Host Protein General Information

  Protein Name
Squalene synthase
  Gene Name
FDFT1
  Host Species
Homo sapiens
  Uniprot Entry Name
FDFT_HUMAN
  Protein Families
Phytoene/squalene synthase family
  EC Number
2.5.1.21
  Subcellular Location
Endoplasmic reticulum membrane
  External Link
NCBI Gene ID
2222
Uniprot ID
P37268
Ensembl ID
ENSG00000079459
HGNC ID
3629
  Related KEGG Pathway
Metabolic pathways hsa01100            Pathway Map 
Steroid biosynthesis hsa00100            Pathway Map 
  3D Structure
PDB ID: 1EZF 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 10.73182869 FZR = 7.01336E-24
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 1.393793548 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
amiodarone . 2157  D0L5WM  DrugCentral
LAPAQUISTAT ACETATE . 9874248  D02FXU  DGIdb
LOVASTATIN . 53232  D06WTZ  DGIdb

Protein Sequence Information

MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
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