Host Protein General Information

  Protein Name
Apolipoprotein E
  Gene Name
APOE
  Host Species
Homo sapiens
  Uniprot Entry Name
APOE_HUMAN
  Protein Families
Apolipoprotein A1/A4/E family
  Subcellular Location
Secreted
  External Link
NCBI Gene ID
348
Uniprot ID
P02649
Ensembl ID
ENSG00000197081
HGNC ID
613
  Related KEGG Pathway
Cholesterol metabolism hsa04979            Pathway Map 
Alzheimer disease hsa05010            Pathway Map 
  3D Structure
PDB ID: 1B68 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -6.890419097 FZR = 3.93292E-09
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -1.589414898 FZR = 1
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/Not Specified Virus Strain) Not Specified Virus Region RNA Info RNAantisensepurificationandquantitativemassspectrometry(RAP-MS); Tandemmasstag(TMT)labelling; liquidchromatographycoupledwithtandemmassspectrometry(LC-MS/MS); Westernblot Huh7 cells (liver carcinoma celll ine) . Liver 24h log2 fold change = 1.93622E+14 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ACENOCOUMAROL . 54676537  D05HFY  DGIdb
ATORVASTATIN . 60823  D01QIN  DGIdb
FENOFIBRATE . 3339  D07XGR  DGIdb
FLUVASTATIN . 446155  D08GHB  DGIdb
GANCICLOVIR . 135398740  D05ARP  DGIdb
IRBESARTAN . 3749  D00JAU  DGIdb
LORAZEPAM . 3958  D0E0OG  DGIdb
LUTEIN . . . DGIdb
PRAVASTATIN . 54687  D02RQU  DGIdb
PREDNISONE . 5865  D0IL7L  DGIdb
RITONAVIR . 392622  D0ZU9R  DGIdb
SIMVASTATIN . 54454  D0H0ND  DGIdb
SOYBEAN OIL . . D06SFX  DGIdb
STAUROSPORINE . 44259  D0E3TC  DGIdb
TRIAMCINOLONE . 31307  D03BLF  DGIdb
TROGLITAZONE . 5591  D06XZW  DGIdb
WARFARIN . 54678486  D0E3OF  DGIdb

Protein Sequence Information

MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH
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