEU  DrugCentral
fluoxetine . 3386  D0TR5X  DrugCentral
fluphenazine . 3372  D0P5SA  DrugCentral
fluphenazine enanthate . . . DrugCentral
FURTRETHONIUM . 10938  D0PL0Y  DGIdb
furtrethonium . 10938  D0PL0Y  DrugCentral
gentian violet . 11057  D04GZA  DrugCentral
GLYCOPYRROLATE . 11693  D0M0AM  DGIdb
glycopyrronium bromide . . . DrugCentral
haloperidol . 3559  D0D1AL  DrugCentral
HEXOCYCLIUM . 24199  D08TRD  DGIdb
hexocyclium . 24199  D08TRD  DrugCentral
HIMBACINE . 6436265  D06ACX  DGIdb
homatropine . . . DrugCentral
hydroxychloroquine . 3652  D0OJ4L  DrugCentral
hyoscyamine . 154417  D0RD5W  DrugCentral
imidafenacin . . . DrugCentral
imipramine . 3696  D06ZUK  DrugCentral
IPRATROPIUM . 657309  D0S0AS  DGIdb
ipratropium . 657309  D0S0AS  DrugCentral
IPRATROPIUM BROMIDE . 657309  D0S0AS  DGIdb
isopropamide . . . DrugCentral
ISOPROPAMIDE IODIDE . 6284  D0Z9PX  DGIdb
ivermectin . 6321424  D09YHJ  DrugCentral
ketotifen . 3827  D0YG7M  DrugCentral
LEVOMEPROMAZINE . 72287  D09LZT  DGIdb
lofepramine . 3947  D0K3MC  DrugCentral
loxapine . 3964  D0U5OE  DrugCentral
maprotiline . 4011  D03KQF  DrugCentral
mepacrine . 237  D0O2DQ  DrugCentral
mepenzolate . 4057  D0FV3V  DrugCentral
MEPENZOLATE BROMIDE . 4057  D0FV3V  DGIdb
mequitazine . 4066  D09IMS  DrugCentral
mesoridazine . 4078  D04AAN  DrugCentral
methacholine . 6114  D04MWJ  DrugCentral
METHACHOLINE CHLORIDE . 6114  D04MWJ  DGIdb
METHIXENE . 4167  D0NF0W  DGIdb
METHOCTRAMINE . 107759  D06UXW  DGIdb
METHSCOPOLAMINE . 71183  D0M6VK  DGIdb
methscopolamine . 71183  D0M6VK  DrugCentral
METHSCOPOLAMINE BROMIDE . 5459110  D04LHJ  DGIdb
methysergide . 9681  D0O6GC  DrugCentral
mianserin . 4184  D0R6RO  DrugCentral
miconazole . 4189  D00AXJ  DrugCentral
MILAMELINE . 9571002  D0UX0T  DGIdb
molindone . 23897  D09TPF  DrugCentral
montelukast . 5281040  D00QET  DrugCentral
N-methyl scopolamine . 71183  D0M6VK  .
nortriptyline . 4543  D04WFD  DrugCentral
octatropine methylbromide . 657201  D07CNL  DrugCentral
OLANZAPINE . 135398745  D0V4QS  DGIdb
olanzapine . 135398745  D0V4QS  DrugCentral
orphenadrine . 4601  D0D9FV  DrugCentral
OTENZEPAD . 107867  D0A2OW  DGIdb
oxiconazole . 5353853  D04GYO  DrugCentral
OXOTREMORINE . 4630  D0L1XR  DGIdb
OXYBUTYNIN . . . DGIdb
oxybutynin . . . DrugCentral
OXYPHENCYCLIMINE . 4642  D0H5DU  DGIdb
oxyphencyclimine . 4642  D0H5DU  DrugCentral
oxyphenonium . 5749  D0D1MA  DrugCentral
paroxetine . 43815  D06GDY  DrugCentral
pecazine . . . DrugCentral
perhexiline . 4746  D00SBN  DrugCentral
perphenazine . 4748  D02HED  DrugCentral
PILOCARPINE . 5910  D06HLY  DGIdb
pilocarpine . 5910  D06HLY  DrugCentral
pimozide . 16362  D00KHM  DrugCentral
PIRENZEPINE . 4848  D0T0LM  DGIdb
pirenzepine . 4848  D0T0LM  DrugCentral
pridinol . . . DrugCentral
