Host Protein General Information

  Protein Name
Cyclin-dependent kinase inhibitor 2A
  Gene Name
CDKN2A
  Host Species
Homo sapiens
  Uniprot Entry Name
CDN2A_HUMAN
  Protein Families
CDKN2 cyclin-dependent kinase inhibitor family
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
1029
Uniprot ID
P42771
Ensembl ID
ENSG00000069345
HGNC ID
1787
  Related KEGG Pathway
Human cytomegalovirus infection hsa05163            Pathway Map 
Human T-cell leukemia virus 1 infection hsa05166            Pathway Map 
Endocrine resistance hsa01522            Pathway Map 
Platinum drug resistance hsa01524            Pathway Map 
Cell cycle hsa04110            Pathway Map 
p53 signaling pathway hsa04115            Pathway Map 
Cellular senescence hsa04218            Pathway Map 
Cushing syndrome hsa04934            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Viral carcinogenesis hsa05203            Pathway Map 
MicroRNAs in cancer hsa05206            Pathway Map 
Pancreatic cancer hsa05212            Pathway Map 
Glioma hsa05214            Pathway Map 
Melanoma hsa05218            Pathway Map 
Bladder cancer hsa05219            Pathway Map 
Chronic myeloid leukemia hsa05220            Pathway Map 
Non-small cell lung cancer hsa05223            Pathway Map 
Hepatocellular carcinoma hsa05225            Pathway Map 
  3D Structure
PDB ID: 1A5E 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Sindbis virus 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ABEMACICLIB . 46220502  D05SBO  DGIdb
ALECTINIB . 49806720  D0U3SY  DGIdb
CARBOPLATIN . 426756  D0X7HM  DGIdb
CRIZOTINIB . 11626560  D03ZBT  DGIdb
DABRAFENIB . 44462760  D05ROI  DGIdb
GEMCITABINE . 60750  D03UVS  DGIdb
GSK-461364 . 15983966  D08RMJ  DGIdb
HMN-214 . 9888590  D0R7ID  DGIdb
IMATINIB . 5291  D0AZ3C  DGIdb
LETROZOLE . 3902  D0C1WH  DGIdb
PACLITAXEL . . . DGIdb
PALBOCICLIB . 5330286  D00UZR  DGIdb
PANITUMUMAB . ?  D0HU9H  DGIdb
RIBOCICLIB . 44631912  D08MXP  DGIdb
RIGOSERTIB . 6918736  D0KF9Q  DGIdb
SAPANISERTIB . 45375953  D03DPZ  DGIdb
TRAMETINIB . 11707110  D04XVN  DGIdb
VEMURAFENIB . 42611257  D0Y9EW  DGIdb

Protein Sequence Information

MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD
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