Host Protein General Information

  Protein Name
Aldo-keto reductase family 1 member C2
  Gene Name
AKR1C2
  Host Species
Homo sapiens
  Uniprot Entry Name
AK1C2_HUMAN
  Protein Families
Aldo/keto reductase family
  EC Number
1.-.-.-; 1.1.1.112; 1.1.1.209; 1.1.1.357; 1.1.1.53; 1.1.1.62; 1.3.1.20
  Subcellular Location
Cytoplasm; cytosol
  External Link
NCBI Gene ID
1646
Uniprot ID
P52895
Ensembl ID
ENSG00000151632
HGNC ID
385
  Related KEGG Pathway
Chemical carcinogenesis - DNA adducts hsa05204            Pathway Map 
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
Steroid hormone biosynthesis hsa00140            Pathway Map 
  3D Structure
PDB ID: 1IHI 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Influenza A virus (strain California/7/2004 (H3N2)) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) A549 Cells (Adenocarcinoma human alveolar basal epithelial cell) . Lung . P-value = 2.3004252001895e-05 .
Influenza A virus (strain California/7/2004 (H3N2)) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h P = 2.3004252001895e-05 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
dexibuprofen . 39912  D06YPU  DrugCentral
diazepam . 3016  D07JVL  DrugCentral
flufenamic acid . 3371  D0B2WJ  DrugCentral
flurbiprofen . 3394  D0A1PX  DrugCentral
ibuprofen . 3672  D0R1QE  DrugCentral
indomethacin . 3715  D0R1RS  DrugCentral
meclofenamic acid . 4037  D08IFL  DrugCentral
medroxyprogesterone . 10631  D0I2SD  DrugCentral
mefenamic acid . 4044  D05FTJ  DrugCentral
naproxen . 156391  D0DJ1B  DrugCentral
ursodiol . 31401  D0G3SH  DrugCentral

Protein Sequence Information

MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY
    Click to Show/Hide