Host Protein General Information

  Protein Name
Neutrophil defensin 1
  Gene Name
DEFA1; DEFA1B
  Host Species
Homo sapiens
  Uniprot Entry Name
DEF1_HUMAN
  Protein Families
Alpha-defensin family
  Subcellular Location
Secreted
  External Link
NCBI Gene ID
1667
Uniprot ID
P59665
Ensembl ID
ENSG00000206047; ENSG00000240247
HGNC ID
2761
  Related KEGG Pathway
NOD-like receptor signaling pathway hsa04621            Pathway Map 
Staphylococcus aureus infection hsa05150            Pathway Map 
Transcriptional misregulation in cancer hsa05202            Pathway Map 
  3D Structure
PDB ID: 2KHT 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Ebola virus (strain VeroVP30) 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver . MIST = 0.98620317 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
HYDROCORTISONE . 5754  D0KR5B  DGIdb

Protein Sequence Information

MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC
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