Host Protein General Information

  Protein Name
Cyclic AMP-responsive element-binding protein 1
  Gene Name
CREB1
  Host Species
Homo sapiens
  Uniprot Entry Name
CREB1_HUMAN
  Protein Families
BZIP family
  Subcellular Location
Nucleus
  External Link
NCBI Gene ID
1385
Uniprot ID
P16220
Ensembl ID
ENSG00000118260
HGNC ID
2345
  Related KEGG Pathway
Antigen processing and presentation hsa04612            Pathway Map 
Tuberculosis hsa05152            Pathway Map 
Hepatitis B hsa05161            Pathway Map 
Human cytomegalovirus infection hsa05163            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
Human T-cell leukemia virus 1 infection hsa05166            Pathway Map 
Kaposi sarcoma-associated herpesvirus infection hsa05167            Pathway Map 
Longevity regulating pathway hsa04211            Pathway Map 
Viral carcinogenesis hsa05203            Pathway Map 
Chemical carcinogenesis - receptor activation hsa05207            Pathway Map 
Prostate cancer hsa05215            Pathway Map 
Adrenergic signaling in cardiomyocytes hsa04261            Pathway Map 
Osteoclast differentiation hsa04380            Pathway Map 
Insulin resistance hsa04931            Pathway Map 
Cushing syndrome hsa04934            Pathway Map 
Insulin secretion hsa04911            Pathway Map 
Estrogen signaling pathway hsa04915            Pathway Map 
Melanogenesis hsa04916            Pathway Map 
Thyroid hormone synthesis hsa04918            Pathway Map 
Glucagon signaling pathway hsa04922            Pathway Map 
Renin secretion hsa04924            Pathway Map 
Aldosterone synthesis and secretion hsa04925            Pathway Map 
Relaxin signaling pathway hsa04926            Pathway Map 
Cortisol synthesis and secretion hsa04927            Pathway Map 
Parathyroid hormone synthesis, secretion and action hsa04928            Pathway Map 
Growth hormone synthesis, secretion and action hsa04935            Pathway Map 
Circadian rhythm hsa04710            Pathway Map 
Circadian entrainment hsa04713            Pathway Map 
Thermogenesis hsa04714            Pathway Map 
Vasopressin-regulated water reabsorption hsa04962            Pathway Map 
Cholinergic synapse hsa04725            Pathway Map 
Dopaminergic synapse hsa04728            Pathway Map 
Huntington disease hsa05016            Pathway Map 
Prion disease hsa05020            Pathway Map 
cGMP-PKG signaling pathway hsa04022            Pathway Map 
cAMP signaling pathway hsa04024            Pathway Map 
PI3K-Akt signaling pathway hsa04151            Pathway Map 
AMPK signaling pathway hsa04152            Pathway Map 
TNF signaling pathway hsa04668            Pathway Map 
Cocaine addiction hsa05030            Pathway Map 
Amphetamine addiction hsa05031            Pathway Map 
Alcoholism hsa05034            Pathway Map 
  3D Structure
PDB ID: 2LXT 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Poliovirus 5'UTR - 3'UTR RNA Info Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and western blotting with anti-PCBP polyclonal anti serum HeLa Cells (Human cervical carcinoma cell) . Cervix 7 h . .
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ALCOHOL . 702  D00AMQ  DGIdb
CITALOPRAM . 2771  D0Y5DO  DGIdb
LITHIUM . 3028194  D5MF8Y  DGIdb
NICOTINE . 89594  D0T8GD  DGIdb

Protein Sequence Information

MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD
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