Host Protein General Information

  Protein Name
cAMP and cGMP phosphodiesterase 11A
  Gene Name
PDE11A
  Host Species
Homo sapiens
  Uniprot Entry Name
PDE11_HUMAN
  Protein Families
Cyclic nucleotide phosphodiesterase family
  EC Number
3.1.4.35; 3.1.4.53
  Subcellular Location
Cytoplasm; cytosol
  External Link
NCBI Gene ID
50940
Uniprot ID
Q9HCR9
Ensembl ID
ENSG00000128655
HGNC ID
8773
  Related KEGG Pathway
Cushing syndrome hsa04934            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Purine metabolism hsa00230            Pathway Map 
Morphine addiction hsa05032            Pathway Map 
  3D Structure
AlphaFold ID: . 
  2D PNG Download  
  mmCIF File Download   
  PDB File Download   

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
dipyridamole . 3108  D0F9GE  DrugCentral
mezlocillin . 656511  D00NJJ  DrugCentral
oxacillin . 6196  D0MB8I  DrugCentral
sildenafil . 135398744  D0Z7ZM  DrugCentral
TADALAFIL . 110635  D05MQK  DGIdb
tadalafil . 110635  D05MQK  DrugCentral
vardenafil . 135400189  D0C9SY  DrugCentral

Protein Sequence Information

MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSSLAHSTCRGGSSVGGGTGPNGSAHSQPLPGGGDCGGVPLSPSWAGGSRGDGNLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPRYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPASVMVAKEDRN
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