Host Protein General Information

  Protein Name
Inosine-5'-monophosphate dehydrogenase 1
  Gene Name
IMPDH1
  Host Species
Homo sapiens
  Uniprot Entry Name
IMDH1_HUMAN
  Protein Families
IMPDH/GMPR family
  EC Number
1.1.1.205
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
3614
Uniprot ID
P20839
Ensembl ID
ENSG00000106348
HGNC ID
6052
  Related KEGG Pathway
Metabolic pathways hsa01100            Pathway Map 
Nucleotide metabolism hsa01232            Pathway Map 
Purine metabolism hsa00230            Pathway Map 
Drug metabolism - other enzymes hsa00983            Pathway Map 
  3D Structure
PDB ID: 1JCN 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 4 (strain DENV-4/SG/06K2270DK1/2005) 3'UTR RNA Info RNA chromatography and quantitative mass spectrometry HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 24 h . .
Dengue virus 2 (strain D2/SG/05K3295DK1/2005) 3'UTR RNA Info RNA chromatography and quantitative mass spectrometry HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
AVN-944 . 9918559  D05QIS  DGIdb
MERCAPTOPURINE . 667490  D09UZO  DGIdb
MIZORIBINE . 104762  D0G5AG  DGIdb
MYCOPHENOLATE MOFETIL . 5281078  D04FBR  DGIdb
mycophenolate mofetil . 5281078  D04FBR  DrugCentral
MYCOPHENOLIC ACID . . . DGIdb
mycophenolic acid . . . DrugCentral
RIBAVIRIN . 37542  D0H3WI  DGIdb
ribavirin . 37542  D0H3WI  DrugCentral
TARIBAVIRIN HYDROCHLORIDE . 451448  D09XUB  DGIdb
THIOGUANINE . 2723601  D02ZXM  DGIdb
thioguanine . 2723601  D02ZXM  DrugCentral
TIAZOFURIN . 457954  D0S7DV  DGIdb

Protein Sequence Information

MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
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