Host Protein General Information

  Protein Name
Pro-neuregulin-1
  Gene Name
NRG1
  Host Species
Homo sapiens
  Uniprot Entry Name
NRG1_HUMAN
  Protein Families
Neuregulin family
  Subcellular Location
Membrane; Single-pass type I membrane protein
  External Link
NCBI Gene ID
3084
Uniprot ID
Q02297
Ensembl ID
ENSG00000157168
HGNC ID
7997
  Related KEGG Pathway
EGFR tyrosine kinase inhibitor resistance hsa01521            Pathway Map 
Amyotrophic lateral sclerosis hsa05014            Pathway Map 
ErbB signaling pathway hsa04012            Pathway Map 
  3D Structure
PDB ID: 1HAE 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 5'UTR - 3'UTR RNA Info Genome-wide RNA interference (RNAi) screen HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
AFATINIB . 10184653  D05UFG  DGIdb
ALTEPLASE . ?  D07BQE  DGIdb
ASPIRIN . 2244  D0GY5Z  DGIdb
BUPIVACAINE . 2474  D0A0FL  DGIdb
CARBOPLATIN . 426756  D0X7HM  DGIdb
CETUXIMAB . ?  D0N5OV  DGIdb
CISPLATIN . 5702198  D0U5HU  DGIdb
COLCHICINE . 6167  D09DHY  DGIdb
DEXAMETHASONE . 5743  D0IT2G  DGIdb
ERLOTINIB . 176870  D07POC  DGIdb
GEMCITABINE . 60750  D03UVS  DGIdb
GENISTEIN . 5280961  D0L4FS  DGIdb
ISOPROTERENOL . 3779  D0I8FI  DGIdb
LAPATINIB . 208908  D08CDI  DGIdb
NICOTINE . 89594  D0T8GD  DGIdb
PACLITAXEL . . . DGIdb
PANITUMUMAB . ?  D0HU9H  DGIdb
PERTUZUMAB . ?  D0CI4E  DGIdb
PROGESTERONE . 5994  D07BSQ  DGIdb
TAMOXIFEN . 2733526  D07KSG  DGIdb
VINCRISTINE . 5978  D09QVV  DGIdb
WORTMANNIN . 312145  D0P1JI  DGIdb

Protein Sequence Information

MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQDPIAV
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