Host Protein General Information

  Protein Name
GTP cyclohydrolase 1
  Gene Name
GCH1
  Host Species
Homo sapiens
  Uniprot Entry Name
GCH1_HUMAN
  Protein Families
GTP cyclohydrolase I family
  EC Number
3.5.4.16
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
2643
Uniprot ID
P30793
Ensembl ID
ENSG00000131979
HGNC ID
4193
  Related KEGG Pathway
Metabolic pathways hsa01100            Pathway Map 
Biosynthesis of cofactors hsa01240            Pathway Map 
Folate biosynthesis hsa00790            Pathway Map 
  3D Structure
PDB ID: 1FB1 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 5'UTR - 3'UTR RNA Info Genome-wide RNA interference (RNAi) screen HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
GUANINE . 135398634  D08NKJ  DGIdb

Protein Sequence Information

MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS
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