Host Protein General Information

  Protein Name
Uridine 5'-monophosphate synthase
  Gene Name
UMPS
  Host Species
Homo sapiens
  Uniprot Entry Name
UMPS_HUMAN
  Protein Families
Purine/pyrimidine phosphoribosyltransferase family; OMP decarboxylase family
  EC Number
2.4.2.10; 4.1.1.23
  External Link
NCBI Gene ID
7372
Uniprot ID
P11172
Ensembl ID
ENSG00000114491
HGNC ID
12563
  Related KEGG Pathway
Metabolic pathways hsa01100            Pathway Map 
Biosynthesis of cofactors hsa01240            Pathway Map 
Pyrimidine metabolism hsa00240            Pathway Map 
Drug metabolism - other enzymes hsa00983            Pathway Map 
  3D Structure
PDB ID: 2EAW 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -5.252109225 FZR = 8.34538E-05
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -8.145127076 FZR = 4.72E-13

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
CAPECITABINE . 60953  D00HCQ  DGIdb
FLUOROURACIL . 3385  D05LEO  DGIdb
LEUCOVORIN . . . DGIdb
oteracil . . . DrugCentral
TEGAFUR . 5386  D0F3SY  DGIdb

Protein Sequence Information

MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV
    Click to Show/Hide