Host Protein General Information

  Protein Name
Adenine phosphoribosyltransferase
  Gene Name
APRT
  Host Species
Homo sapiens
  Uniprot Entry Name
APT_HUMAN
  Protein Families
Purine/pyrimidine phosphoribosyltransferase family
  EC Number
2.4.2.7
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
353
Uniprot ID
P07741
Ensembl ID
ENSG00000026103
HGNC ID
626
  Related KEGG Pathway
Purine metabolism hsa00230            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Nucleotide metabolism hsa01232            Pathway Map 
  3D Structure
PDB ID: 1ORE 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -6.818453494 FZR = 6.46021E-09
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -2.926833626 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ALTEPLASE . ?  D07BQE  DGIdb

Protein Sequence Information

MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE
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