Host Protein General Information

  Protein Name
Aldehyde dehydrogenase
  Gene Name
ALDH2
  Host Species
Homo sapiens
  Uniprot Entry Name
ALDH2_HUMAN
  Protein Families
Aldehyde dehydrogenase family
  EC Number
1.2.1.3
  Subcellular Location
Mitochondrion matrix
  External Link
NCBI Gene ID
217
Uniprot ID
P05091
Ensembl ID
ENSG00000111275
HGNC ID
404
  Related KEGG Pathway
Valine, leucine and isoleucine degradation hsa00280            Pathway Map 
Lysine degradation hsa00310            Pathway Map 
Arginine and proline metabolism hsa00330            Pathway Map 
Histidine metabolism hsa00340            Pathway Map 
Tryptophan metabolism hsa00380            Pathway Map 
Glycolysis / Gluconeogenesis hsa00010            Pathway Map 
Ascorbate and aldarate metabolism hsa00053            Pathway Map 
Pyruvate metabolism hsa00620            Pathway Map 
Alcoholic liver disease hsa04936            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Biosynthesis of cofactors hsa01240            Pathway Map 
Fatty acid degradation hsa00071            Pathway Map 
Glycerolipid metabolism hsa00561            Pathway Map 
Pantothenate and CoA biosynthesis hsa00770            Pathway Map 
beta-Alanine metabolism hsa00410            Pathway Map 
  3D Structure
PDB ID: 1CW3 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Sindbis virus 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/IPBCAMS-YL01/2020) 3'UTR RNA Info ChIRP-MS Huh7.5.1 cells . Liver 30 h MIST = 0.685516758 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ACETALDEHYDE . 177  D0C7WN  DGIdb
ALCOHOL . 702  D00AMQ  DGIdb
DISULFIRAM . 3117  D0X5SD  DGIdb
disulfiram . 3117  D0X5SD  DrugCentral
PRUNETIN . 5281804  D0A9RM  DGIdb

Protein Sequence Information

MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS
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