Host Protein General Information

  Protein Name
Ephrin type-A receptor 2
  Gene Name
EPHA2
  Host Species
Homo sapiens
  Uniprot Entry Name
EPHA2_HUMAN
  Protein Families
Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
  EC Number
2.7.1..1
  Subcellular Location
Cell membrane
  External Link
NCBI Gene ID
1969
Uniprot ID
P29317
Ensembl ID
ENSG00000145192
HGNC ID
3386
  3D Structure
PDB ID: 1MQB 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 5'UTR - 3'UTR RNA Info UV cross-linking (UVX) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 30 h . .
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info UV cross-linking followed by antisense-mediated affinity purification and mass spectrometry HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 30 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ALISERTIB . 24771867  D0S4JK  DGIdb
bosutinib . 5328940  D0OB0F  DrugCentral
crizotinib . 11626560  D03ZBT  DrugCentral
CYC-116 . 6420138  D0CY1B  DGIdb
DASATINIB . 3062316  D0E6XR  DGIdb
dasatinib . 3062316  D0E6XR  DrugCentral
DORSOMORPHIN . 11524144  D0Y0BK  DGIdb
fedratinib . 16722836  D0G8BM  DrugCentral
ILORASERTIB . 46207586  D08HOM  DGIdb
LINIFANIB . 11485656  D0M9QZ  DGIdb
MLN-8054 . 11712649  D0A5MC  DGIdb
nilotinib . 644241  D00STL  DrugCentral
nintedanib . 135423438  D09HNV  DrugCentral
PF-00562271 . 11713159  D01SJT  DGIdb
R-406 . 11213558  D0S6TK  DGIdb
REGORAFENIB . 11167602  D09GDD  DGIdb
SNS-314 . 24995524  D0OA5G  DGIdb
SORAFENIB . 216239  D0W5HK  DGIdb
sorafenib . 216239  D0W5HK  DrugCentral
TOZASERTIB . 5494449  D02XNW  DGIdb
VANDETANIB . 3081361  D0G6QF  DGIdb
vandetanib . 3081361  D0G6QF  DrugCentral

Protein Sequence Information

MELQAARACFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQTEPPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIPI
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