Host Protein General Information

  Protein Name
Apo-1 antigen
  Gene Name
FAS
  Host Species
Homo sapiens
  Uniprot Entry Name
TNR6_HUMAN
  Subcellular Location
Cell membrane
  External Link
NCBI Gene ID
355
Uniprot ID
P25445
Ensembl ID
ENSG00000243646
HGNC ID
11920
  Related KEGG Pathway
Natural killer cell mediated cytotoxicity hsa04650            Pathway Map 
Pathogenic Escherichia coli infection hsa05130            Pathway Map 
Chagas disease hsa05142            Pathway Map 
African trypanosomiasis hsa05143            Pathway Map 
Hepatitis C hsa05160            Pathway Map 
Hepatitis B hsa05161            Pathway Map 
Measles hsa05162            Pathway Map 
Human cytomegalovirus infection hsa05163            Pathway Map 
Influenza A hsa05164            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
Kaposi sarcoma-associated herpesvirus infection hsa05167            Pathway Map 
Herpes simplex virus 1 infection hsa05168            Pathway Map 
Epstein-Barr virus infection hsa05169            Pathway Map 
Human immunodeficiency virus 1 infection hsa05170            Pathway Map 
Autoimmune thyroid disease hsa05320            Pathway Map 
Allograft rejection hsa05330            Pathway Map 
Graft-versus-host disease hsa05332            Pathway Map 
Platinum drug resistance hsa01524            Pathway Map 
MAPK signaling pathway hsa04010            Pathway Map 
Cytokine-cytokine receptor interaction hsa04060            Pathway Map 
p53 signaling pathway hsa04115            Pathway Map 
Apoptosis hsa04210            Pathway Map 
Necroptosis hsa04217            Pathway Map 
TNF signaling pathway hsa04668            Pathway Map 
Non-alcoholic fatty liver disease hsa04932            Pathway Map 
Alcoholic liver disease hsa04936            Pathway Map 
Type I diabetes mellitus hsa04940            Pathway Map 
Alzheimer disease hsa05010            Pathway Map 
Pathways of neurodegeneration - multiple diseases hsa05022            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Proteoglycans in cancer hsa05205            Pathway Map 
Lipid and atherosclerosis hsa05417            Pathway Map 
  3D Structure
PDB ID: 1DDF 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 5'UTR - 3'UTR RNA Info UV cross-linking (UVX) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 30 h . .
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info UV cross-linking followed by antisense-mediated affinity purification and mass spectrometry HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 30 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ASPIRIN . 2244  D0GY5Z  DGIdb
ATORVASTATIN . 60823  D01QIN  DGIdb
BCG VACCINE . . D0A8LZ  DGIdb
CHOLECALCIFEROL . 5280795  D0K5WS  DGIdb
CISPLATIN . 5702198  D0U5HU  DGIdb
CYCLOPHOSPHAMIDE . 2907  D0CT9C  DGIdb
DAUNORUBICIN . 30323  D01XWG  DGIdb
EDELFOSINE . . D0Z7AM  DGIdb
FLOXURIDINE . 5790  D0TS1Z  DGIdb
FLUOROURACIL . 3385  D05LEO  DGIdb
LITHIUM . 3028194  D5MF8Y  DGIdb
OFRANERGENE OBADENOVEC . . DU60ND  DGIdb
PROGESTERONE . 5994  D07BSQ  DGIdb
TENIPOSIDE . 452548  D01DBQ  DGIdb
TESTOSTERONE . 6013  D06XMU  DGIdb
THROMBIN . . D0KT3X  DGIdb
VESNARINONE . 5663  D0L0ZF  DGIdb

Protein Sequence Information

MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
    Click to Show/Hide