Host Protein General Information

  Protein Name
Proline-rich AKT1 substrate 1
  Gene Name
AKT1S1
  Host Species
Homo sapiens
  Uniprot Entry Name
AKTS1_HUMAN
  Subcellular Location
Cytoplasm; cytosol
  External Link
NCBI Gene ID
84335
Uniprot ID
Q96B36
Ensembl ID
ENSG00000204673
HGNC ID
28426
  Related KEGG Pathway
Shigellosis hsa05131            Pathway Map 
Longevity regulating pathway hsa04211            Pathway Map 
Longevity regulating pathway - multiple species hsa04213            Pathway Map 
Thermogenesis hsa04714            Pathway Map 
mTOR signaling pathway hsa04150            Pathway Map 
AMPK signaling pathway hsa04152            Pathway Map 
Autophagy - animal hsa04140            Pathway Map 
  3D Structure
PDB ID: 5WBL 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Zika virus 5'UTR RNA Info RNA-protein interaction detection (RaPID) HEK293 Cells (Human embryonic kidney cell) . Kidney 42 h Saint score = 0.94 .
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
AZD-8055 . 25262965  D0K1VK  DGIdb
GEDATOLISIB . 44516953  D0D8JB  DGIdb
OSI-027 . 135398516  D0H7XL  DGIdb
SAPANISERTIB . 45375953  D03DPZ  DGIdb

Protein Sequence Information

MASGRPEELWEAVVGAAERFRARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIALAHRAATAARPPAPPPAPQPPSPTPSPPRPTLAREDNEEDEDEPTETETSGEQLGISDNGGLFVMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPTCSVPPASALPTQQYAKSLPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPRLNTSDFQKLKRKY
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