Host Protein General Information

  Protein Name
Interleukin-18
  Gene Name
IL18
  Host Species
Homo sapiens
  Uniprot Entry Name
IL18_HUMAN
  Protein Families
IL-1 family
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
3606
Uniprot ID
Q14116
Ensembl ID
ENSG00000150782
HGNC ID
5986
  Related KEGG Pathway
NOD-like receptor signaling pathway hsa04621            Pathway Map 
Cytosolic DNA-sensing pathway hsa04623            Pathway Map 
Pathogenic Escherichia coli infection hsa05130            Pathway Map 
Shigellosis hsa05131            Pathway Map 
Salmonella infection hsa05132            Pathway Map 
Legionellosis hsa05134            Pathway Map 
Yersinia infection hsa05135            Pathway Map 
Tuberculosis hsa05152            Pathway Map 
African trypanosomiasis hsa05143            Pathway Map 
Malaria hsa05144            Pathway Map 
Influenza A hsa05164            Pathway Map 
Lipid and atherosclerosis hsa05417            Pathway Map 
Inflammatory bowel disease hsa05321            Pathway Map 
Rheumatoid arthritis hsa05323            Pathway Map 
Cytokine-cytokine receptor interaction hsa04060            Pathway Map 
Viral protein interaction with cytokine and cytokine receptor hsa04061            Pathway Map 
  3D Structure
PDB ID: 1J0S 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
COLCHICINE . 6167  D09DHY  DGIdb
GSK-1070806 . . D06XDS  DGIdb
RIBAVIRIN . 37542  D0H3WI  DGIdb
TACROLIMUS . 445643  D06OMK  DGIdb

Protein Sequence Information

MAAEPVEDNCINFVAMKFIDNTLYFIAEDDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
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