prochlorperazine . 4917  D0B2UZ  DrugCentral
procyclidine . 4919  D0R1WR  DrugCentral
PROMAZINE . 4926  D00NAX  DGIdb
promazine . 4926  D00NAX  DrugCentral
PROMETHAZINE . 4927  D0T2XU  DGIdb
promethazine . 4927  D0T2XU  DrugCentral
PROPANTHELINE . 4934  D0V5ZZ  DGIdb
propantheline . 4934  D0V5ZZ  DrugCentral
PROPANTHELINE BROMIDE . 4934  D0V5ZZ  DGIdb
PROPIOMAZINE . 4940  D0R9ZB  DGIdb
propiomazine . 4940  D0R9ZB  DrugCentral
protriptyline . 4976  D00MYQ  DrugCentral
quetiapine . 5002  D0H7KF  DrugCentral
REVEFENACIN . 11753673  D0K1ST  DGIdb
revefenacin . 11753673  D0K1ST  DrugCentral
risperidone . 5073  D01AZG  DrugCentral
SABCOMELINE . 9577995  D09FYQ  DGIdb
sabcomeline . 9577995  D09FYQ  DrugCentral
SCOPOLAMINE . 3000322  D0B7YT  DGIdb
scopolamine . 3000322  D0B7YT  DrugCentral
scopolamine butylbromide . . . DrugCentral
sertindole . 60149  D0OS6O  DrugCentral
sertraline . 68617  D0K0TC  DrugCentral
sofpironium bromide . 86301316  D0VK9O  DrugCentral
SOLIFENACIN . 154059  D0L4YD  DGIdb
solifenacin . 154059  D0L4YD  DrugCentral
SOLIFENACIN SUCCINATE . 154059  D0L4YD  DGIdb
STRYCHNINE . 441071  D0H0BD  DGIdb
strychnine . 441071  D0H0BD  DrugCentral
sulconazole . 5318  D0X8XA  DrugCentral
suloctidil . . . DrugCentral
SUXAMETHONIUM . 5314  D0Q7ZQ  DGIdb
tamoxifen . 2733526  D07KSG  DrugCentral
TARAFENACIN . 25147683  D04YEW  DGIdb
terconazole . 441383  D01AQT  DrugCentral
THIETHYLPERAZINE . 5440  D0Y0ER  DGIdb
thiethylperazine . 5440  D0Y0ER  DrugCentral
thioridazine . 5452  D0U1OE  DrugCentral
thiothixene . 941651  D0E0LQ  DrugCentral
TIOTROPIUM . 5487427  D0P1WA  DGIdb
tiotropium . 5487427  D0P1WA  .
TIOTROPIUM BROMIDE . . . DGIdb
tiotropium bromide . . . DrugCentral
TOLTERODINE . 443879  D0BZ7W  DGIdb
tolterodine . 443879  D0BZ7W  DrugCentral
TRIDIHEXETHYL . 20299  D0OK5I  DGIdb
tridihexethyl . 20299  D0OK5I  DrugCentral
trifluoperazine . 5566  D0R4OM  DrugCentral
trihexyphenidyl . 5572  D09GFL  DrugCentral
TRIPITRAMINE . 132947  D07GPQ  DGIdb
TROPICAMIDE . 5593  D09PNY  DGIdb
tropicamide . 5593  D09PNY  DrugCentral
trospium . 5284632  D05TIB  DrugCentral
TROSPIUM CHLORIDE . 5284631  D0U9FD  DGIdb
UMECLIDINIUM . 11519070  D00SLY  DGIdb
umeclidinium . 11519070  D00SLY  DrugCentral
umeclidinium . 11519070  D00SLY  .
UMECLIDINIUM BROMIDE . 11519069  D09ZOQ  DGIdb
valethamate . . . DrugCentral
VINBURNINE . 71203  D0S4DT  DGIdb
vinburnine . 71203  D0S4DT  DrugCentral
VINCAMINE . 15376  D08UGJ  DGIdb
vincamine . 15376  D08UGJ  DrugCentral
XANOMELINE . . . DGIdb
xanomeline . . . DrugCentral
ZAMIFENACIN . 3086618  D04SBH  DGIdb
ziprasidone . 60854  D0R1JV  DrugCentral
zotepine . 5736  D0T6QX  DrugCentral

Protein Sequence Information

MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL
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