Host Protein General Information

  Protein Name
Transforming growth factor beta-2 proprotein
  Gene Name
TGFB2
  Host Species
Homo sapiens
  Uniprot Entry Name
TGFB2_HUMAN
  Protein Families
TGF-beta family
  Subcellular Location
Secreted; extracellular matrix
  External Link
NCBI Gene ID
7042
Uniprot ID
P61812
Ensembl ID
ENSG00000092969
HGNC ID
11768
  Related KEGG Pathway
Tuberculosis hsa05152            Pathway Map 
Leishmaniasis hsa05140            Pathway Map 
Chagas disease hsa05142            Pathway Map 
Malaria hsa05144            Pathway Map 
Toxoplasmosis hsa05145            Pathway Map 
Amoebiasis hsa05146            Pathway Map 
Hepatitis B hsa05161            Pathway Map 
Human T-cell leukemia virus 1 infection hsa05166            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Proteoglycans in cancer hsa05205            Pathway Map 
MicroRNAs in cancer hsa05206            Pathway Map 
Colorectal cancer hsa05210            Pathway Map 
Renal cell carcinoma hsa05211            Pathway Map 
Pancreatic cancer hsa05212            Pathway Map 
Chronic myeloid leukemia hsa05220            Pathway Map 
Hepatocellular carcinoma hsa05225            Pathway Map 
Gastric cancer hsa05226            Pathway Map 
Hypertrophic cardiomyopathy hsa05410            Pathway Map 
Dilated cardiomyopathy hsa05414            Pathway Map 
Diabetic cardiomyopathy hsa05415            Pathway Map 
Cell cycle hsa04110            Pathway Map 
Cellular senescence hsa04218            Pathway Map 
Osteoclast differentiation hsa04380            Pathway Map 
AGE-RAGE signaling pathway in diabetic complications hsa04933            Pathway Map 
Inflammatory bowel disease hsa05321            Pathway Map 
Rheumatoid arthritis hsa05323            Pathway Map 
MAPK signaling pathway hsa04010            Pathway Map 
FoxO signaling pathway hsa04068            Pathway Map 
TGF-beta signaling pathway hsa04350            Pathway Map 
Hippo signaling pathway hsa04390            Pathway Map 
Cytokine-cytokine receptor interaction hsa04060            Pathway Map 
  3D Structure
PDB ID: 1TFG 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
BELAGENPUMATUCEL-L . . D03OTH  DGIdb
FRESOLIMUMAB . . DB35WK  DGIdb

Protein Sequence Information

MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSENAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS
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