Host Protein General Information

  Protein Name
Procathepsin L
  Gene Name
CTSL
  Host Species
Homo sapiens
  Uniprot Entry Name
CATL1_HUMAN
  Protein Families
Peptidase C1 family
  EC Number
3.4.22.15
  Subcellular Location
Lysosome
  External Link
NCBI Gene ID
1514
Uniprot ID
P07711
Ensembl ID
ENSG00000101160
HGNC ID
2537
  Related KEGG Pathway
Antigen processing and presentation hsa04612            Pathway Map 
Rheumatoid arthritis hsa05323            Pathway Map 
Autophagy - animal hsa04140            Pathway Map 
Lysosome hsa04142            Pathway Map 
Phagosome hsa04145            Pathway Map 
Apoptosis hsa04210            Pathway Map 
Proteoglycans in cancer hsa05205            Pathway Map 
Fluid shear stress and atherosclerosis hsa05418            Pathway Map 
  3D Structure
PDB ID: 1CJL 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 2.018958351 FZR = 1
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 1.546543426 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
boceprevir . 10324367  D0V3YT  DrugCentral
BORTEZOMIB . 387447  D0SH3I  DGIdb
sodium aurothiomalate . 22318  D0FH7C  DrugCentral
teicoplanin aglycone . . . DrugCentral
telaprevir . 3010818  D0X9CH  DrugCentral

Protein Sequence Information

MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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