Host Protein General Information

  Protein Name
Son of sevenless homolog 1
  Gene Name
SOS1
  Host Species
Homo sapiens
  Uniprot Entry Name
SOS1_HUMAN
  External Link
NCBI Gene ID
6654
Uniprot ID
Q07889
Ensembl ID
ENSG00000115904
HGNC ID
11187
  Related KEGG Pathway
Chemokine signaling pathway hsa04062            Pathway Map 
Natural killer cell mediated cytotoxicity hsa04650            Pathway Map 
T cell receptor signaling pathway hsa04660            Pathway Map 
B cell receptor signaling pathway hsa04662            Pathway Map 
Fc epsilon RI signaling pathway hsa04664            Pathway Map 
Hepatitis C hsa05160            Pathway Map 
Hepatitis B hsa05161            Pathway Map 
Human cytomegalovirus infection hsa05163            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
EGFR tyrosine kinase inhibitor resistance hsa01521            Pathway Map 
Endocrine resistance hsa01522            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Proteoglycans in cancer hsa05205            Pathway Map 
MicroRNAs in cancer hsa05206            Pathway Map 
Chemical carcinogenesis - receptor activation hsa05207            Pathway Map 
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
Choline metabolism in cancer hsa05231            Pathway Map 
Colorectal cancer hsa05210            Pathway Map 
Renal cell carcinoma hsa05211            Pathway Map 
Endometrial cancer hsa05213            Pathway Map 
Glioma hsa05214            Pathway Map 
Prostate cancer hsa05215            Pathway Map 
Chronic myeloid leukemia hsa05220            Pathway Map 
Acute myeloid leukemia hsa05221            Pathway Map 
Non-small cell lung cancer hsa05223            Pathway Map 
Breast cancer hsa05224            Pathway Map 
Hepatocellular carcinoma hsa05225            Pathway Map 
Gastric cancer hsa05226            Pathway Map 
Regulation of actin cytoskeleton hsa04810            Pathway Map 
Focal adhesion hsa04510            Pathway Map 
Gap junction hsa04540            Pathway Map 
Insulin signaling pathway hsa04910            Pathway Map 
GnRH signaling pathway hsa04912            Pathway Map 
Estrogen signaling pathway hsa04915            Pathway Map 
Prolactin signaling pathway hsa04917            Pathway Map 
Relaxin signaling pathway hsa04926            Pathway Map 
Growth hormone synthesis, secretion and action hsa04935            Pathway Map 
Thermogenesis hsa04714            Pathway Map 
Neurotrophin signaling pathway hsa04722            Pathway Map 
MAPK signaling pathway hsa04010            Pathway Map 
ErbB signaling pathway hsa04012            Pathway Map 
Ras signaling pathway hsa04014            Pathway Map 
FoxO signaling pathway hsa04068            Pathway Map 
Phospholipase D signaling pathway hsa04072            Pathway Map 
mTOR signaling pathway hsa04150            Pathway Map 
PI3K-Akt signaling pathway hsa04151            Pathway Map 
JAK-STAT signaling pathway hsa04630            Pathway Map 
Alcoholism hsa05034            Pathway Map 
  3D Structure
PDB ID: 1AWE 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h . .

Protein Sequence Information

MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
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