Host Protein General Information

  Protein Name
Sepiapterin reductase
  Gene Name
SPR
  Host Species
Homo sapiens
  Uniprot Entry Name
SPRE_HUMAN
  Protein Families
Sepiapterin reductase family
  EC Number
1.1.1.153
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
6697
Uniprot ID
P35270
Ensembl ID
ENSG00000116096
HGNC ID
11257
  Related KEGG Pathway
Metabolic pathways hsa01100            Pathway Map 
Biosynthesis of cofactors hsa01240            Pathway Map 
Folate biosynthesis hsa00790            Pathway Map 
  3D Structure
PDB ID: 1Z6Z 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -4.604560786 FZR = 0.00204602
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -0.150034079 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
APREPITANT . 135413536  D0GU4K  DGIdb
BURAPITANT . 9917944  D0F1WX  DGIdb
CASOPITANT . 9917021  D00ZGA  DGIdb
DNK333 . 9939040  D0C9FF  DGIdb
EZLOPITANT . 188927  D01TBN  DGIdb
FIGOPITANT . 9914857  D07XDQ  DGIdb
NETUPITANT . 6451149  D0G3YC  DGIdb
ORVEPITANT . 9852175  D0P1YE  DGIdb
SERLOPITANT . 23653789  D0CB2B  DGIdb

Protein Sequence Information

MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK
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