Host Protein General Information

  Protein Name
Aspartate aminotransferase
  Gene Name
GOT1
  Host Species
Homo sapiens
  Uniprot Entry Name
AATC_HUMAN
  Protein Families
Class-I pyridoxal-phosphate-dependent aminotransferase family
  EC Number
2.6.1.1; 2.6.1.3
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
2805
Uniprot ID
P17174
Ensembl ID
ENSG00000175793
HGNC ID
4432
  Related KEGG Pathway
Arginine biosynthesis hsa00220            Pathway Map 
Alanine, aspartate and glutamate metabolism hsa00250            Pathway Map 
Cysteine and methionine metabolism hsa00270            Pathway Map 
Arginine and proline metabolism hsa00330            Pathway Map 
Tyrosine metabolism hsa00350            Pathway Map 
Phenylalanine metabolism hsa00360            Pathway Map 
Phenylalanine, tyrosine and tryptophan biosynthesis hsa00400            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Carbon metabolism hsa01200            Pathway Map 
2-Oxocarboxylic acid metabolism hsa01210            Pathway Map 
Biosynthesis of amino acids hsa01230            Pathway Map 
  3D Structure
PDB ID: 3II0 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -6.500745039 FZR = 5.33088E-08
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 1.055204092 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
aspartic acid . . . DrugCentral

Protein Sequence Information

MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ
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