Host Protein General Information

  Protein Name
Farnesyl pyrophosphate synthase
  Gene Name
FDPS
  Host Species
Homo sapiens
  Uniprot Entry Name
FPPS_HUMAN
  Protein Families
FPP/GGPP synthase family
  EC Number
2.5.1.1; 2.5.1.10
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
2224
Uniprot ID
P14324
Ensembl ID
ENSG00000160752
HGNC ID
3631
  Related KEGG Pathway
Influenza A hsa05164            Pathway Map 
Human T-cell leukemia virus 1 infection hsa05166            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Terpenoid backbone biosynthesis hsa00900            Pathway Map 
  3D Structure
PDB ID: 1YQ7 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -10.35725515 FZR = 3.66986E-22
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -4.373150256 FZR = 0.011352633

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ALENDRONATE SODIUM . 2088  D09KLR  DGIdb
ALENDRONIC ACID . 2088  D09KLR  DGIdb
alendronic acid . 2088  D09KLR  DrugCentral
ATORVASTATIN . 60823  D01QIN  DGIdb
IBANDRONIC ACID . 60852  D08SJZ  DGIdb
ibandronic acid . 60852  D08SJZ  DrugCentral
incadronic acid . . . DrugCentral
minodronic acid . 130956  D00NPT  DrugCentral
neridronic acid . 71237  D0V8PA  DrugCentral
PAMIDRONATE DISODIUM . 4674  D0BF8G  DGIdb
PAMIDRONIC ACID . 4674  D0BF8G  DGIdb
pamidronic acid . 4674  D0BF8G  DrugCentral
RISEDRONIC ACID . 5245  D0PA5S  DGIdb
risedronic acid . 5245  D0PA5S  DrugCentral
TIPIFARNIB . 159324  D07NPS  DGIdb
ZOLEDRONIC ACID . 68740  D0VM2L  DGIdb
zoledronic acid . 68740  D0VM2L  DrugCentral

Protein Sequence Information

MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
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