Host Protein General Information

  Protein Name
Casein kinase I isoform alpha
  Gene Name
CSNK1A1
  Host Species
Homo sapiens
  Uniprot Entry Name
KC1A_HUMAN
  Protein Families
Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
  EC Number
2.7.11.1
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
1452
Uniprot ID
P48729
Ensembl ID
ENSG00000113712
HGNC ID
2451
  Related KEGG Pathway
Human papillomavirus infection hsa05165            Pathway Map 
Breast cancer hsa05224            Pathway Map 
Hepatocellular carcinoma hsa05225            Pathway Map 
Gastric cancer hsa05226            Pathway Map 
Alzheimer disease hsa05010            Pathway Map 
Pathways of neurodegeneration - multiple diseases hsa05022            Pathway Map 
Wnt signaling pathway hsa04310            Pathway Map 
Hedgehog signaling pathway hsa04340            Pathway Map 
  3D Structure
PDB ID: 5FQD 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Zika virus 3'UTR RNA Info RNA-protein interaction detection (RaPID) HEK293 Cells (Human embryonic kidney cell) . Kidney 42 h Saint score = 0.91 .
Zika virus 5'UTR RNA Info RNA-protein interaction detection (RaPID) HEK293 Cells (Human embryonic kidney cell) . Kidney 42 h Saint score = 0.91 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ADAVOSERTIB . 24856436  D02KKA  DGIdb
bosutinib . 5328940  D0OB0F  DrugCentral
CHEMBL225519 . 11715767  D03DZO  DGIdb
CHEMBL406845 . ?  D06CIJ  DGIdb
CYC-116 . 6420138  D0CY1B  DGIdb
IC261 . 5288600  D0UN8H  DGIdb
ruxolitinib . 25126798  D04LKS  DrugCentral
SB-202190 . 5169  D0VC0I  DGIdb
SB-203580 . 176155  D0F8DL  DGIdb
SB-220025 . 5164  D09ICC  DGIdb
SB-242235 . 9863367  D0A9KI  DGIdb
SB-431542 . 4521392  D0C7WP  DGIdb
sorafenib . 216239  D0W5HK  DrugCentral
SP-600125 . 8515  D02PVB  DGIdb
sunitinib . 5329102  D0R0MW  DrugCentral
TAK-715 . 9952773  D0O6ZO  DGIdb

Protein Sequence Information

MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
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