Host Protein General Information

  Protein Name
SRSF protein kinase 1
  Gene Name
SRPK1
  Host Species
Homo sapiens
  Uniprot Entry Name
SRPK1_HUMAN
  Protein Families
Protein kinase superfamily
  EC Number
2.7.11.1
  Subcellular Location
Cytoplasm; Nucleus matrix; Microsome
  External Link
NCBI Gene ID
6732
Uniprot ID
Q96SB4
Ensembl ID
ENSG00000096063
HGNC ID
11305
  Related KEGG Pathway
Herpes simplex virus 1 infection hsa05168            Pathway Map 
  3D Structure
PDB ID: 1WAK 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Sindbis virus 5'UTR - 3'UTR RNA Info comparative RIC HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 18 h P = 2.0579569656705 .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/Not Specified Virus Strain) N region RNA Info RNA pull-down assays; liquid chromatography with tandem mass spectrometry (LC-MS/MS); Wilcoxon test; MS2 affinity purification coupled with liquid chromatography-mass spectrometry (MAMS) Calu-3 cell line . Liver . P value < 0.05 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
alectinib . 49806720  D0U3SY  DrugCentral
ALISERTIB . 24771867  D0S4JK  DGIdb
axitinib . 6450551  D01ZRI  DrugCentral
crizotinib . 11626560  D03ZBT  DrugCentral
DOVITINIB . 135611162  D07OZR  DGIdb
fedratinib . 16722836  D0G8BM  DrugCentral
GSK-269962A . 16095342  D02ZQS  DGIdb
HESPERADIN . 135421442  D05WSM  DGIdb
LINIFANIB . 11485656  D0M9QZ  DGIdb
LY-2090314 . 10029385  D0Z1DH  DGIdb
midostaurin . 9829523  D07NVU  DrugCentral
nintedanib . 135423438  D09HNV  DrugCentral
PF-00562271 . 11713159  D01SJT  DGIdb
ruboxistaurin . 153999  D0W3LI  DrugCentral
ruxolitinib . 25126798  D04LKS  DrugCentral
SNS-314 . 24995524  D0OA5G  DGIdb
SORAFENIB . 216239  D0W5HK  DGIdb
sunitinib . 5329102  D0R0MW  DrugCentral
TAE-684 . 16038120  D0R2WK  DGIdb

Protein Sequence Information

MERKVLALQARKKRTKAKKDKAQRKSETQHRGSAPHSESDLPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLKENPPNKMTQEKLEESSTIGQDQTLMERDTEGGAAEINCNGVIEVINYTQNSNNETLRHKEDLHNANDCDVQNLNQESSFLSSQNGDSSTSQETDSCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIRAEIPCEDEQEQEHNGPLDNKGKSTAGNFLVNPLEPKNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS
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