Host Protein General Information

  Protein Name
Actin
  Gene Name
ACTB
  Host Species
Homo sapiens
  Uniprot Entry Name
ACTB_HUMAN
  Protein Families
Actin family
  EC Number
3.6.4.-
  Subcellular Location
Cytoplasm; cytoskeleton
  External Link
NCBI Gene ID
60
Uniprot ID
P60709
Ensembl ID
ENSG00000075624
HGNC ID
132
  Related KEGG Pathway
Platelet activation hsa04611            Pathway Map 
Neutrophil extracellular trap formation hsa04613            Pathway Map 
Leukocyte transendothelial migration hsa04670            Pathway Map 
Bacterial invasion of epithelial cells hsa05100            Pathway Map 
Vibrio cholerae infection hsa05110            Pathway Map 
Pathogenic Escherichia coli infection hsa05130            Pathway Map 
Shigellosis hsa05131            Pathway Map 
Salmonella infection hsa05132            Pathway Map 
Yersinia infection hsa05135            Pathway Map 
Influenza A hsa05164            Pathway Map 
Proteoglycans in cancer hsa05205            Pathway Map 
Hepatocellular carcinoma hsa05225            Pathway Map 
Hypertrophic cardiomyopathy hsa05410            Pathway Map 
Arrhythmogenic right ventricular cardiomyopathy hsa05412            Pathway Map 
Dilated cardiomyopathy hsa05414            Pathway Map 
Viral myocarditis hsa05416            Pathway Map 
Fluid shear stress and atherosclerosis hsa05418            Pathway Map 
Apoptosis hsa04210            Pathway Map 
Regulation of actin cytoskeleton hsa04810            Pathway Map 
Motor proteins hsa04814            Pathway Map 
Focal adhesion hsa04510            Pathway Map 
Adherens junction hsa04520            Pathway Map 
Tight junction hsa04530            Pathway Map 
Gastric acid secretion hsa04971            Pathway Map 
Thyroid hormone signaling pathway hsa04919            Pathway Map 
Oxytocin signaling pathway hsa04921            Pathway Map 
Thermogenesis hsa04714            Pathway Map 
Amyotrophic lateral sclerosis hsa05014            Pathway Map 
Rap1 signaling pathway hsa04015            Pathway Map 
Hippo signaling pathway hsa04390            Pathway Map 
Phagosome hsa04145            Pathway Map 
  3D Structure
PDB ID: 3BYH 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Hepatitis C virus 5'UTR RNA Info Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/Not Specified Virus Strain) Not Specified Virus Region RNA Info RNAantisensepurificationandquantitativemassspectrometry(RAP-MS); Tandemmasstag(TMT)labelling; liquidchromatographycoupledwithtandemmassspectrometry(LC-MS/MS); Westernblot Huh7 cells (liver carcinoma celll ine) . Liver 24h log2 fold change = 4.71103E+14 .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/IPBCAMS-YL01/2020) 3'UTR RNA Info ChIRP-MS Huh7.5.1 cells . Liver 30 h MIST = 0.691965934 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
CYCLOPHOSPHAMIDE . 2907  D0CT9C  DGIdb
ETHINYL ESTRADIOL . 5991  D06NXY  DGIdb

Protein Sequence Information

MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
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