Host Protein General Information

  Protein Name
Diacylglycerol O-acyltransferase 1
  Gene Name
DGAT1
  Host Species
Homo sapiens
  Uniprot Entry Name
DGAT1_HUMAN
  Protein Families
Membrane-bound acyltransferase family, Sterol o-acyltransferase subfamily
  EC Number
2.3.1.20; 2.3.1.76
  Subcellular Location
Endoplasmic reticulum membrane
  External Link
NCBI Gene ID
8694
Uniprot ID
O75907
Ensembl ID
ENSG00000185000
HGNC ID
2843
  Related KEGG Pathway
Fat digestion and absorption hsa04975            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Glycerolipid metabolism hsa00561            Pathway Map 
Retinol metabolism hsa00830            Pathway Map 
  3D Structure
PDB ID: 6VP0 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Ebola virus (strain VeroVP30) 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver . MIST = 0.986163599 .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
AZD-7687 . 42636350  D0EY0A  DGIdb
HESPERETIN . 72281  D07MGA  DGIdb
icosapent ethyl . . . DrugCentral
PF-04620110 . 46926360  D0M0NT  DGIdb
PRADIGASTAT . 53387035  D0F1CE  DGIdb

Protein Sequence Information

MGDRGSSRRRRTGSRPSSHGGGGPAAAEEEVRDAAAGPDVGAAGDAPAPAPNKDGDAGVGSGHWELRCHRLQDSLFSSDSGFSNYRGILNWCVVMLILSNARLFLENLIKYGILVDPIQVVSLFLKDPYSWPAPCLVIAANVFAVAAFQVEKRLAVGALTEQAGLLLHVANLATILCFPAAVVLLVESITPVGSLLALMAHTILFLKLFSYRDVNSWCRRARAKAASAGKKASSAAAPHTVSYPDNLTYRDLYYFLFAPTLCYELNFPRSPRIRKRFLLRRILEMLFFTQLQVGLIQQWMVPTIQNSMKPFKDMDYSRIIERLLKLAVPNHLIWLIFFYWLFHSCLNAVAELMQFGDREFYRDWWNSESVTYFWQNWNIPVHKWCIRHFYKPMLRRGSSKWMARTGVFLASAFFHEYLVSVPLRMFRLWAFTGMMAQIPLAWFVGRFFQGNYGNAAVWLSLIIGQPIAVLMYVHDYYVLNYEAPAAEA
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