Host Protein General Information

  Protein Name
E3 ubiquitin-protein ligase Mdm2
  Gene Name
MDM2
  Host Species
Homo sapiens
  Uniprot Entry Name
MDM2_HUMAN
  Protein Families
MDM2/MDM4 family
  EC Number
2.3.2.27
  Subcellular Location
Nucleus, nucleoplasm; Cytoplasm
  External Link
NCBI Gene ID
4193
Uniprot ID
Q00987
Ensembl ID
ENSG00000135679
HGNC ID
6973
  3D Structure
PDB ID: 1RV1 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
apomorphine . 6005  D0H6QU  DrugCentral
CHEMBL35482 . 4713  D9ILC1  DGIdb
cytarabine . 6253  D07XSN  DrugCentral
HELENALIN . 23205  D0Q6YP  DGIdb
IDASANUTLIN . 53358942  D0OC4O  DGIdb
IPILIMUMAB . ?  D07BVI  DGIdb
MANGOSTIN . 5281650  D06PRC  DGIdb
NUTLIN-3 . 216345  D01QKK  DGIdb
RO-5045337 . 57406853  D08EOW  DGIdb
SERDEMETAN . 11609586  D0B3GF  DGIdb
THIRAM . 5455  D02UVS  DGIdb

Protein Sequence Information

MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
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