Host Protein General Information

  Protein Name
Aromatic-L-amino-acid decarboxylase
  Gene Name
DDC
  Host Species
Homo sapiens
  Uniprot Entry Name
DDC_HUMAN
  Protein Families
Group II decarboxylase family
  EC Number
4.1.1.28
  External Link
NCBI Gene ID
1644
Uniprot ID
P20711
Ensembl ID
ENSG00000100314
HGNC ID
2719
  Related KEGG Pathway
Tyrosine metabolism hsa00350            Pathway Map 
Phenylalanine metabolism hsa00360            Pathway Map 
Tryptophan metabolism hsa00380            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Serotonergic synapse hsa04726            Pathway Map 
Dopaminergic synapse hsa04728            Pathway Map 
Cocaine addiction hsa05030            Pathway Map 
Amphetamine addiction hsa05031            Pathway Map 
Alcoholism hsa05034            Pathway Map 
  3D Structure
PDB ID: 3RBF 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 5'UTR - 3'UTR RNA Info Genome-wide RNA interference (RNAi) screen HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .
Dengue virus 2 5'UTR - 3'UTR RNA Info Genome-wide RNA interference (RNAi) screen HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
BENSERAZIDE . 2327  D0X8ED  DGIdb
benserazide . 2327  D0X8ED  DrugCentral
benserazide . 2327  D0X8ED  .
CARBIDOPA . 34359  D0P7JZ  DGIdb
carbidopa . 34359  D0P7JZ  DrugCentral
carbidopa . 34359  D0P7JZ  .
methyldopa . 38853  D0BA6T  DrugCentral
NICOTINE . 89594  D0T8GD  DGIdb
SIROLIMUS . 5284616  D03LJR  DGIdb

Protein Sequence Information

MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
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