Host Protein General Information

  Protein Name
Superoxide dismutase [Mn]
  Gene Name
SOD2
  Host Species
Homo sapiens
  Uniprot Entry Name
SODM_HUMAN
  Protein Families
Iron/manganese superoxide dismutase family
  EC Number
1.15.1.1
  Subcellular Location
Mitochondrion matrix
  External Link
NCBI Gene ID
6648
Uniprot ID
P04179
Ensembl ID
ENSG00000291237
HGNC ID
11180
  Related KEGG Pathway
Longevity regulating pathway hsa04211            Pathway Map 
Longevity regulating pathway - multiple species hsa04213            Pathway Map 
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
Lipid and atherosclerosis hsa05417            Pathway Map 
Huntington disease hsa05016            Pathway Map 
FoxO signaling pathway hsa04068            Pathway Map 
Peroxisome hsa04146            Pathway Map 
  3D Structure
PDB ID: 1AP5 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Sindbis virus 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
acetylcysteine . 12035  D06XGW  DrugCentral
CYCLOPHOSPHAMIDE . 2907  D0CT9C  DGIdb
METHOTREXATE . 126941  D0SV8E  DGIdb
PACLITAXEL . . . DGIdb

Protein Sequence Information

MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK
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