Host Protein General Information

  Protein Name
Angiopoietin-1 receptor
  Gene Name
TEK
  Host Species
Homo sapiens
  Uniprot Entry Name
TIE2_HUMAN
  Protein Families
Protein kinase superfamily, Tyr protein kinase family, Tie subfamily
  EC Number
2.7.10.1
  Subcellular Location
Cell membrane
  External Link
NCBI Gene ID
7010
Uniprot ID
Q02763
Ensembl ID
ENSG00000120156
HGNC ID
11724
  Related KEGG Pathway
Rheumatoid arthritis hsa05323            Pathway Map 
MAPK signaling pathway hsa04010            Pathway Map 
Ras signaling pathway hsa04014            Pathway Map 
Rap1 signaling pathway hsa04015            Pathway Map 
HIF-1 signaling pathway hsa04066            Pathway Map 
PI3K-Akt signaling pathway hsa04151            Pathway Map 
  3D Structure
PDB ID: 1FVR 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ALTIRATINIB . 54576299  D0FA6S  DGIdb
AMPICILLIN . 6249  D0YA9Z  DGIdb
ampicillin . 6249  D0YA9Z  DrugCentral
axitinib . 6450551  D01ZRI  DrugCentral
bosutinib . 5328940  D0OB0F  DrugCentral
CABOZANTINIB . 25102847  D0IQ6P  DGIdb
cabozantinib . 25102847  D0IQ6P  DrugCentral
CEP-11981 . 11751922  D0FD6D  DGIdb
CETIRIZINE . 2678  D0DK8V  DGIdb
cetirizine . 2678  D0DK8V  DrugCentral
crizotinib . 11626560  D03ZBT  DrugCentral
fedratinib . 16722836  D0G8BM  DrugCentral
infigratinib . 53235510  D03LWG  DrugCentral
LINIFANIB . 11485656  D0M9QZ  DGIdb
LOPERAMIDE . 3955  D0CS2F  DGIdb
loperamide . 3955  D0CS2F  DrugCentral
MERESTINIB . 44603533  D06EGV  DGIdb
MGCD-265 . 24901704  D08FDX  DGIdb
midostaurin . 9829523  D07NVU  DrugCentral
neratinib . . . DrugCentral
niclosamide . 4477  D0J9ZR  DrugCentral
nilotinib . 644241  D00STL  DrugCentral
nintedanib . 135423438  D09HNV  DrugCentral
pazopanib . . . DrugCentral
PEXMETINIB . 24765037  D0ML0L  DGIdb
REBASTINIB . 25066467  D0E0NM  DGIdb
REGORAFENIB . 11167602  D09GDD  DGIdb
regorafenib . 11167602  D09GDD  DrugCentral
ripretinib . 71584930  D09AAK  DrugCentral
sorafenib . 216239  D0W5HK  DrugCentral
VANDETANIB . 3081361  D0G6QF  DGIdb
vandetanib . 3081361  D0G6QF  DrugCentral

Protein Sequence Information

MDSLASLVLCGVSLLLSGTVEGAMDLILINSLPLVSDAETSLTCIASGWRPHEPITIGRDFEALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGEAIRIRTMKMRQQASFLPATLTMTVDKGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPECNHLCTACMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPDPYGCSCATGWKGLQCNEACHPGFYGPDCKLRCSCNNGEMCDRFQGCLCSPGWQGLQCEREGIQRMTPKIVDLPDHIEVNSGKFNPICKASGWPLPTNEEMTLVKPDGTVLHPKDFNHTDHFSVAIFTIHRILPPDSGVWVCSVNTVAGMVEKPFNISVKVLPKPLNAPNVIDTGHNFAVINISSEPYFGDGPIKSKKLLYKPVNHYEAWQHIQVTNEIVTLNYLEPRTEYELCVQLVRRGEGGEGHPGPVRRFTTASIGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPREQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQLKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA
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