Host Protein General Information

  Protein Name
5-hydroxytryptamine receptor 1E
  Gene Name
HTR1E
  Host Species
Homo sapiens
  Uniprot Entry Name
5HT1E_HUMAN
  Protein Families
G-protein coupled receptor 1 family
  Subcellular Location
Cell membrane
  External Link
NCBI Gene ID
3354
Uniprot ID
P28566
Ensembl ID
ENSG00000168830
HGNC ID
5291
  Related KEGG Pathway
Serotonergic synapse hsa04726            Pathway Map 
Taste transduction hsa04742            Pathway Map 
cAMP signaling pathway hsa04024            Pathway Map 
Neuroactive ligand-receptor interaction hsa04080            Pathway Map 
  3D Structure
PDB ID: 7.00E+33 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
5-MEO-DMT . 1832  D0C5XQ  DGIdb
8-OH-DPAT . 1220  D0O3GF  DGIdb
aripiprazole . 60795  D0H3HM  DrugCentral
ASENAPINE . 3036780  D00JRA  DGIdb
asenapine . 3036780  D00JRA  DrugCentral
BRL-15,572 . 3654103  D04TVG  DGIdb
CHEMBL1256797 . 11957480  D0S2BB  DGIdb
CHEMBL275628 . 164682  D05DAG  DGIdb
chlorpromazine . 2726  D01ZII  DrugCentral
CLOZAPINE . 135398737  D0Z1RV  DGIdb
clozapine . 135398737  D0Z1RV  DrugCentral
DIHYDROERGOTAMINE . 10531  D0V3ZA  DGIdb
dihydroergotamine . 10531  D0V3ZA  DrugCentral
DONITRIPTAN . 197706  D0G5ML  DGIdb
duloxetine . 60835  D01AXB  DrugCentral
ELETRIPTAN . 77993  D02DMQ  DGIdb
eletriptan . 77993  D02DMQ  DrugCentral
ergometrine . 443884  D0C1IW  DrugCentral
ERGONOVINE . 443884  D0C1IW  DGIdb
ERGOTAMINE . 8223  D01TSI  DGIdb
ergotamine . 8223  D01TSI  DrugCentral
fluphenazine . 3372  D0P5SA  DrugCentral
fluphenazine enanthate . . . DrugCentral
FLUSPIRILENE . 3396  D0U5FS  DGIdb
fluspirilene . 3396  D0U5FS  DrugCentral
haloperidol . 3559  D0D1AL  DrugCentral
loxapine . 3964  D0U5OE  DrugCentral
lysergide . 5761  D0M7LV  DrugCentral
METERGOLINE . 28693  D0UA0I  DGIdb
metergoline . 28693  D0UA0I  DrugCentral
methylergometrine . 8226  D05AHE  DrugCentral
METHYLERGONOVINE . 8226  D05AHE  DGIdb
METHYSERGIDE . 9681  D0O6GC  DGIdb
methysergide . 9681  D0O6GC  DrugCentral
METITEPINE . 4106  D0X6MT  DGIdb
NARATRIPTAN . 4440  D0T3KI  DGIdb
naratriptan . 4440  D0T3KI  DrugCentral
OLANZAPINE . 135398745  D0V4QS  DGIdb
olanzapine . 135398745  D0V4QS  DrugCentral
oxymetazoline . 4636  D09EBS  DrugCentral
paliperidone . 115237  D0B3UJ  DrugCentral
pipamperone . 4830  D00DBO  DrugCentral
QUETIAPINE . 5002  D0H7KF  DGIdb
quetiapine . 5002  D0H7KF  DrugCentral
RAUWOLSCINE . 643606  D0Z7EA  DGIdb
RISPERIDONE . 5073  D01AZG  DGIdb
risperidone . 5073  D01AZG  DrugCentral
RIZATRIPTAN . 5078  D0S9MU  DGIdb
rizatriptan . 5078  D0S9MU  DrugCentral
SEROTONIN . 5202  D0F6CD  DGIdb
SERTINDOLE . 60149  D0OS6O  DGIdb
sertindole . 60149  D0OS6O  DrugCentral
spiperone . 5265  D05EQG  DrugCentral
SUMATRIPTAN . 5358  D0Z6UC  DGIdb
sumatriptan . 5358  D0Z6UC  DrugCentral
thioridazine . 5452  D0U1OE  DrugCentral
TRYPTAMINE . 1150  D08CJK  DGIdb
XANOMELINE . . . DGIdb
xanomeline . . . DrugCentral
YOHIMBINE . 8969  D0H4JM  DGIdb
yohimbine . 8969  D0H4JM  DrugCentral
ZIPRASIDONE . 60854  D0R1JV  DGIdb
ziprasidone . 60854  D0R1JV  DrugCentral
ZOLMITRIPTAN . 60857  D0NG7O  DGIdb
zolmitriptan . 60857  D0NG7O  DrugCentral
ZOTEPINE . 5736  D0T6QX  DGIdb
zotepine . 5736  D0T6QX  DrugCentral

Protein Sequence Information

MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
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