Host Protein General Information

  Protein Name
Amidophosphoribosyltransferase
  Gene Name
PPAT
  Host Species
Homo sapiens
  Uniprot Entry Name
PUR1_HUMAN
  Protein Families
Purine/pyrimidine phosphoribosyltransferase family
  EC Number
2.4.2.14
  External Link
NCBI Gene ID
5471
Uniprot ID
Q06203
Ensembl ID
ENSG00000128059
HGNC ID
9238
  Related KEGG Pathway
Alanine, aspartate and glutamate metabolism hsa00250            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Purine metabolism hsa00230            Pathway Map 
  3D Structure
AlphaFold ID: Q06203 
  2D PNG Download  
  mmCIF File Download   
  PDB File Download   

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h P = 0.00659612799732351 .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h P = 0.00045974643303576 .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h P = 0.000193505858069214 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
AZATHIOPRINE . 2265  D07QCE  DGIdb
AZATHIOPRINE SODIUM . 2265  D07QCE  DGIdb
MERCAPTOPURINE . 667490  D09UZO  DGIdb
MERCAPTOPURINE . 667490  D09UZO  DGIdb
mercaptopurine . 667490  D09UZO  DrugCentral

Protein Sequence Information

MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKEKKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW
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