Host Protein General Information

  Protein Name
4-hydroxyphenylpyruvate dioxygenase
  Gene Name
HPD
  Host Species
Homo sapiens
  Uniprot Entry Name
HPPD_HUMAN
  Protein Families
4HPPD family
  EC Number
1.13.11.27
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
3242
Uniprot ID
P32754
Ensembl ID
ENSG00000139428
HGNC ID
5147
  Related KEGG Pathway
Ubiquinone and other terpenoid-quinone biosynthesis hsa00130            Pathway Map 
Tyrosine metabolism hsa00350            Pathway Map 
Phenylalanine metabolism hsa00360            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Biosynthesis of cofactors hsa01240            Pathway Map 
  3D Structure
PDB ID: 3ISQ 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Rhinovirus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
NITISINONE . 115355  D0V1UW  DGIdb
nitisinone . 115355  D0V1UW  DrugCentral

Protein Sequence Information

MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQNLRGNLTNMETNGVVPGM
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