Host Protein General Information

  Protein Name
Serine hydroxymethyltransferase
  Gene Name
SHMT1
  Host Species
Homo sapiens
  Uniprot Entry Name
GLYC_HUMAN
  Protein Families
SHMT family
  EC Number
2.1.2.1
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
6470
Uniprot ID
P34896
Ensembl ID
ENSG00000188112
HGNC ID
10850
  3D Structure
PDB ID: 1BJ4 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 0.075467834 FZR = 1
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -2.888169445 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
BEVACIZUMAB . . D04KBL  DGIdb
FLUOROURACIL . 3385  D05LEO  DGIdb
IRINOTECAN . 60838  D07HOB  DGIdb
LEUCOVORIN . . . DGIdb
METHOTREXATE . 126941  D0SV8E  DGIdb
mimosine . 3862  D04ZWL  DrugCentral
pemetrexed . 135410875  D0Y4GO  DrugCentral
pyridoxine . . . DrugCentral

Protein Sequence Information

MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
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