Host Protein General Information

  Protein Name
17-beta-hydroxysteroid dehydrogenase type 2
  Gene Name
HSD17B2
  Host Species
Homo sapiens
  Uniprot Entry Name
DHB2_HUMAN
  Protein Families
Short-chain dehydrogenases/reductases (SDR) family
  EC Number
1.1.1.239; 1.1.1.62
  Subcellular Location
Endoplasmic reticulum membrane
  External Link
NCBI Gene ID
3294
Uniprot ID
P37059
Ensembl ID
ENSG00000086696
HGNC ID
5211
  Related KEGG Pathway
Ovarian steroidogenesis hsa04913            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Steroid hormone biosynthesis hsa00140            Pathway Map 
  3D Structure
AlphaFold ID: P37059 
  2D PNG Download  
  mmCIF File Download   
  PDB File Download   

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 4.632212668 FZR = 0.001798038
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 1.990047315 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
acetoxolone . . . DrugCentral
masoprocol . 71398  D0U3YB  DrugCentral
quercetin . 5280343  D0K8KX  DrugCentral

Protein Sequence Information

MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
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