Host Protein General Information

  Protein Name
Serine/threonine-protein kinase D2
  Gene Name
PRKD2
  Host Species
Homo sapiens
  Uniprot Entry Name
KPCD2_HUMAN
  Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily
  EC Number
2.7.11.13
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
25865
Uniprot ID
Q9BZL6
Ensembl ID
ENSG00000105287
HGNC ID
17293
  Related KEGG Pathway
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
Aldosterone synthesis and secretion hsa04925            Pathway Map 
Rap1 signaling pathway hsa04015            Pathway Map 
  3D Structure
PDB ID: 2COA 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
AZD-1080 . 135564570  D0MC0O  DGIdb
BMS-345541 . 9926054  D00YTQ  DGIdb
CEDIRANIB . 9933475  D09VMI  DGIdb
CHEMBL210618 . 11624601  D00HVA  DGIdb
CHEMBL225519 . 11715767  D03DZO  DGIdb
CYC-116 . 6420138  D0CY1B  DGIdb
DORAMAPIMOD . 156422  D05CDF  DGIdb
DOVITINIB . 135611162  D07OZR  DGIdb
ERLOTINIB . 176870  D07POC  DGIdb
FASUDIL . 3547  D03KKR  DGIdb
GEFITINIB . 123631  D09XZB  DGIdb
GO-6976 . 3501  D08JPU  DGIdb
GSK-269962A . 16095342  D02ZQS  DGIdb
ILORASERTIB . 46207586  D08HOM  DGIdb
LAUROGUADINE . . . DGIdb
midostaurin . 9829523  D07NVU  DrugCentral
neratinib . . . DrugCentral
nintedanib . 135423438  D09HNV  DrugCentral
PF-00562271 . 11713159  D01SJT  DGIdb
QUERCETIN . 5280343  D0K8KX  DGIdb
R-1487 . 11406590  D04YHW  DGIdb
R-406 . 11213558  D0S6TK  DGIdb
ruboxistaurin . 153999  D0W3LI  DrugCentral
RUCAPARIB . 9931954  D01SHZ  DGIdb
SB-203580 . 176155  D0F8DL  DGIdb
SB-220025 . 5164  D09ICC  DGIdb
SNS-314 . 24995524  D0OA5G  DGIdb
SP-600125 . 8515  D02PVB  DGIdb
sunitinib . 5329102  D0R0MW  DrugCentral
TAE-684 . 16038120  D0R2WK  DGIdb
TAK-715 . 9952773  D0O6ZO  DGIdb
TOZASERTIB . 5494449  D02XNW  DGIdb
VX-702 . 10341154  D0D9AH  DGIdb

Protein Sequence Information

MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGSGVSFHIQIGLTREFVLLPAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDLVEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSSSSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALHASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGEMPGGTPGGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLPGSGLPTDRDLGGACPPQDHDMQGLAERISVL
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