Host Protein General Information

  Protein Name
STE20-like serine/threonine-protein kinase
  Gene Name
SLK
  Host Species
Homo sapiens
  Uniprot Entry Name
SLK_HUMAN
  Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
  EC Number
2.7.11.1
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
9748
Uniprot ID
Q9H2G2
Ensembl ID
ENSG00000065613
HGNC ID
11088
  Related KEGG Pathway
Oocyte meiosis hsa04114            Pathway Map 
  3D Structure
PDB ID: 2J51 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Influenza A virus (strain California/7/2004 (H3N2)) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h P = 0.000155857347427484 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
afatinib . 10184653  D05UFG  DrugCentral
ALISERTIB . 24771867  D0S4JK  DGIdb
axitinib . 6450551  D01ZRI  DrugCentral
bosutinib . 5328940  D0OB0F  DrugCentral
CEDIRANIB . 9933475  D09VMI  DGIdb
CHEMBL225519 . 11715767  D03DZO  DGIdb
CHIR-99021 . 9956119  D0YK9D  DGIdb
crizotinib . 11626560  D03ZBT  DrugCentral
CYC-116 . 6420138  D0CY1B  DGIdb
DANUSERTIB . 11442891  D02RJY  DGIdb
DASATINIB . 3062316  D0E6XR  DGIdb
dasatinib . 3062316  D0E6XR  DrugCentral
DOVITINIB . 135611162  D07OZR  DGIdb
ENTRECTINIB . 25141092  D0O0LS  DGIdb
ERLOTINIB . 176870  D07POC  DGIdb
erlotinib . 176870  D07POC  DrugCentral
fedratinib . 16722836  D0G8BM  DrugCentral
GEFITINIB . 123631  D09XZB  DGIdb
gefitinib . 123631  D09XZB  DrugCentral
GSK-269962A . 16095342  D02ZQS  DGIdb
HESPERADIN . 135421442  D05WSM  DGIdb
ILORASERTIB . 46207586  D08HOM  DGIdb
lapatinib . 208908  D08CDI  DrugCentral
LINIFANIB . 11485656  D0M9QZ  DGIdb
LY-2090314 . 10029385  D0Z1DH  DGIdb
midostaurin . 9829523  D07NVU  DrugCentral
neratinib . . . DrugCentral
nintedanib . 135423438  D09HNV  DrugCentral
pazopanib . . . DrugCentral
PF-00562271 . 11713159  D01SJT  DGIdb
quizartinib . 24889392  D07KYT  DrugCentral
R-406 . 11213558  D0S6TK  DGIdb
ruboxistaurin . 153999  D0W3LI  DrugCentral
SB-203580 . 176155  D0F8DL  DGIdb
SNS-314 . 24995524  D0OA5G  DGIdb
SORAFENIB . 216239  D0W5HK  DGIdb
sorafenib . 216239  D0W5HK  DrugCentral
SP-600125 . 8515  D02PVB  DGIdb
sunitinib . 5329102  D0R0MW  DrugCentral
TAE-684 . 16038120  D0R2WK  DGIdb
TAK-715 . 9952773  D0O6ZO  DGIdb
TOZASERTIB . 5494449  D02XNW  DGIdb
vandetanib . 3081361  D0G6QF  DrugCentral

Protein Sequence Information

MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS
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