Host Protein General Information

  Protein Name
Tau-protein kinase PRKAA1
  Gene Name
PRKAA1
  Host Species
Homo sapiens
  Uniprot Entry Name
AAPK1_HUMAN
  Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily
  EC Number
2.7.11.1; 2.7.11.26; 2.7.11.27; 2.7.11.31
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
5562
Uniprot ID
Q13131
Ensembl ID
ENSG00000132356
HGNC ID
9376
  Related KEGG Pathway
Longevity regulating pathway hsa04211            Pathway Map 
Longevity regulating pathway - multiple species hsa04213            Pathway Map 
Hypertrophic cardiomyopathy hsa05410            Pathway Map 
Fluid shear stress and atherosclerosis hsa05418            Pathway Map 
Tight junction hsa04530            Pathway Map 
Insulin resistance hsa04931            Pathway Map 
Non-alcoholic fatty liver disease hsa04932            Pathway Map 
Alcoholic liver disease hsa04936            Pathway Map 
Insulin signaling pathway hsa04910            Pathway Map 
Adipocytokine signaling pathway hsa04920            Pathway Map 
Oxytocin signaling pathway hsa04921            Pathway Map 
Glucagon signaling pathway hsa04922            Pathway Map 
Circadian rhythm hsa04710            Pathway Map 
Thermogenesis hsa04714            Pathway Map 
FoxO signaling pathway hsa04068            Pathway Map 
mTOR signaling pathway hsa04150            Pathway Map 
PI3K-Akt signaling pathway hsa04151            Pathway Map 
AMPK signaling pathway hsa04152            Pathway Map 
Apelin signaling pathway hsa04371            Pathway Map 
Autophagy - animal hsa04140            Pathway Map 
  3D Structure
PDB ID: 4RED 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
bosutinib . 5328940  D0OB0F  DrugCentral
cepharanthine . . . DrugCentral
crizotinib . 11626560  D03ZBT  DrugCentral
CYC-116 . 6420138  D0CY1B  DGIdb
DOVITINIB . 135611162  D07OZR  DGIdb
EHNA . 3206  D05ZHQ  .
ENTRECTINIB . 25141092  D0O0LS  DGIdb
fedratinib . 16722836  D0G8BM  DrugCentral
HESPERADIN . 135421442  D05WSM  DGIdb
ILORASERTIB . 46207586  D08HOM  DGIdb
JNJ-7706621 . 5330790  D04NGS  DGIdb
LY-2090314 . 10029385  D0Z1DH  DGIdb
METFORMIN . 4091  D0D7LA  DGIdb
midostaurin . 9829523  D07NVU  DrugCentral
nintedanib . 135423438  D09HNV  DrugCentral
PALBOCICLIB . 5330286  D00UZR  DGIdb
PD-0166285 . 5311382  D0H8KG  DGIdb
PENTOSTATIN . 439693  D0T3AD  .
PENTOSTATIN . 439693  D0T3AD  DGIdb
PF-00562271 . 11713159  D01SJT  DGIdb
PHENFORMIN . 8249  D07XPE  DGIdb
SIROLIMUS . 5284616  D03LJR  DGIdb
SIROLIMUS . 5284616  D03LJR  .
STREPTOZOCIN . 29327  D0I8RR  DGIdb
STREPTOZOTOCIN . 29327  D0I8RR  .
sunitinib . 5329102  D0R0MW  DrugCentral
TAE-684 . 16038120  D0R2WK  DGIdb
TOZASERTIB . 5494449  D02XNW  DGIdb
vandetanib . 3081361  D0G6QF  DrugCentral

Protein Sequence Information

MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
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