Host Protein General Information

  Protein Name
Aldo-keto reductase family 1 member C1
  Gene Name
AKR1C1
  Host Species
Homo sapiens
  Uniprot Entry Name
AK1C1_HUMAN
  Protein Families
Aldo/keto reductase family
  EC Number
1.1.1.-; 1.1.1.112; 1.1.1.149; 1.1.1.209; 1.1.1.210; 1.1.1.357; 1.1.1.51; 1.1.1.53; 1.1.1.62; 1.3.1.20
  Subcellular Location
Cytoplasm; cytosol
  External Link
NCBI Gene ID
1645
Uniprot ID
Q04828
Ensembl ID
ENSG00000187134
HGNC ID
384
  Related KEGG Pathway
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Steroid hormone biosynthesis hsa00140            Pathway Map 
Metabolism of xenobiotics by cytochrome P450 hsa00980            Pathway Map 
  3D Structure
PDB ID: 1MRQ 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Hepatitis B virus (strain ayw) 5'UTR - 3'UTR RNA Info Co-immunoprecipitation mass spectrometry (Co-IP/MS) HepaRG Cell (Human bipotent progenitor cell line) . Liver 1 h P-value (- Benzonase) = 1.99E-04 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
benzbromarone . 2333  D0Z3DY  DrugCentral
CHEMBL449129 . 9445  D06SPO  DGIdb
CHEMBL562352 . 11009103  D0MC5H  DGIdb
diazepam . 3016  D07JVL  DrugCentral
ESTRONE . 5870  D00ZFP  DGIdb
flufenamic acid . 3371  D0B2WJ  DrugCentral
meclofenamic acid . 4037  D08IFL  DrugCentral
medroxyprogesterone . 10631  D0I2SD  DrugCentral
mefenamic acid . 4044  D05FTJ  DrugCentral
PROGESTERONE . 5994  D07BSQ  DGIdb

Protein Sequence Information

MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY
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